[PDF] Top 20 Variants in multiple genes polymorphism association analysis of COPD in the Chinese Li population
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Variants in multiple genes polymorphism association analysis of COPD in the Chinese Li population
... The Chinese Li minority population-based case–control study comprising COPD patients diagnosed from January 2010 to December 2013 from the Hainan Province People’s Hospital was ...were ... See full document
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The association analysis of hOGG1 genetic variants and gastric cancer risk in a Chinese population
... meQTL analysis. The rs125701 polymorphism is located adjacent to the CpG site of cg15357639, which is able to undergo ...of genes’ methylation and contribute to tumorigenesis in turn [34– ...nearby ... See full document
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Pathogenic variants screening in seventeen candidate genes on 2p15 for association with ankylosing spondylitis in a Han Chinese population
... major genes on chromosome 2p15 area as candidate genes, with 12 SNPs being identified to be the potentially functional genetic variants for ...stratification analysis by gender fur- ther ... See full document
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Original Article Meta-analysis on the association between CYP1A1 T3801C polymorphism and breast cancer in the Chinese population
... responsible genes. Since the first negative association between CYP1A1 T3801C and BC was reported [6], many studies have been undertaken to investigate the ...significant association between CYP1A1 ... See full document
7
Association of CYP1A1 MspI polymorphism in the esophageal cancer risk: a meta-analysis in the Chinese population
... The pathways of carcinogen metabolism are complex, mediated by the activity of multiple enzymes. The effect of any single gene might have a limited impact on EC risk than have so far been anticipated. EC has some ... See full document
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The association analysis of lncRNA HOTAIR genetic variants and gastric cancer risk in a Chinese population
... Recently, considerable studies have investigated the effects of lncRNAs genetic variations (majorly composed of single nucleotide polymorphisms, SNPs) on cancer susceptibility. The tagging SNP (tagSNP) rs2839698 of ... See full document
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Association of lncRNA H19 rs217727 polymorphism and cancer risk in the Chinese population: a meta-analysis
... genetic variants of lncRNA H19 have been shown to affect its expression and susceptibility to cancers [13, ...the association between the lncRNA H19 rs217727 polymorphism and cancer risk, which might ... See full document
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Population-based study of the association of variants in mismatch repair genes with prostate cancer risk and outcomes.
... One limitation to this study is possible type I error due to multiple testing. For each of the 19 SNPs, we calculated 6 significance tests among Caucasians, so one would expect about 6 results might be due solely ... See full document
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Original Article X-ray repair cross-complementing protein 1 polymorphisms and risk of nasopharyngeal carcinoma: a meta-analysis in the Chinese population
... the Chinese population speci- fically, in order to reduce the impact of genetic ...meta- analysis, we found that XRCC1 Arg399Gln polymorphism might be a low penetrant risk factor for NPC in ... See full document
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Association between the interleukin-1β C-511T polymorphism and periodontitis: a meta-analysis in the Chinese population.
... candidate genes have been identified as potential periodontitis susceptibility ...these genes, an important gene is the interleukin-1 beta (IL-1β), which has three polymorphisms based on transitions between ... See full document
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Apolipoprotein E polymorphism and the risk of intracranial aneurysms in a Chinese population
... ATTG polymorphism might contribute to the risk of intracranial aneurysms ...candidate genes for intracranial aneurysms ...a Chinese population [23]. Evidence from a meta-analysis of ... See full document
6
Long non-coding RNA H19 and MALAT1 gene variants in patients with ischemic stroke in a northern Chinese Han population
... rs217727 polymorphism was associated with an in- creased risk of ...regression analysis demonstrated that the TT genotype of rs217727 was independently correlated with an increased risk of IS, even after ... See full document
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Original Article Variants in multi-gene polymorphism association analysis of lung cancer in the Chinese Han population
... tion of the short arm of chromosome 3 is one of the most frequent genetic alterations in lung cancers [8-12]. Furthermore, RBMS3 which is located on human short arm of chromosome 3 [13, 14], is a gene that encodes an ... See full document
6
Association of multiple genetic variants with breast cancer susceptibility in the Han Chinese population
... between genes, interactions between genes and the environment, and the effects of LD and the highly variable minor allele frequencies of SNPs in different ...in Chinese people breast cancer cases and ... See full document
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<p><em>SLC30A8, CDKAL1, TCF7L2, KCNQ1</em> and <em>IGF2BP2</em> are Associated with Type 2 Diabetes Mellitus in Iranian Patients</p>
... The FTO rs8050136 polymorphism is associated with high risk of T2D. 17–23 The FTO is a 2-oxoglutarate (2-OG) Fe(II) dependent demethylase. Previous studies demon- strated a potential role of FTO in nucleic acid ... See full document
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In Silico Analysis of the Protein Structure of Tumor Suppressor Genes in Humans
... BRCA2 genes, are the Alpha helix (Hh), Extended Strand (Ee) and Random coil (Cc), with differing number of ...suppressor genes are represented in figure ...Phylogenetic analysis of tumor suppressor ... See full document
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Polymorphisms of VKORC1 and CYP2C9 are associated with warfarin sensitivity in Chinese population
... In Chinese population, both obesity and the genetic polymorphism of genes affecting the warfarin metabolism seem to affect considerably the clinical response to ... See full document
5
Association between COX2 -765G/C polymorphism and periodontitis in Chinese population: a meta-analysis
... Figure 1 illustrates the literature search process in the form of a flow chart. Fifty-five related records were retrieved through database searching. When we first reviewed the titles and abstracts, 47 articles were ... See full document
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Original Article Association of GCKR rs780094 polymorphism with circulating lipid levels in type 2 diabetes and hyperuricemia in Uygur Chinese
... rs780094 polymorphism appeared to show an increased risk of HUA in Uygur male ...the association between rs780094 and lipid profile among T2DM cases, HUA cases and healthy controls in the Uygur ... See full document
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<p>Mutations In Thirty Hotspot Genes In Newly Diagnosed Chinese Multiple Myeloma Patients</p>
... 30 genes) (Figure ...An analysis of associations with survival was performed on genes with a high mutation fre- quency, namely, ATM, CUL4B , and IRF4 ... See full document
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