[PDF] Top 20 Uncoupling protein 2 gene polymorphisms are associated with obesity
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Uncoupling protein 2 gene polymorphisms are associated with obesity
... This study provided evidence concerning the role of UCP 2 gene polymorphisms in influencing the increasing preva- lence of obesity. Moreover, this study has the advantage of being conducted in ... See full document
10
The Deletion Polymorphism in Exon 8 of Uncoupling Protein 2 is Associated with Severe Obesity in a Saudi Arabian Case-Control Study
... previously associated with lower resting metabolic and energy expenditure rates in young adults, and thus postulated to contribute to the development of obesity at a later age ...of obesity revealed ... See full document
5
Effects of mutations in the human uncoupling protein 3 gene on the respiratory quotient and fat oxidation in severe obesity and type 2 diabetes
... two polymorphisms exclusively in African Americans with allele frequencies of 18% (V102I) and 10% (exon ...When obesity- and Type 2 Diabetes– related quantitative traits were assessed, heterozygotes ... See full document
8
The uncoupling protein 1 gene, UCP1, is expressed in mammalian islet cells and associated with acute insulin response to glucose in African American families from the IRAS Family Study
... between uncoupling protein polymorphisms (UCP2-UCP3) and energy metabo- lism/obesity in Pima ...the uncoupling protein 2 gene on 24-h energy expenditure and ... See full document
10
Complex Relationship between Obesity and the Fat Mass and Obesity Locus
... Fourteen obesity-susceptibility genes were analyzed in this survey, and PA can greatly alleviate the genetic effect of ...of obesity-predisposing SNPs on PA revealed novel associations; however, further ... See full document
15
FTO gene polymorphisms and obesity risk: a meta-analysis
... was associated with BMI, total body weight, and hip circumference; many variants have been reported to be associated with obesity, includ- ing rs9939609, rs1421085, rs8050136, rs17817449, and ... See full document
15
Vitamin D pathway gene polymorphisms, diet, and risk of postmenopausal breast cancer: a nested case control study
... or associated polymorphisms in the 3' region and breast cancer risk is in contrast to findings in five studies that reported increased risk of breast cancer, mostly among Caucasian women with the bb ... See full document
7
<p><em>FTO</em> Polymorphisms are Associated with Metabolic Dysfunction-Associated Fatty Liver Disease (MAFLD) Susceptibility in the Older Chinese Han Population</p>
... 5mL of peripheral venous blood were collected from each subject. Then, the genomic DNA was extracted using the standard phenol-chloroform method for genotyping. SNPs were selected based on positive reported variants for ... See full document
9
Uncoupling proteins, dietary fat and the metabolic syndrome
... Interestingly, the same UCP2 -866G/A polymorphism and a -55C/T polymorphism in UCP3 are both associated with significantly reduced prevalence of diabetic neurop- athy in type-1 diabetics [51]. Presumably these ... See full document
7
Association Between Uncoupling Protein 3 Gene and Obesity-Related Phenotypes in the Québec Family Study
... UCP3 gene from subjects homozygote for either GAIVS6 238 bp or 240 bp alleles were sequenced in search for mu- ...not associated to adiposity in QFS; V102I(G→A) showed no ... See full document
9
Fto Deficiency Reduces Anxiety- and Depression-Like Behaviors in Mice via Alterations in Gut Microbiota
... and obesity- associated gene; CUMS: chronic unpredictable mild stress; SNPs: single-nucleotide polymorphisms; BAT: brown adipose tissue; WAT: white adipose tissue; MDD: major depressive ... See full document
13
Milk: an epigenetic amplifier of FTO mediated transcription? Implications for Western diseases
... been associated with T2DM. CpG methylation is generally associated with gene ...been associated with excessive miRNA-29 expression of dairy cow mammary epithelial cells ...that obesity, ... See full document
22
Uncoupling protein 2 polymorphisms as risk factors for NTDs
... UCP2 polymorphisms in energy metabolism, obesity, and type-2 ...and obesity in some studies (Marti et ...been associated with a modest increased risk for obesity in a Caucasian ... See full document
10
Common Variations in Perilipin rs1052700 and FTO rs3751812 Genes, Central Obesity, and Risk Type-2 Diabetes
... Type 2 diabetes is recognized when any of the following criteria are met: FBG ≥ 126 mg/dL ...mmol/L), 2-hour plasma glucose ≥ 200 mg/dL ...However, obesity and T2D are increasing ...on ... See full document
8
Uncoupling protein 2 G(-866)A polymorphism: a new gene polymorphism associated with C-reactive protein in type 2 diabetic patients C-reactive protein in type 2 diabetic patients
... X 2 goodness-of-fit test was used to assess deviation from Hardy-Weinberg equilibrium of the genotypic frequency by calculating expected fre- quencies of ...X 2 square ... See full document
5
Original Article High-sensitivity C-reactive protein (hs-CRP) gene polymorphisms (rs1205 and rs2794520) associated with hs-CRP serum levels in periodontitis-associated chronic kidney disease patients from Uyghur adults
... Chronic periodontitis is an inflammatory dis- ease and is a predominantly Gram-negative infection of the oral cavity that seriously endan- gers the tooth structure, including destruction of periodontal ligament and ... See full document
12
Polymorphisms of the mannose binding lectin (MBL2) gene are related to protein plasma levels but not with visceral leishmaniasis in a northeastern brazilian population
... MBL2 polymorphisms within the structural gene as well as the promoter region influence functional MBL serum levels but are not associated with susceptibility to ...MBL 2 polymorphisms ... See full document
12
<p>Polymorphisms of the <em>NLRC4</em> Gene are Associated with the Onset Age, Positive Rate of GADA and 2-h Postprandial C-Peptide in Patients with Type 1 Diabetes</p>
... as protein tyrosine phosphatase antibody (IA-2A), glutamic acid decarboxylase antibody (GADA) and zinc transporter 8 antibody ...and 2-h postprandial plasma glucose (PPG) < ... See full document
8
Expression of the mitochondrial uncoupling protein gene from the aP2 gene promoter prevents genetic obesity
... aP2 gene promoter directed Ucp expression in white fat and provided for the constitutive expression of Ucp in brown ...at 2-10% the level normally measured in brown ...endogenous gene expression by ... See full document
11
Original Article Relationship between CTLA-4 +49A>G polymorphism and the risk of lung adenocarcinoma in a Chinese Han population
... transmembrane protein on the activated T-cell ...have associated CTLA-4 +49A>G polymorphism with certain cancers, but the associations with lung cancer have been ...was associated with an ... See full document
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