[PDF] Top 20 Transfusion strategy in hematological intensive care unit: study protocol for a randomized controlled trial

... (PRBC) transfusion is required in hematology patients treated with chemotherapy for acute leukemia, autologous (auto) or allogeneic (allo) hematopoietic stem cell transplantation ...restrictive transfusion ... See full document

... validated strategy for the timing of renal replacement therapy (RRT) for acute kidney injury (AKI) in the intensive care unit (ICU) when short-term life-threatening metabolic abnormalities are ... See full document

... Heart rate, blood pressure, and body temperature will be documented hourly for the first 24 h after treat- ment start and every 12 h thereafter in both treat- ment groups, and additionally at every dose change of ... See full document

... blood unit cost of £200, assuming that an average of two units are transfused when given, if ...reduces transfusion rates from 38% to 25%, the direct cost saving in transfusion-related costs is ... See full document

... blood unit cost of £200, assuming that an average of two units are transfused when given, if ...reduces transfusion rates from 38% to 25%, the direct cost saving in transfusion-related costs is ... See full document

... the intensive care unit (ICU), in the emergency depart- ment (ED), or during in-hospital emergency in general wards ...backup strategy if required, and deficiency in available equipment, all ... See full document

... the study was not powered to adequately explore this ...the study in a single unit, and use of a combination of three compounds in the chlorhexidine arm all constituted ob- stacles to generalization ... See full document

... taking care of newborn infants, which is often gained in families with multiple children through taking care of younger ...Chinese study [13] reported that mothers ex- perience a lot of anxiety when ... See full document

... Our protocol builds on prior research as the anxiolytic properties of music have been well documented ...our protocol include blinding of outcome assessors, twice daily delir- ium assessments, as well as ... See full document

... addition, care for the invasively ventilated ICU patient has changed significantly over the last ...in care may have resulted in an increased ability of invasively ven- tilated ICU patients to clear their ... See full document

... Every attempt will be made to collect full follow-up data on all women (unless a woman withdraws consent for follow-up data collection). In particular, women will be followed up even after protocol violation. It ... See full document

... the study dose is inexpensive (less than 40 Canadian dollars per surgical case), technically easy to administer, and has been successfully performed in several trials evaluating other surgical ...a study of ... See full document

... The sample size of the present trial was estimated using a statistical software (G*Power 3 for Macintosh). The change in serum levels of C-reactive protein was consid- ered the main outcome for sample size ... See full document

... individually randomized trials, the concept of clinical equipoise helpfully frames questions regarding researcher obligations to subjects in the control group and when data monitoring committees ought to recommend ... See full document

... fusion strategy is supported by the most current, high-quality evidence ...RBC transfusion event) for whom a restrictive transfu- sion strategy has not been proven safe, nor superior, to a liberal ... See full document

... Previous randomized controlled trials reported that dexmedetomidine might attenuate renal injury during the perioperative period in patients who underwent car- diac surgery ...no randomized ... See full document

... residential care in improving emotional resilience and in reducing (future) depressive symptoms, this may lead to better general outcomes of residential treatment on general ...youth care settings in the ... See full document

... the study will obtain consent from patients that meet the inclusion and exclu- sion criteria, and also from parents for patients under 18 years of ...the study termination point and will be ... See full document

... COCOA Study is a prospective, pragmatic, pilot randomized controlled trial ...COCOA Trial, we are enrolling approximately 120 parti- cipants 65 years old or older who report subacute or ... See full document

... Considering the reduction in the risk of preterm delivery by the pessary described by the PECEP clinical trial [27], and considering our own outcomes in women with a short cervix, we anticipate a composite poor ... See full document