[PDF] Top 20 Treatment of acute diverticulitis laparoscopic lavage vs resection (DILALA): study protocol for a randomised controlled trial

... retrospective study at the Sahlgrenska University Hospital, Gothenburg studied all patients (n = 106) admitted and operated for complicated diverticulitis between 2003 and 2008 ... See full document

... Extralesional excision is performed with minimal mar- gins, and absorbable monofilament sutures or perman- ent monofilament sutures are used for closure (Monocryl™, Ethilon™, Ethicon Inc, Somerville, NJ, USA). Surgery is ... See full document

... The most widely used cost-effective emergency treat- ment is intravenous (IV) thrombolysis using recombin- ant tissue plasminogen activator for selected ischaemic stroke cases within 4.5 h of symptom onset [3]. Despite ... See full document

... logical treatment; and they should not be suffering from clinical or sub-clinical anxiety symptoms, if the patient is undergoing any medical treatment for their condition, the dosage has to be stable for at ... See full document

... Negative symptomatology will be assessed using the SANS. The SANS scale is expected to have a pooled standard deviation of 13 points [5]. Given a sample size of 63 per group and a two-sided alpha of 0.05, we have 80% ... See full document

... overall study population, assuming an effect that leads to a 7% absolute risk reduction (ARR) in poor functional outcome (mRS 3 to 6) in the GTN group compared with controls (48% vs ...simulation ... See full document

... Suboptimal acute pain management in SCD patients is associated with caregivers' preoccupation with the pathophysiological causes of vaso-occlusion and concern of creating opioid dependence [9], and a negative ... See full document

... be controlled for in analysis: standard demographics; tumour site, stage and response; pro- posed and delivered concurrent chemotherapy; concur- rent surgery; number and frequency of dietetic consults; unplanned ... See full document

... the trial on safety rules or efficacy ...the trial for effi- cacy reasons: i.e. to consider stopping the trial early be- cause of efficacy, a p-value < ...the study and con- trol groups and ... See full document

... RhIL-11 is produced by recombinant DNA technology in Escherichia coli, which has shown effects on multiple hematopoietic cell types. And rhIL-11 could induce mega- karyocyte maturation and stimulate megakaryocyte to in- ... See full document

... proposed study is that it is one of the first studies examining a program to increase emotional resilience in a residential setting and is also the only Dutch CBT program specifically adapted to adolescents with ... See full document

... the study was antici- pated to be challenging due to the narrow recruitment window between the decision to have ECT and the first ...the study itself, three ECT suites have closed due to NHS Trust ... See full document

... Although delineated from suicidal behaviour by defin- ition, people who repeatedly self-injure carry a fourfold risk of suicidal thoughts and behaviours within the following year [7], and are 42 times more likely to at- ... See full document

... liver resection in terms of time to functional recovery, length of hospital stay (LOS), long-term abdominal wall hernias, costs and quality of life (QOL) has never been studied in a randomised ... See full document

... scopic lavage is associated with an increased severe morbidity within 90 days from the ...the treatment, as highlighted by the significative higher incidence of intra-abdominal abscess as a conse- quence of ... See full document

... the study results may be difficult to ...the trial. Second, because of the ethic concern, group with- out lavage at all can not be set up in China to investigate its role in OP patients ...single ... See full document

... this treatment, and it is unclear what determines individual differences in ...pilot study is to examine feasibility of a design to test hypotheses focusing on an unselected sample, that is, without ... See full document

... the study, the feasibility of both techniques will be confirmed by diagnostic laparoscopy to avoid inclusion of patients who are immediately con- verted to open ...for diverticulitis. Based on the ... See full document

... from acute abdominal pain but who were not diagnosed after first consultation, the diagnostic process could be ...this randomised controlled trial is to study whether supporting faecal ... See full document

... retrospective study showed lower mortality in eld- erly ACC patients who received cholecystectomy in the same admission compared to those managed conserva- tively ...tive treatment for mild ACC in the ... See full document