[PDF] Top 20 Structure of noncoding RNA is a determinant of function of RNA binding proteins in transcriptional regulation
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Structure of noncoding RNA is a determinant of function of RNA binding proteins in transcriptional regulation
... of RNA into divergent structures is constrained by specific RNA sequences under physiological condi- ...sequence-and structure- specific manners, mimicking an open promoter struc- tures and ... See full document
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Long noncoding RNAs coordinate functions between mitochondria and the nucleus
... encoded noncoding RNAs (ncRNAs), as well as proteins, is ...the regulation of almost every stage of gene expression, as well as being implicated in a variety of disease states, such as ...and ... See full document
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The multidimensional mechanisms of long noncoding RNA function
... lncRNA function are strictly dependent on the inherent properties of the RNA molecules, including their ability to fold into different structures and to conduct molecular interac- tions with other nucleic ... See full document
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Next Generation Sequencing Reveals HIV 1 Mediated Suppression of T Cell Activation and RNA Processing and Regulation of Noncoding RNA Expression in a CD4+ T Cell Line
... the RNA processing machinery was almost entirely downregulated and included many members of the heterogeneous nuclear ribonucleoprotein (hnRNP) and small nuclear ribonucleoprotein (snRNP) ...the proteins ... See full document
9
Host cell proteins binding to domain IV of the 5' noncoding region of poliovirus RNA.
... major determinant of the attenuation phenotype of the Sabin vaccine ...poliovirus RNA, indicating a role for this protein in viral translation (18); although addition of purified PTB to these immunodepleted ... See full document
9
RNA Binding of Ebola Virus VP30 Is Essential for Activating Viral Transcription
... ) RNA genome, which is complexed by the nucleoprotein (NP), VP35, polymerase L, VP24, and ...The transcriptional support activity of VP30 is strongly influenced by its phosphorylation ...how RNA ... See full document
16
Involvement of a Toxoplasma DEAD-box RNA Helicase in Post-transcriptional Gene Regulation
... to function in the repair and maintenance of nicked DNA ...NTP binding, and (iii) the carboxy domain which facilitates interfilament association ...nucleotide binding regions, one for single and ... See full document
121
Modular assembly of designer PUF proteins for specific post-transcriptional regulation of endogenous RNA
... tight binding of Pumilio domains to RNA in vitro, as well as factors determining high in vivo activities are still largely unknown, and a systematic in- vestigation is ...vitro RNA binding ... See full document
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Evf2 lncRNA/BRG1/DLX1 interactions reveal RNA dependent inhibition of chromatin remodeling
... lncRNA-mediated transcriptional repression occurs through direct lncRNA-BRG1 binding and inhibition of BRG1 ATPase and chromatin remodeling activities ...vitro binding assays show that BRG1- ... See full document
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Reprogramming of Small Noncoding RNA Populations in Peripheral Blood Reveals Host Biomarkers for Latent and Active Mycobacterium tuberculosis Infection
... snoRNA regulation has thus far hardly been explored in bacterial infections; together with the current study, SNORD104 dysregulation has been described previously in an investigation of another important ... See full document
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Affinity Profiles Categorize RNA-Binding Proteins into Distinctive Groups
... specific RNA binding site for TLS in a long noncoding RNA, pncRNA-D, which is transcribed from the promoter for cyclin D1 gene ...TLS-target RNA sequence at 32 to 44 of pncRNA-D is ... See full document
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Autoantigens interact with cis-acting elements of rubella virus RNA.
... endogenous proteins, called autoantigens, contained in ribonucleoprotein complexes ...factors binding RV RNA and whether such RNPs were recognized by antibodies in infected ...cellular ... See full document
9
Structure Function Studies of the Bacillus subtilis Ric Proteins Identify the Fe S Cluster Ligating Residues and Their Roles in Development and RNA Processing
... mutant proteins are soluble and complex formation is ...Ric proteins at multiple steps (7), it is possible that individual mutations would differ in their ultimate phenotypic effects, particularly if both ... See full document
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Long non coding RNA repertoire and targeting by nuclear exosome, cytoplasmic exonuclease and RNAi in fission yeast
... extracted RNA was assessed on a Bioanalyser instrument ...Strand-specific RNA-seq libraries were prepared using an early version of the Illumina TruSeq Small RNA Sample Prep ...2014). RNA-seq ... See full document
20
Trypanosoma brucei RRM1 Is a Nuclear RNA Binding Protein and Modulator of Chromatin Structure
... encoded RNA-binding ...PUF proteins were enriched ⬎ ...spot proteins (2- to 31-fold increases [42]) and tran- scripts with long coding regions in excess of 9 kb, such as antigenic protein ... See full document
11
Synthetic Regulation of Eukaryotic Gene Expression by Noncoding RNA
... gene regulation is often achieved using synthetic transcription factors ...interest. RNA-‐based gene control, on the other extreme, has proved versatile and modular, although generally regulatory dynamic ... See full document
139
Kcnq1ot1 noncoding RNA mediates transcriptional gene silencing by interacting with Dnmt1
... Genomic imprinting is an epigenetic phenomenon in mammals whereby the expression of a subset of autosomal genes is restricted to one of the parental chromosomes such that they are expressed either from the maternal or ... See full document
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Why is epigenetics important in understanding the pathogenesis of inflammatory musculoskeletal diseases?
... In its widest sense, the term epigenetics describes a range of mechanisms in genome function that do not solely result from the DNA sequence itself. These mechanisms comprise DNA and chromatin modifi cations and ... See full document
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<p>Emerging Roles of Long Noncoding RNA Regulator of Reprogramming in Cancer Treatment</p>
... long noncoding RNAs (lncRNAs) in cancer have attracted immense research ...well-studied RNA, regulates the progression of various cancers, such as lung cancer (LC), hepatocellular carcinoma (HCC), breast ... See full document
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Insights into long noncoding RNAs of naked mole rat ( Heterocephalus glaber ) and their potential association with cancer resistance
... The function of lncRNA 1169 in the NMR is not clear, but BLASTN searching of lncRNA 1169 as well as the other four NMR-HCRLs against the NON- CODE database found BLAST hits on the queries, not only in human but ... See full document
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