[PDF] Top 20 <p>Transcriptome-Wide 5-Methylcytosine Functional Profiling of Long Non-Coding RNA in Hepatocellular Carcinoma</p>
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<p>Transcriptome-Wide 5-Methylcytosine Functional Profiling of Long Non-Coding RNA in Hepatocellular Carcinoma</p>
... adjacent non-tumor tis- sues controls were collected from HCC ...adjacent non-tumor tissue samples were obtained. RNA from each sample was isolated from cells using TRIzol reagent (Invitrogen ... See full document
9
<p>Long Non-Coding RNA PART1 Promotes Proliferation, Migration and Invasion of Hepatocellular Carcinoma Cells via miR-149-5p/MAP2K1 Axis</p>
... Background: Hepatocellular carcinoma (HCC) is the most common primary hepatic malig- nancy ...worldwide. Long non-coding RNAs (lncRNAs) and microRNAs (miRNAs) have been identi fi ed as ... See full document
12
Original Article Down-regulation of long non-coding RNA GAS5 is associated with the prognosis of hepatocellular carcinoma
... Introduction: Long non-coding RNAs (lncRNAs) have been investigated as a new class of regulators of cellular processes, such as cell growth, apoptosis, and ...in hepatocellular ... See full document
7
Original Article Overexpression of long non-coding RNA loc285194 suppresses cell proliferation and migration in hepatocellular carcinoma
... of long non-coding RNA (lncRNA) has been reported to be a new player in various diseases, including ...pathways. Hepatocellular carcinoma (HCC), with the increasing incidence, ... See full document
9
<p>Long Non-Coding RNA NEAT1 Promoted Hepatocellular Carcinoma Cell Proliferation and Reduced Apoptosis Through the Regulation of Let-7b-IGF-1R Axis</p>
... aim: Long non-coding RNA nuclear-enriched abundant transcript 1 (NEAT1) is abnormally expressed in various human malignancies, including hepatocellular carcinoma ...the ... See full document
13
Original Article Clinical implication of long non-coding RNA NEAT1 expression in hepatocellular carcinoma patients
... Abstract: Hepatocellular carcinoma (HCC), a primary malignancy of the liver, is associated with high mortality rate and poor ...novel long non-coding RNA (lncRNA), serves as a ... See full document
8
Original Article Long non-coding RNA TUG1 regulates the development of multidrug resistance in hepatocellular carcinoma via P-gp and MDR1
... of hepatocellular carcinoma (HCC), which leds to increasing resistance to different ...7.1-kb long non-coding RNA (lncRNA), was found to be up-regulated in HCC and promoted cell ... See full document
9
<p>Long Non-Coding RNA SNHG14 Contributes to the Development of Hepatocellular Carcinoma via Sponging miR-217</p>
... 1:10,000) antibodies were bought from Abcam (Cambridge, UK). HRP-conjugated secondary antibodies against rabbit (ab6721, 1:10,000) and mouse (ab205719, 1:10,000) were obtained from Abcam. Proteins were extracted from ... See full document
12
Original Article Up-regulation of long non-coding RNA Sox2ot promotes hepatocellular carcinoma cell metastasis and correlates with poor prognosis
... Hepatocellular carcinoma (HCC) is one of the most frequent human malignancies worldwide. Especially in China, it has become a major cause of cancer-related death [1]. Hepa- tocarcinogenesis is a complex ... See full document
7
<p>Upregulation of long non-coding RNA FOXP4-AS1 and its regulatory network in hepatocellular carcinoma</p>
... Results: The HCC samples had signi fi cantly higher levels of FOXP4-AS1 compared with the control (P=0.001). Six upregulated and 4 downregulated DEmiRNAs were identi fi ed. Over- and under-expressed predicted target ... See full document
14
<p>Long Non-Coding RNA EGOT Promotes the Malignant Phenotypes of Hepatocellular Carcinoma Cells and Increases the Expression of HMGA2 via Down-Regulating miR-33a-5p</p>
... cellular carcinoma (HCC). EGOT is a long non-coding RNA (lncRNA) induced after HCV infection that increases viral replication by antagonizing the antiviral ... See full document
13
Hepatitis B virus x protein induces epithelial mesenchymal transition of hepatocellular carcinoma cells by regulating long non coding RNA
... test. P < ...the functional enrichment analysis of the gene ontology (GO) and Kyoto encyclopaedia of genes and genomes (KEGG) ...GO functional terms were limited to “Biological Process” and KEGG ... See full document
9
Original Article Increased expression of long non-coding RNA TUG1 associates with poor prognosis of hepatocellular carcinoma
... All statistical analyses were performed using the software of SPSS version 18.0 for Windows (SPSS Inc, IL, USA). Student’s t test was per- formed to evaluate the difference in lncRNA TUG1 expression between HCC and ... See full document
6
Identification of long non-coding RNA-related and –coexpressed mRNA biomarkers for hepatocellular carcinoma
... of non- coding RNA transcripts longer than 200 nucleotides that were previously believed to represent transcriptional ...[4, 5], MEG3 maternally expressed 3 (MEG3) [6–8], highly upregulated in ... See full document
10
Identification of novel long non-coding RNAs deregulated in hepatocellular carcinoma using RNA-sequencing
... protein coding genes or pseudogenes in each tissue type, including in control ...of long non- coding RNA, such as DNA methylation, is particularly sensitive to the carcinogenic ... See full document
16
<p><em>SNHG16</em>: A Novel Long-Non Coding RNA in Human Cancers</p>
... nucleolar RNA host gene 16 (SNHG16), which is encoded by a 7571-bp region at chromosome ...14 hepatocellular carcinoma (HCC), 15 osteosarcoma, 16 and ... See full document
12
Identification and Functional Characterization of Long Non-coding RNA MIR22HG as a Tumor Suppressor for Hepatocellular Carcinoma
... MIR22HG and MIR22HG-mut with HuR (Figure 6C). Furthermore, HuR knockdown significantly decreased MIR22HG expression by shortening the half-life of MIR22HG in SMMC-7721 cells (Figure 6D and Figure S7E, S7F). This ... See full document
15
<p>Latest Advances of Long Non-Coding RNA SNHG5 in Human Cancers</p>
... lncRNA, long non-coding RNA; SNHG5, small nucleolar RNA host gene 5; ncRNA, non-coding RNA; miRNA, microRNA; siRNA, small interfering RNA; tRNA, ... See full document
11
<p>The role of long non-coding RNA GAS5 in cancers</p>
... also non-protein- coding genes can contribute to different ...cancer, hepatocellular carcinoma, osteosar- coma, esophageal carcinoma and pancreatic ... See full document
9
<p>Meta-analysis of the prognostic value of <em>lncRNA DANCR</em> for cancer patients in China</p>
... HCC, hepatocellular carcinoma; HTS, high tumor stage; lncRNA DANCR, long non-coding RNA anti- differentiation noncoding RNA; LNM, lymph node metastasis; LTS, larger tumor ... See full document
11
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