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The Exonuclease and Host Shutoff Functions of the SOX Protein of Kaposi's Sarcoma-Associated Herpesvirus Are Genetically Separable

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Academic year: 2019

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Figure

FIG. 1. SOX promotes enhanced mRNA turnover. 293T cells weretransfected with either empty vector or a plasmid expressing GFP or
FIG. 3. Analysis of the DNase activity of SOX mutants. LinearizedpCDNA3 plasmid DNA was incubated with aliquots of the indicated
FIG. 5. Distribution of SOX single-function mutations. SOX mu-tations whose proteins lack the shutoff function are indicated with
FIG. 6. SOX promotes degradation of cytoplasmic mRNA. 293T cellswere transfected in duplicate with empty vector or a plasmid expressing

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