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Rapid Microarray Based Detection of Rifampin, Isoniazid, and Fluoroquinolone Resistance in Mycobacterium tuberculosis by Use of a Single Cartridge

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Academic year: 2020

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FIG 1 Principle of isolate detection by the melting curve assay. For the drug resistance-associated targets rpoB RRDR, rpoBcodon 572, katG, gyrA QRDR, and the inhA promoter region, probes representing the wild-type (wt) and mutant (mut)genotypes were spott
FIG 2 Sensitivity of the melting curve assay for the multiplex amplification of the MTBC strain-specificcartridge and the Alere q analyzer
FIG 3 Specificity of the melting curve assay. The x axis shows the mycobacterial species tested, including M
TABLE 1 Discrimination factors determined with array probesa
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