[PDF] Top 20 A systematic review and diagnostic test accuracy meta analysis of the validity of anion gap as a screening tool for hyperlactatemia

... and hyperlactatemia; a summary effect measure was not ...a hyperlactatemia positivity threshold of ...variance meta-anal- ysis. Subgroup analysis was undertaken to assess whether heterogeneity ... See full document

... Conclusion The high degree of unexplained statistical heterogeneity, considerable diversity between patient cohorts and poor quality of primary studies, in particular the high risk of attrition bias and confounding, ... See full document

... DTA systematic re- views, the following sources were reviewed: reporting guideline organizations’ websites (Enhancing the QUAlity and Transparency of Health Research (EQUATOR) [21]), guidance for reporting ... See full document

... This review builds on previous work by Wei et al 37 in ...statistical analysis methods when examining the accuracy performance of CAM and CAM-ICU, which had not previously been ...2 Diagnostic ... See full document

... of Diagnostic Accuracy Studies (QUADAS-2) tool 9 . The tool provided signalling questions for four key areas: patient selection, index test, reference standard and flow/timing which ... See full document

... replacement test for FIT. However, as with all cancer screening programmes, there is incomplete uptake of screening by FIT, partic- ularly so for some countries where less than half of the eligible ... See full document

... QUADAS-2 tool. Results: We meta-analysed seven studies assessing the accuracy of skin-prick testing using the bivariate random- effects model, including a total of 430 ...the accuracy of ... See full document

... A systematic review of screening test accuracy will be ...related review articles. Studies screening for FGR in a low-risk or general population using third-trimester ... See full document

... Initial screening of titles and/or abstracts and subse- quent in-depth review of full texts were done independ- ently by 2 reviewers each (AKE, GO and ...abstract screening, studies with ... See full document

... QUADAS tool by the Cochrane ...index test was used and the sample of patients was representa- tive. Index test results were blinded in all ...(index test) or not ...index test ... See full document

... invasive dye technology, with risks of side effects after injecting intravenous contrast agents [36]. In spite of accurate identification of CNV patients, the invasive in- jury could not be avoided for suspected patients ... See full document

... assess validity to their own specific clinical settings, review the inclusion criteria of the included primary ...the validity of PETS use randomized research designs rather than the accuracy ... See full document

... of diagnostic test accuracy reviews each ...of Systematic Reviews on the 7th September 2018 identi- fied 99 reviews of type ‘diagnostic’ published between October 2009 and August ... See full document

... レビューが科学的に質の高いものであるためには，文 献検索においても再現性があるものでなければならな い。検索プロセスの詳細な記述は結果の再現性を支える だけにとどまらず，レビューに有用な情報源を示唆し， 検索の厳密性・妥当性を担保するものとなる（Irwig, Tosteson, Gatsonis, Lau, Golditz, Chalmers, & Mosteller, 1994; Whiting, Rutjes, ... See full document

... our analysis of data currently available in the literature may arise from heterogeneity in the time periods at which the tests were performed, or the number of occasions on which the test was repeated prior ... See full document

... This meta-analysis has several ...this meta-analysis formally excluded patients treated with antibiotics before in- clusion ...in test performance of the various procalcitonin ...plot ... See full document

... of diagnostic test accuracy summarize the accuracy, ...of diagnostic tests in a systematic and transparent ...a review is to investigate whether a test is ... See full document

... Another limitation in comparing diagnostic-accuracy studies for molecular tools is a lack of standardization. This is clearly evidenced by the high number of different protocols presented in Table 1. ... See full document

... Background Diagnostic tests are used by clinicians to identify the presence or absence of a condition in a patient for the purpose of developing an appropriate treatment ...New diagnostic tests are ... See full document

... of meta-regression. 19 The meta-regression incorporated two planned subgroup analyses to compare whether the primary outcomes of sensitivity and specificity varied by methodological quality or diagnosis ... See full document