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[PDF] Top 20 Utility of Human Immunodeficiency Virus Type 1 Envelope as a T-Cell Immunogen

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Utility of Human Immunodeficiency Virus Type 1 Envelope as a T-Cell Immunogen

Utility of Human Immunodeficiency Virus Type 1 Envelope as a T-Cell Immunogen

... Gag T-cell epitopes. Mu- tations at CD8 T-cell epitopes may produce viral populations with reduced replication ...tant virus implies effective elimination of WT virus by CD8 ... See full document

10

Induction of T-Cell Immunity to Antiretroviral Drug-Resistant Human Immunodeficiency Virus Type 1

Induction of T-Cell Immunity to Antiretroviral Drug-Resistant Human Immunodeficiency Virus Type 1

... CD8 T-cell responses as previously described (9, ...of 1 ␮ g/ml/peptide in the presence of costimu- latory antibodies to CD28 and ...with Cell Quest ...) T lymphocytes expressing IFN-␥ ... See full document

10

Multiple T-Cell Responses to Human Immunodeficiency Virus Type 1 Are Enhanced by Dendritic Cells

Multiple T-Cell Responses to Human Immunodeficiency Virus Type 1 Are Enhanced by Dendritic Cells

... to T cells (2). Indeed, it is likely that during HIV-1 infection, DC are required to take up, process, and present HIV-1 antigens via their major histocompatibility com- plex (MHC) class I and II ... See full document

14

Reduced cell surface expression of processed human immunodeficiency virus type 1 envelope glycoprotein in the presence of Nef.

Reduced cell surface expression of processed human immunodeficiency virus type 1 envelope glycoprotein in the presence of Nef.

... 3274-3280 0022-538X/93/063274-07$02.00/0 Copyright 1993, American Society for Microbiology Reduced Cell Surface Expression of Processed Human Immunodeficiency Virus Type 1 Envelope Glyc[r] ... See full document

7

Transfer of Specificity for Human Immunodeficiency Virus Type 1 into Primary Human T Lymphocytes by Introduction of T-Cell Receptor Genes

Transfer of Specificity for Human Immunodeficiency Virus Type 1 into Primary Human T Lymphocytes by Introduction of T-Cell Receptor Genes

... vaccinia virus Gag or with a control vaccinia virus immediate-early recombinant expressing the 72- kDa immediate-early protein from cytomegalovirus ...epitope. T cells expressing an in- termediate ... See full document

6

Replicative function and neutralization sensitivity of envelope glycoproteins from primary and T-cell line-passaged human immunodeficiency virus type 1 isolates.

Replicative function and neutralization sensitivity of envelope glycoproteins from primary and T-cell line-passaged human immunodeficiency virus type 1 isolates.

... oligomeric envelope glyco- protein complexes and to induce the dissociation of the gp120 glycoprotein from these complexes (29, 38) was examined by incubating radiolabeled COS-1 cells expressing the ... See full document

10

Characterization of Envelope Glycoprotein Mutants for Human T-Cell Leukemia Virus Type 1 Infectivity and Immortalization

Characterization of Envelope Glycoprotein Mutants for Human T-Cell Leukemia Virus Type 1 Infectivity and Immortalization

... and envelope protein expression of ACH-envelope clones. (A and B) Cell lysates (A) and virions released into supernatants (B) from pACH-transfected 293T cells (lanes 1 to 9, as indicated), ... See full document

7

Limited Breadth of a T-Helper Cell Response to a Human Immunodeficiency Virus Envelope Protein

Limited Breadth of a T-Helper Cell Response to a Human Immunodeficiency Virus Envelope Protein

... 120 cell supernatants) and rat anti-mouse CD8 (53-6.72 cell supernatants) ...Norway). Cell samples were exposed to a magnet to remove MHC class II-positive, CD8-positive, and Ig-positive ...depleting ... See full document

6

Tightly bound zinc in human immunodeficiency virus type 1, human T-cell leukemia virus type I, and other retroviruses.

Tightly bound zinc in human immunodeficiency virus type 1, human T-cell leukemia virus type I, and other retroviruses.

... Other retroviruses, including simian immunodeficiency virus, equine infectious anemia virus, bovine leukemia virus, Moloney murine leukemia virus, mouse mammary tumor virus, and Mason-Pf[r] ... See full document

8

Transdominant repressors for human T-cell leukemia virus type I rex and human immunodeficiency virus type 1 rev function.

Transdominant repressors for human T-cell leukemia virus type I rex and human immunodeficiency virus type 1 rev function.

