[PDF] Top 20 SYNTHESIS AND BIOLOGICAL EVALUATION OF SOME NEW PYRAZOLE DERIVATIVES
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SYNTHESIS AND BIOLOGICAL EVALUATION OF SOME NEW PYRAZOLE DERIVATIVES
... Synthesis of 4-[(2'-Phenyl-2'-imidazolin-5'- onyl)methylidene]-3-Furayl-l- phenylpyrazole(9) A Mixture of 0.2gm (0.00085 mole) of compound (2), and 0.27 gm. (0.0017 mole) of benzamidine hydrochloride dehydrate and ... See full document
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Synthesis, Characterization and Biological evaluation of substituted Pyrazole derivatives
... of synthesis, characterization and biological evaluation of substituted pyrazole ...derivatives. Pyrazole derivatives have been shown to have wide variety of ... See full document
9
SYNTHESIS AND BIOLOGICAL EVALUATION OF SOME NEW BENZOTHIAZOLE DERIVATIVES
... benzothiazole derivatives having hydrazinyl substituents and different substituents at position 4 and position 6 of electronegative atoms were synthesized with a view of enhancing the biological ...Further ... See full document
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Insilico design, synthesis, characterization and biological evaluation of some novel 1 hydroxynapthelene 2 yl derivatives
... Molecular properties of the compounds were studied by using molecule pharmacokinetic properties chalcone derivatives inflammatory activity. In an effort to continually develop potent anti-inflammatory agents, ... See full document
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Synthesis Characterization and Biological Evaluation of Some Novel Schiff’s Base and Amine Derivatives of Pyrazole
... carboxamide derivatives of pyrazole are important biologically active heterocyclic compounds ...of biological activities [2]. Pyrazole derivatives have a long history of application in ... See full document
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SYNTHESIS, CHARACTERIZATION AND BIOLOGICAL EVALUATION OF SOME NEW CHALCONES
... Synthesized compound were evaluated for antibacterial activities. Among these compounds, chloro and methoxy derives showed better activity against gram +ve bacteria whereas Dimethlyamino and chloro derivatives ... See full document
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Synthesis and antimicrobial activities of some new pyrazole derivatives
... pyrazoline derivatives have been synthesised by the condensation of pyrazoline derivatives (obtained by the reaction of various chalcones with hydrazine hydrate) with chloroacetyl chloride and glacial ... See full document
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Synthesis and biological evaluation of some new indazole-3-carboxamide derivatives
... General procedure for the preparation of 1H-indazole-3-carboxamide derivatives (4a-n): To a solution of 3 (0.1 g, 0.61 mmol, 1 equiv) in DMF, HOBT (0.1 g, 0.74 mmol, 1.2 equiv), EDC.HCl (0.141 g, 0.74 mmol, 1.2 ... See full document
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DESIGN, SYNTHESIS, MOLECULAR DOCKING, AND BIOLOGICAL EVALUATION OF PYRAZOLE 1 CARBOTHIAMIDE INCORPORATED ISOXAZOLE DERIVATIVES
... Synthesis of 5-(substituted phenyl) -3-(5-methyl-3-(4-nitrophenyl) isoxazol-4-yl) -4,5-dihydro-1H-pyrazole-1-carbothioamide and 5-(substituted phenyl) -N-methyl-3-(5-methyl-3-(4-nitrophenyl) isoxazol-4-yl) ... See full document
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Synthesis and biological evaluation of novel pyrazole derivatives as urease inhibitors
... Studies on enzyme inhibition remain an important area of pharmaceutical research since these studies have led to the discoveries of drugs useful in a variety of physiological conditions. The enzyme inhibitors can ... See full document
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Synthesis and biological evaluation of some new cyano pyridine derivatives
... the synthesis and the study of the nonglycosidic cardiotonic agent milrinone [8], as well as with a number of 3- cyanopyridine derivatives which proved to be active against the herpes virus and the human ... See full document
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Synthesis and biological evaluation of some new oxadiazole and pyrazole derivatives incorporating benzofuran moiety
... In the present work we are reporting the synthesis of compound 7-methoxy-benzofuran-2-carboxylic acid ethyl ester (1) and the various oxadiazoles 4, 5 and 7, and various pyrazoles 8, 9 and 10. The key intermediate ... See full document
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SYNTHESIS, CHARACTERIZATION, AND BIOLOGICAL EVALUATION OF PYRAZOLE DERIVATIVES
... Clinically biological activity is the result of a chemical compound’s interaction with a human ...The biological activity is dependent upon the compound’s structure and its physical-chemical ... See full document
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SYNTHESIS AND PHARMACOLOGICAL EVALUATION OF SOME NEW PYRAZOLE DERIVATIVES
... test pyrazole derivatives given by oral route at 50mg/kg did not significantly alter the reestablishment time; all animals performed normal reestablishment immediately ... See full document
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Synthesis, characterization and biological evaluation of some novel carboxamide derivatives of pyrazole
... Preparation of N-(3-fluoro-4-morpholinophenyl)-3-methyl-5-(methylthio)-1H-pyrazole-4-carboxamide (6) To a stirred solution of 2-(bis (methylthio) methylene)-N-(3-fluoro-4-morpholino phenyl) -3-oxobutanamide 5 ... See full document
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Synthesis, characterization, biological evaluation and docking studies of organo phosphorous pyrazole 5 one derivatives of 1,3,4 oxadiazole derivatives of sortase A staphylococcus inhibitors
... of new pharmaceutical materials with novel properties ...their derivatives were found to be the high light of study in lead compound discovery and biological screening and study of their various ... See full document
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Synthesis and biological evaluation of anti tubercular activity of some synthesised pyrazole derivatives
... General procedure for 5-(substituted phenyl-3-phenyl-4,5-dihydro-1H-pyrazole(4a-c). To a solution of chalcone (3a-c) in ethanol, hydrazine hydrate (99%) was added dropwise. The reaction mixture was heated under ... See full document
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Journal of Applied Pharmaceutical Science
... of some synthesis and biological evaluation of some pyrazolone derivatives with imidazole, benzimidazole and benztriazole moiety were synthesized and tested for their ... See full document
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Biological evaluation of some new 1,3-benzothiazole-2-yl derivatives containing pyrazole moiety
... Synthesis of 6-nitro-2-benzothiazolamine (2) General Procedure: A mixture of p-nitro aniline (0.01 mol) and potassium thiocyanate (0.01 mol) in 150 ml glacial acetic acid (10 %) was cooled and stirred mechanically ... See full document
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SYNTHESIS, CHARACTERIZATION, ANTIOXIDANT AND ANTI-INFLAMMATORY ACTIVITY EVALUATION OF SOME SUBSTITUTED PYRAZOLE DERIVATIVES
... ABSTRACT: A series of substituted acetophenones are condensed with hydrazides to the corresponding hydrazones which are subsequently cyclized by using volumizer-Haack reaction to give new pyrazole ... See full document
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