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Marketed drugs used for the management of hypercholesterolemia as anticancer armament

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Figure

Figure 1 Signaling pathways mechanistically involved in atorvastatin’s ability to inhibit the migratory and invasive potential of different types of cancer cells in vitro.Notes: One of the mechanisms that have been reported in PTeN-positive prostate cancer
Table 1 Selected active or completed clinical trials on simvastatin and atorvastatin for cancer therapeutics and/or cancer prevention
Figure 2 Docking of simvastatin on the human DNA replication licensing factor CDT1.
Figure S1 Proteome profiling indicating alterations in the expression levels of human proteins evoked by the consumption of aspirin alone or combined with caffeine at clinically attainable doses.

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