... The rex genes encoded by the mutant clones pLHRexM2, pLHRexM7, and pLHRexM8 were able to inhibit wild-type function of the HIV-1 Rev protein Fig.. The expression of Rev was Mnonitored by[r] ... See full document

8

Envelope-Dependent Restriction of Human Immunodeficiency Virus Type 1 Spreading in CD4+ T Lymphocytes: R5 but Not X4 Viruses Replicate in the Absence of T-Cell Receptor Restimulation

Envelope-Dependent Restriction of Human Immunodeficiency Virus Type 1 Spreading in CD4+ T Lymphocytes: R5 but Not X4 Viruses Replicate in the Absence of T-Cell Receptor Restimulation

... presence of 0.4 mM primer pairs (PRIMM S.p.A., Milan, Italy), 200 mM con- centrations of the deoxynucleoside triphosphates (Pharmacia Biotech), 1⫻ PCR buffer, and 1.25 U of AmpliTaq Gold DNA polymerase ... See full document

9

Stoichiometry of Monoclonal Antibody Neutralization of T-Cell Line-Adapted Human Immunodeficiency Virus Type 1

Stoichiometry of Monoclonal Antibody Neutralization of T-Cell Line-Adapted Human Immunodeficiency Virus Type 1

... in 1⫻ Novex LDS sample buffer containing 1⫻ reducing agent ...(Novex). Cell lysates and virion-depleted supernatants were ad- justed to contain 1⫻ LDS sample buffer and reducing agent before ... See full document

7

Processing of the envelope glycoprotein gp160 in immunotoxin-resistant cell lines chronically infected with human immunodeficiency virus type 1.

Processing of the envelope glycoprotein gp160 in immunotoxin-resistant cell lines chronically infected with human immunodeficiency virus type 1.

... incubating cell pellets in ...NaCl, 1% Nonidet P-40) for 15 min on ice. Nuclei and cell debris were removed by centrifugation, and protein concentrations were determined with the BCA Protein Assay ... See full document

10

A semiquantitative assay for CD8+ T-cell-mediated suppression of human immunodeficiency virus type 1 infection.

A semiquantitative assay for CD8+ T-cell-mediated suppression of human immunodeficiency virus type 1 infection.

... ciency virus type 1 (anti-HIV-1) suppressive activity of CD8 1 T ...CD8 1 T ...CD8 1 T cells was consistently demonstrable with both endogenously ... See full document

7

Human immunodeficiency virus type 1 T-cell tropism is determined by events prior to provirus formation.

Human immunodeficiency virus type 1 T-cell tropism is determined by events prior to provirus formation.

... Use of a molecularly cloned primary HIV-1 isolate, HIV-lJR-CSF, restricted for replication in T-cell lines, demonstrated that little or no viral DNA or RNA was synthesized in nonpermissi[r] ... See full document

8

Determinants of human immunodeficiency virus type 1 envelope glycoprotein oligomeric structure.

Determinants of human immunodeficiency virus type 1 envelope glycoprotein oligomeric structure.

... simian immunodeficiency virus env glycoprotein precursors are functionally conserved, since heterodimers of the env glyco- protein precursors form when they are coexpressed in the same cell ... See full document

10

Reevaluation of the Requirement for TIP47 in Human Immunodeficiency Virus Type 1 Envelope Glycoprotein Incorporation

Reevaluation of the Requirement for TIP47 in Human Immunodeficiency Virus Type 1 Envelope Glycoprotein Incorporation

... the human immunodeficiency virus type 1 (HIV-1) envelope glycoproteins into assembling particles is crucial for virion ...protein 1), a member of the perilipin, ... See full document

10

A Recombinant Sendai Virus Is Controlled by CD4+ Effector T Cells Responding to a Secreted Human Immunodeficiency Virus Type 1 Envelope Glycoprotein

A Recombinant Sendai Virus Is Controlled by CD4+ Effector T Cells Responding to a Secreted Human Immunodeficiency Virus Type 1 Envelope Glycoprotein

... least 1 month after the completion of immunizations, spleens from control and test mice were taken for CD4 ⫹ T-cell ...depleting T cells with an anti-mouse Thy1.2 (AT83) and complement ... See full document

8

Effects of Antiretroviral Drugs on Human Immunodeficiency Virus Type 1-Induced CD4+ T-Cell Death

Effects of Antiretroviral Drugs on Human Immunodeficiency Virus Type 1-Induced CD4+ T-Cell Death

... uninfected T lymphocytes and polymorphonuclear leuko- cytes, suggesting that HIV protease inhibitors may improve im- mune function by reducing induction of apoptosis (34, 45, 50, ...monitored T-cell ... See full document

8

Oligomeric Structure of the Human Immunodeficiency Virus Type 1 Envelope Protein on the Virion Surface

Oligomeric Structure of the Human Immunodeficiency Virus Type 1 Envelope Protein on the Virion Surface

... The envelope protein (Env) of human immunodeficiency virus type 1 (HIV-1) mediates functions that are critical to the viral life cycle, including viral attachment to ... See full document

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