[PDF] Top 20 Update on the clinical utility and optimal use of cefditoren
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Update on the clinical utility and optimal use of cefditoren
... new clinical studies of cefditoren in the treatment of pharyngotonsillitis, sinusitis, and otitis media in children, mainly in Japan, support the adequacy of cefditoren for the treatment of these ... See full document
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Update on the clinical utility of an RNA interference-based treatment: focus on Patisiran
... In addition to speeding up the functional validation of gene lists from association-based pharmacogenomics data, high-throughput screening strategies for genome-scale func- tional analysis can potentially be a more ... See full document
12
An update on the clinical utility of extracorporeal photopheresis in the treatment of graft-versus-host disease
... earlier use of ECP in the course of cGVHD, thus offering better control of GVHD and subsequently minimizing the risk of irreversible tissue damage and risk of death from systemic infections secondary to prolonged ... See full document
10
Update on the optimal use of voriconazole for invasive fungal infections
... oral voriconazole dose was 6 mg/kg, and patients receiving intravenous treatment had a median dose of 7.5 mg/kg/day. This raises an important point regarding dosing of vori- conazole, as the package insert for ... See full document
11
An update on clinical utility of rilpivirine in the management of HIV infection in treatment-naïve patients
... Use of once-daily ART is one strategy to improve adher- ence in HIV patients. Tenofovir/emtricitabine/efavirenz (TDF/FTC/EFV) is a well-tolerated option for single-tablet regimens (STRs). The STaR study aimed to ... See full document
11
Update on optimal use of omalizumab in management of asthma
... Evaluating Clinical Effectiveness and Long-Term Safety in Patients With Moderate to Severe Asthma) is evaluating the long-term safety profile of omalizumab in patients followed for 5 ...the use of ... See full document
11
Clinical utility and patient considerations in the use of the sitagliptin-metformin combination in Chinese patients
... the clinical char- acteristics and manifestations of DM in Chinese patients are different from those in Western ...an optimal treatment protocol for lowering blood glucose levels in Chinese patients with ... See full document
7
Update and clinical utility of the LenSx femtosecond laser in cataract surgery
... for use during cataract ...and clinical results relating to capsulotomy, phacoemulsi- fication and lens fragmentation, corneal wound creation, and visual ... See full document
9
Update on pulmonary arterial hypertension in children: management strategies and clinical utility of sildenafil
... Abstract: Pulmonary hypertension is an area of growing interest in cardiology, respiratory, and rheumatic diseases due to the increased treatment that is now available to ameliorate the disease process and the improved ... See full document
9
Update on the clinical use of buprenorphine
... lowed for 6 months with optimal adjustments of dos- ing. Both arms had a similar retention rate (78%). In the buprenorphine-naloxone group, 46% of those who com- pleted the study had continued taking buprenorphine ... See full document
5
Clinical utility and patient considerations in the use of ofatumumab in chronic lymphocytic leukemia
... cohort of heavily pretreated CLL patients were categorized as fludarabine-alemtuzumab refractory (FA-ref; 95 at the final analysis) and bulky-fludarabine refractory (BF-ref; 112 at the final analysis). Only 51% of ... See full document
12
Update on the role of candesartan in the optimal management of hypertension and cardiovascular risk reduction
... Candesartan, a long-acting antihypertensive agent, has been shown to have a more efficacious antihypertensive activity than other ARBs such as losartan, and it effectively combines with other antihypertensive agents such ... See full document
11
Update and clinical utility of alcaftadine ophthalmic solution 0.25% in the treatment of allergic conjunctivitis
... pharmacokinetics, clinical trials, clinical efficacy, and safety of ...the clinical utility of alcaftadine in allergic ...pharmacokinetics, clinical trials, and clinical efficacy ... See full document
11
Critical appraisal and update on the clinical utility of agomelatine, a melatonergic agonist, for the treatment of major depressive disease in adults
... Agomelatine is metabolized primarily by CYP-1A2 enzyme in the liver, with lesser metabolic contributions from CYP-2C9/2C19. Based on this, the use of agomelatine is contraindicated in patients taking drugs ... See full document
14
Update on the clinical utility and practical use of ropivacaine in Chinese patients
... Ropivacaine is a well-tolerated local anesthetic that is effec- tive when administered as a peripheral nerve or ocular block, epidural or spinal block, or by topical application or local infiltration. In comparative ... See full document
8
Update on the clinical utility of sildenafil in the treatment of pulmonary arterial hypertension
... anorexigen use, or connec- tive tissue disease, sildenafil treatment results in improved exercise capacity as measured by 6 minute walk distance, improved hemodynamics, and favorable changes in quality of ... See full document
10
Update on optimal use of lisdexamfetamine in the treatment of ADHD
... LDX use, just as with other stimulant ...intravenous use; as a result, LDX may have somewhat less potential for abuse and ...fact clinical trials comparing LDX with OROS (osmotic controlled-release ... See full document
7
Update on the optimal use of bortezomib in the treatment of multiple myeloma
... its use quickly spread to the newly diag- nosed transplant-eligible and transplant-ineligible setting, and it is now considered an important backbone therapy for all stages of the ...its use in Waldenstrom ... See full document
13
Clinical Utility Gene Card for Trimethylaminuria update 2014
... 2.5 Positive clinical predictive value life-time risk to develop the disease if the test is positive All those identified as homozygous or compound heterozygous for sequence variants that[r] ... See full document
5
Update on the use of dutasteride in the management of benign prostatic hypertrophy
... for use in the treatment of men with symptomatic ...The use of this drug is contraindicated in men under age 18 and in women due to the potential adverse effects on normal de- velopment of the male ... See full document
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