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A secreted factor represses cell proliferation in Dictyostelium

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Figure

Fig. 1. (A) The predicted amino acid sequence of AprA. The amino acidsequences from tryptic peptides of AprA are shown by grey boxes
Fig. 4. Disruption of aprA by homologous recombination causescells to form large abnormal structures during development
Fig. 6. The subcellular distribution of AprA. Cells from preparationssimilar to those shown in Fig
Fig. 8. Growing wild-type cells secrete a ~150 kDa factor thatfactor. Conditioned growth media from the indicated cell types werefractionated on the Superose gel filtration column used for Fig
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