[PDF] Top 20 The HIV 1 transmission bottleneck
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The HIV 1 transmission bottleneck
... of HIV-1 can be traced back to one or a limited number of founder ...minor HIV-1 populations in the blood of the presumed donor than to more abundant ...that transmission selects for ... See full document
19
Determinants Of Hiv-1 Transmission Fitness
... Hahn HIV-1 is predominantly transmitted by mucosal routes and almost 80 percent of new infections are initiated by a single ...eight HIV-1 donor and recipient transmission pairs ... See full document
209
Conserved Molecular Signatures in gp120 Are Associated with the Genetic Bottleneck during Simian Immunodeficiency Virus (SIV), SIV-Human Immunodeficiency Virus (SHIV), and HIV Type 1 (HIV-1) Transmission
... of transmission. A priori, one might expect different transmission routes to display different selective pres- ...with transmission were consistent in mucosal, intravenous, and breast- feeding ... See full document
11
The Genetic Bottleneck in Vertical Transmission of Subtype C HIV-1 Is Not Driven by Selection of Especially Neutralization-Resistant Virus from the Maternal Viral Population
... type 1 (HIV-1C) continues to cause the majority of new cases of mother-to-child transmission (MTCT), and yet there are limited data on HIV-1C ...19 HIV-1C MTCT pairs, 10 transmitting in ... See full document
10
Mother-to-Child HIV Transmission Bottleneck Selects for Consensus Virus with Lower Gag-Protease-Driven Replication Capacity
... Statistical analysis. The Gag-protease-driven replication capacities of viruses infecting transmitting mothers and their infants were compared by performing the paired t test for MIPs, and the Student t test was used ... See full document
16
HIV 1 envelope, integrins and co receptor use in mucosal transmission of HIV
... and transmission Upon transmission across mucosal surfaces, the HIV quasispecies replicating in an infected donor contracts through a “ genetic bottleneck ” in the recipient, and often ... See full document
10
Human Immunodeficiency Virus: The Genetic Bottleneck in Mother-to-Child Transmission
... positive HIV test within the first forty-eight hours of life are considered to have been infected in ...utero transmission of HIV, regardless of the mother’s viral load and immunologic control at ... See full document
12
Vertical Transmission of Hepatitis C Virus: Variable Transmission Bottleneck and Evidence of Midgestation In Utero Infection
... influence transmission of particular HCV ...HCV transmission, including 3 women coinfected with human im- munodeficiency virus type 1 ...regions 1 and 2, was characterized using next-generation ... See full document
19
Higher Risk of Incident Hepatitis C Virus Coinfection Among Men Who Have Sex With Men, in Whom the HIV Genetic Bottleneck at Transmission Was Wide.
... the HIV trans- mission bottleneck and the risk of acquiring an HCV coinfec- ...the transmission bottleneck was derived from the diversity detected by ...high HIV diversity indicates a ... See full document
7
Higher risk of incident Hepatitis C virus coinfection among men who have sex with men, in whom the HIV genetic bottleneck at transmission was wide
... the HIV trans- mission bottleneck and the risk of acquiring an HCV coinfec- ...the transmission bottleneck was derived from the diversity detected by ...high HIV diversity indicates a ... See full document
8
HIV-1 Envelope Glycan Moieties Modulate HIV-1 Transmission
... impact HIV-1 ...on HIV-1 transmission/infectivity. HIV-1 transmission/infectivity in vivo is highly complex; consequently, studies that utilize primary ex vivo ... See full document
10
Acyclovir and Transmission of HIV-1 from Persons Infected with HIV-1 and HSV-2
... with HIV-1 was the female ...with HIV-1 in- fection reported a median of six sexual acts with their partner in the month before ...with HIV-1, the median baseline CD4 count was ... See full document
14
Tracing HIV 1 transmission: envelope traits of HIV 1 transmitter and recipient pairs
... the transmission mode ...defined transmission pairs where viruses were derived at time points very close to the transmission ...the HIV-1 Env and that minor sequence changes can have a ... See full document
20
Surviving the Bottleneck: Transmission Mutants and the Evolution of Microbial Populations
... though transmission mutations are important only during the exponential decline in the fomite phase, they are created during the exponential growth phase, just like the growth ... See full document
8
The inference of HIV 1 transmission direction between HIV 1 positive couples based on the sequences of HIV 1 quasi species
... of HIV-1 in vivo experienced pressures from many aspects such as host’s immune system, antiretroviral therapy, which will lead to the loss of HIV diversity in vivo ...of HIV-1 positive ... See full document
8
Tetraspanins regulate cell to cell transmission of HIV 1
... Since HIV-1 accessory proteins Nef and Vpu are well-doc- umented modulators of viral infectivity and release, respectively, we also tested if their presence was required for the suppression of cell-to-cell ... See full document
13
HIV transmission. blood
... YoUr HiV stAtUs And Monitor YoUr VirAL LoAd: We cannot stress this ...without HIV if you know your status and have access to the correct ...are HIV positive can live happy, healthy and productive ... See full document
12
Selective transmission of R5 HIV 1 variants: where is the gatekeeper?
... the HIV-1 envel- ope, putative binding sites for alpha-4 beta-7 ...of transmission fitness suggest- ing that there are further gatekeepers to be ... See full document
17
HIV 1 cell to cell transmission and broadly neutralizing antibodies
... cell‑to‑cell transmission to bNAbs Infectious body fluids such as blood, semen or breast milk contain both cell-free and cell-associated HIV-1 [151, ...free HIV-1 (reviewed in ... See full document
14
Sequence Evolution of HIV-1 following Mother-to-Child Transmission
... horizontal transmission have at- tempted to estimate the extent to which intrahost sequence diversification can be attributed to immune selection pressure, most often by determining the proportion of observed ... See full document
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