[PDF] Top 20 Understanding Acute Lymphoblastic Leukaemia
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Understanding Acute Lymphoblastic Leukaemia
... It is important to remember that you may not be suitable for it. The type of leukaemia, your age, medical history and viral status can affect your suitability. Your doctor will arrange for you to have a blood test ... See full document
41
Nutritional Assessment and Serum Zinc Level in Children with Acute Lymphoblastic Leukaemia
... Result: Majority (80%) of the cases and 60% of the controls were 5 or < 5 years old. The mean ages of the children of cases and controls were almost similar (4.2 ± 2.3 vs. 4.8 ± 1.8 years, p >0.05). The groups were ... See full document
5
The subclonal complexity of STIL-TAL1+ T-cell acute lymphoblastic leukaemia.
... Despite these caveats, several informative conclusions can be drawn. A consistent feature is that STIL-TAL1 fusion and CDKN2A loss are both early or truncal events, in contrast to other recurrent genetic changes ... See full document
10
The Role of MicroRNA in Paediatric Acute Lymphoblastic Leukaemia: Challenges for Diagnosis and Therapy.
... in leukaemia, intracellular miR-210 levels were altered by transfecting two different paediatric ALL cell lines (ETV6-RUNX1+ Reh and MLL-AF4+ RS4;11) with an agomiR and antagomiR to miR-210 ...to leukaemia ... See full document
15
Cytogenetic and molecular aberrations in childhood B lineage acute lymphoblastic leukaemia
... Background: Acute Lymphoblastic Leukemia (ALL) is a common hematological malignancy in children and is characterized by genetic changes such as mutations and chromosomal ... See full document
5
Longitudinal assessment of nutritional status and its effects on the outcome of children completed treatment for Acute Lymphoblastic Leukaemia.
... Childhood leukaemia survivors are at risk for several possible late effects of the disease or ...have leukaemia after 10 years of age had low mean 5 year EFS(event free survival) and increased risk of ... See full document
152
Abnormalities of chromosome 9p in lymphoid malignancies
... Analysis here of 231 primary tumours showed that biallelic deletions of occurred in 18% of B-cell precursor acute lymphoblastic leukaemia (BCP-ALL) and in some high [r] ... See full document
215
Hypereosinophilia in childhood acute lymphoblastic leukaemia at diagnosis: report of 2 cases and review of the literature
... 12. Conter V, Bartram CR, Valsecchi MG, Schrauder A, Panzer-Grümayer R, Möricke A, Aricò M, Zimmermann M, Mann G, De Rossi G, Stanulla M, Locatelli F, Basso G, Niggli F, Barisone E, Henze G, Ludwig WD, Haas OA, Cazzaniga ... See full document
5
The Developmental Pathways of Preschool Children with Acute Lymphoblastic Leukemia: Communicative and Social Sequelae One Year after Treatment
... with leukaemia can also be influenced by HSCT, with a decline in motor and mnemonic abilities within the first year post-HSCT [(1)] and in verbal skills, with arithmetic and motor scores attested below the norms ... See full document
16
Growth impairment after TBI of leukemia survivors children: a model- based investigation
... childhood lymphoblastic and myeloid acute leukaemia survivors followed at Pediatric Onco-Hematology, Stem Cell Transplantation and Cellular Therapy Division, Regina Margherita Children ’ s Hospital ... See full document
11
Genetic and regulatory mechanism of susceptibility to high-hyperdiploid acute lymphoblastic leukaemia at 10p21.2.
... Despite high-hyperdiploid acute lymphoblastic leukaemia (HD-ALL) being the most common subgroup of paediatric ALL, its aetiology remains unknown. Genome-wide association studies have demonstrated ... See full document
9
Determination of the DNA repair pathways utilised by acute lymphoblastic leukaemia cells following daunorubicin treatment
... Factors influencing choice between NHEJ and HR are still unclear as many factors influence these processes including MRN complex, cell cycle checkpoints, and DNA-DSB effector proteins [14]. The aim of this study was to ... See full document
5
Effect of dexamethasone on quality of life in children with acute lymphoblastic leukaemia: a prospective observational study
... Acute Lymphoblastic Leukaemia (ALL) is the most com- mon form of childhood cancer. Over the past decades sur- vival following treatment for childhood ALL has improved substantially, now reaching ... See full document
8
Analysis of ZAP70 expression in adult acute lymphoblastic leukaemia by real time quantitative PCR
... adult acute lymphoblastic leukemia (ALL): analysis of cytogenetic data from patients treated on the Medical Research Council (MRC) UKALLXII/Eastern Cooperative Oncology Group (ECOG) 2993 ... See full document
5
Third-generation CD28/4-1BB chimeric antigen receptor T cells for chemotherapy relapsed or refractory acute lymphoblastic leukaemia: a non-randomised, open-label phase I trial protocol
... Introduction: There is no curative treatment available for patients with chemotherapy relapsed or refractory CD19+ B cells-derived acute lymphoblastic leukaemia (r/r B-ALL). Although CD19-targeting ... See full document
7
Population pharmacokinetics of teicoplanin and attainment of pharmacokinetic/pharmacodynamic targets in adult patients with haematological malignancy
... Demographic and clinical details of the included patients n=30a Characteristic Male sex 14 46.7 Age years 64 [14] Haematological malignancy diagnosis Acute lymphoblastic leukaemia 1 3.3 [r] ... See full document
23
French “real life” experience of clofarabine in children with refractory or relapsed acute lymphoblastic leukaemia
... able leukaemia cells in peripheral blood, M1 bone marrow (≤ 5% blasts) and recovery of peripheral counts (platelets ≥ 100 x 10 9 /l and an absolute granulocyte count (ANC) ≥ ... See full document
8
Study of fingerprints in children under 15 years of age with acute lymphoblastic leukaemia
... frequency of arches was same, about 6.3% in both cases and controls. The findings for association were not found to be statistically significant (P>0.05), but it is suggestive of the finding that children with higher ... See full document
5
Acute disseminated encephalomyelitis mimicking late CNS relapse of acute lymphoblastic leukaemia: case report
... severe acute myelopathy and ...an acute lymphoblastic leukaemia, treated with allogeneic bone marrow ...her leukaemia. The diagnosis was acute disseminated ... See full document
5
Analysis of NEIL3 expression : a possible resistance factor to cancer chemotherapy in paediatric cancer cells
... Gene expression of NEIL3, hTERT and POT1 was measured by qRT-PCR in two cell lines of acute lymphoblastic leukaemia ALL; steroid sensitive and steroid resistant cells, osteosarcoma, hepa[r] ... See full document
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