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Severe myopathy in mice lacking the MEF2/SRF dependent gene leiomodin 3

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Figure

Figure 1. Lmod3 is expressed selectively in the skeletal muscle and heart.(A) ISH analysis was performed on transverse sections of E10.5 and E12.5
Figure 3. Lmod3-KO mice have a failure-to-thrive phenotype, which is rescued by the MCK-Lmod3 transgene
Figure 4. Loss of LMOD3 causes nemaline myopathy in mice. (A) H&E staining of quadriceps, gastrocnemius, plantaris, and soleus (GPS) muscles from 1-, 3- and 8-week-old WT and KO mice
Figure 5. Regulation of Lmod3 promoter by MEF2 and SRF transcription factors. (A) The
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