[PDF] Top 20 Structural network efficiency is associated with cognitive impairment in small-vessel disease
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Structural network efficiency is associated with cognitive impairment in small-vessel disease
... This network is widely distributed (figure 1), involving 29 edges between 27 unique nodes (tables e-2, e-3, and ...impaired network but only 68 of 443 ... See full document
8
Plasma lipoprotein associated phospholipase A2 and superoxide dismutase are independent predicators of cognitive impairment in cerebral small vessel disease patients: diagnosis and assessment
... test. Cognitive impairment group (M CI and SCI) displayed significantly lower levels of Lp - PLA2 and SOD than the normal cognition (NC) group (see also table ...heart disease; Cr, creatinine; CSVD, ... See full document
13
Biochemical markers in vascular cognitive impairment associated with subcortical small vessel disease - A consensus report
... s disease; ADMA: Asymmetric dimethylarginine; A β 40: Beta- amyloid peptide with 40 amino acids; A β 42: Beta-amyloid peptide with 42 amino acids; BBB: Blood – brain barrier; BCB: Blood-cerebrospinal fluid ... See full document
12
Original Article Periventricular rather than deep white matter hyperintensities are associated with white matter lesion relevant vascular cognitive impairment
... small vessel diseases (SVD), including VCI-ND and vascular dementia. WMHs are recogniz- ed as vascular origin, due to hypoperfusion or chronic ischemia, and considered as markers of SVD together with lacuna ... See full document
13
Baykara, Ebru (2018): Imaging markers of cerebral small vessel disease. Dissertation, LMU München: Graduate School of Systemic Neurosciences (GSN)
... problems associated with conventional disease ...advanced disease stages (De Groot et ...conventional disease markers have only a moderate association with disease related ... See full document
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Longitudinal decline in structural networks predicts dementia in cerebral small vessel disease
... Cerebral small vessel disease (SVD) is the most common pa- thology underlying vascular ...dividually associated with cognition, but how these associations result in dementia is incompletely ... See full document
15
Ultrasound and dynamic functional imaging in vascular cognitive impairment and Alzheimer’s disease
... for impairment of CA in AD came from animal studies ...matter structural integrity (WMH and diffusion tensor imaging metrics) ...was associated with both in- creased amyloid deposition and increased ... See full document
16
Cerebrovascular disease influences functional and structural network connectivity in patients with amnestic mild cognitive impairment and Alzheimer’s disease
... The network-based degeneration hypothesis suggests that the disease-related spread of degeneration follows a pattern based on existing brain networks [5 – ...mild cognitive impair- ment (MCI) are ... See full document
15
Pathophysiology of vascular dementia
... strongly associated with AD in terms of cognitive decline and disease onset: ApoE, especially the ε 4 allele, has been observed promoting an inflammatory ...the vessel walls and in brain ... See full document
9
Apathy is associated with large-scale white matter network disruption in small vessel disease
... SMA network connectivity. The anatomy of this network is consistent with behavioral apathy, 7 suggesting that more fundamental deficits in behavioral acti- vation may be present in apathetic patients with ... See full document
12
The Brief Memory and Executive Test (BMET) for detecting vascular cognitive impairment in small vessel disease: a validation study
... Two-hundred participants with lacunar stroke were re- cruited from 19 sites across the English Stroke Research Network (see below for a list of sites). In order to match SVD patients with controls, we included all ... See full document
8
Cardiovascular risk factors and future risk of Alzheimer’s disease
... that structural imaging mar- kers of cerebral small vessel disease, such as lacunae and white matter lesions, are related to cognitive impairment or AD ...cerebral small ... See full document
9
Biomarkers for the diagnosis of Alzheimer’s disease, dementia Lewy body, frontotemporal dementia and vascular dementia
... strongly associated with all of the tested cognitive diseases, whereas the reptin:adiponectin ratio was found to be strongly associated with IS and hsCRP levels heavily associated with VaD and ... See full document
9
Functional and Structural MR Imaging in Neuropsychiatric Disorders, Part 2: Application in Schizophrenia and Autism
... of disease for im- proved ...of disease to predict the risk of asymptomatic or oli- gosymptomatic subjects developing a specific neuropsychiat- ric ...Alzheimer disease or genetically determined ... See full document
5
Cognitive impairment associated with locomotive syndrome in community-dwelling elderly women in Japan
... having cognitive impairment than the group without LS in multiple regression model 1, which is adjusted for ...that cognitive decline and dementia are associated with motor dysfunction or low ... See full document
7
Study of Correlation between Small Vessel Diseases of Brain With Cognitive Impairment in Indian Pre Dialysis Chronic Kidney Disease Patients
... A cross-sectional study was conducted on 50 patients having Chronic Kidney Disease, defined by K/DOQI guidelines (Kidney Disease Outcome Quality Initiative) with estimated GFR (eGFR) <60ml/min/1.73m2 for ... See full document
5
Cerebral small vessel disease and Alzheimer’s disease
... leads to dementia and contributes to neurodegenerative progress, including Alzheimer’s onset. Up to now, a number of studies have confirmed that CSVD can co-occur with AD, and signs of AD pathology have been found in ... See full document
10
Genetics of vascular dementia – review from the ICVD working group
... In contrast to the candidate gene studies, GWAS have recently been carried out successfully to identify novel genes underlying CSVD. For white matter hyperintensi- ties, for instance, five loci have been identified by ... See full document
7
Volume: 1.5 Review Article The Impact of Periodontal Disease upon Osteoporosis, Cognitive Impairment, Respiratory Diseases, Kidney Disease and Cancer Alison Glascoe 1*, Ronald Brown2 , Janice Mercer 3and Leslie Lawrence4
... skeletal disease characterized by low bone mass and density with deterioration of bone structure that increases the risk for fracture ...or disease such as hyperthyroidism or to medications such as steroids ... See full document
8
Up-regulation of DMN connectivity in mild cognitive impairment via network-based cognitive training
... A significant effect of the interaction was found in left superior and inferior parietal regions within the pattern of DMN connectivity (Table 3 and Fig. 3). This interaction was further explored with post hoc ... See full document
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