[PDF] Top 20 TAM receptor signaling in development
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TAM receptor signaling in development
... TAM receptor function in the developing nervous system Among TAM receptors, TYRO3 is most prominently expressed in the nervous system, both during development and throughout ...of TAM ... See full document
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Paracrine signaling in mammary gland development: what can we learn about intratumoral heterogeneity?
... gland development occurs post-natally and is regulated by both systemic hormones and local growth ...paracrine signaling pathways in mammary gland development was first sug- gested by studies in ... See full document
6
Cannabinoid receptor signaling regulates liver development and metabolism
... EC signaling pathway has predominantly been explored for its effects in the central nervous system (CNS), such as regulating appetite, mood and pain (Castillo et ...EC signaling orchestrates crucial ... See full document
14
BMP signaling regulates sympathetic nervous system development through Smad4 dependent and independent pathways
... BMP receptor Alk3 is expressed in premigratory NC cells (Panchision et ...BMP signaling during SNS development occurs through the Alk3 ...BMP signaling is essential for NC cells during mouse ... See full document
10
Macrophage IFN-I signaling promotes autoreactive T cell infiltration into islets in type 1 diabetes model
... IFNAR signaling in macrophages plays a decisive role in T1D ...IFNAR signaling in macrophages also plays a role in regulating viral con- trol during ...sphingosine-1-phosphate receptor 1 to ... See full document
14
TGF α ligands can substitute for the neuregulin Vein in Drosophila development
... factor receptor (Egfr), are activated by EGF ligands to govern cell proliferation, survival, migration and ...in development are regulated by deployment of multiple ...in development could be largely ... See full document
5
Development of antibody-based c-Met inhibitors for targeted cancer therapy
... Abstract: Signaling pathways mediated by receptor tyrosine kinases (RTKs) and their ligands play important roles in the development and progression of human cancers, which makes RTK-mediated ... See full document
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T cell receptor signaling for γδT cell development
... Studies of animals with αβTCR signaling mutations have indicated that properly controlled αβTCR signal strength is required for positive selection of immuno- competent αβT cells. The Zap70 W163C mutation in SKG ... See full document
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Insulin like growth factor signaling regulates developmental trajectory associated with diapause in embryos of the annual killifish Austrofundulus limnaeus
... All pharmacological agents were purchased from Selleck Chemicals (Houston, TX, USA). Two inhibitors of IGF receptors were used. BMS-754807 is a specific inhibitor for IGF1R (Bid et al., 2013; Carboni et al., 2009), while ... See full document
10
TrkB expression and dependence divides gustatory neurons into three subpopulations
... The timing of TrkB downregulation in the oral cavity-projecting neurons corresponds with the timing of decreased BDNF expression in the taste bud [32]. Around E14.5, geniculate neurons depend on BDNF expression in the ... See full document
13
Adenosine signaling promotes hematopoietic stem and progenitor cell emergence
... Adenosine signaling via its receptors has been studied in tissue ...adenosine signaling are expressed in the early embryo (Massé and Dale, 2012), the role of adenosine during embryogenesis, particularly at ... See full document
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CNTF/LIF/gp130 receptor complex signaling maintains a VZ precursor differentiation gradient in the developing ventral forebrain
... CNTF/LIF/gp130 signaling might operate to maintain VZ precursors, we attempted to determine the likely source of CNTF and LIF acting upon the VZ during forebrain ... See full document
14
Enzalutamide as a second generation antiandrogen for treatment of advanced prostate cancer
... androgen receptor (AR) signaling even in an androgen-deprived ...such, development of drugs that target AR and AR signaling pathways have become one of the major milestones in treatment of ... See full document
7
Androgen receptor signaling in prostate cancer development and progression
... kinase signaling cascades that target fundamental cellular processes such as proliferation and transcription ...the development and progression of many cancers, including those of the ... See full document
13
Kermit 2/XGIPC, an IGF1 receptor interacting protein, is required for IGF signaling in Xenopus eye development
... eye development To study the endogenous function of kermit 2/XGIPC in Xenopus embryos, we depleted kermit 2 using morpholino antisense ...anterior development, especially eye development, in a ... See full document
10
A Screen for Genes That Influence Fibroblast Growth Factor Signal Transduction in Drosophila
... FGF receptor (FGFR) Breathless in conjunction with downstream-of-FGF-receptor (Dof), an essential signaling molecule of the FGF pathway, in the Drosophila eye imaginal discs impairs eye ... See full document
12
Normalization of TAM post-receptor signaling reveals a cell invasive signature for Axl tyrosine kinase
... of TAM receptors in primary tumors has been associated with aggressive clinical grade, emergence of drug resistance, hallmarks of EMT, and reduced time to progression and unfavorable sur- vival outcomes in ... See full document
15
Insulin receptor signaling in the development of neuronal structure and function
... insulin receptor signaling and the structural stabilization of excitatory synaptic contacts through the association of synaptic scaffolding proteins and the ...insulin receptor plays a role in ... See full document
18
Toll Like Receptor 3 Signaling via TRIF Contributes to a Protective Innate Immune Response to Severe Acute Respiratory Syndrome Coronavirus Infection
... and signaling through TRIF, were present in ARDS patient samples as a conse- quence of the presence of infectious diseases such as H5N1 IAV and SARS-CoV infections ...cellular signaling programs resulting ... See full document
14
Postimplantation mouse development: whole embryo culture and micro manipulation
... 1987; Tam and Beddington, 1992; Parameswaran and Tam, ...1994; Tam et al., 1997a; Quinlan and Tam, unpublished) or by short-term cinemicrographic tracking of cell movement (Nakatsuji et ... See full document
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