1
Supplementary Data
1
Multiple sequence alignment uploaded as pdf file.
2
Supplementary Material
2
Supplementary Figures and Tables
4
2.1
Supplementary Figures
5
6
7
8
Supplementary Figure 1. Evolutionary divergence analysis of available spike glycoproteins of
9
different strains of SARS-CoV-2; results are represented in a phylogenetic tree.
10
13
Supplementary Figure 2. Ramachandran plot analysis for the tertiary structure of the SARS-CoV-2
14
SGP.
15
Supplementary Material
17
18
Supplementary Figure 3. Population coverage based on MHC restriction data for (A) Central Africa,
19
(B) Central America, (C) East Africa, (D) East Asia - using the Immune Epitope Database analysis
20
Supplementary Figure 4. Population coverage based on MHC restriction data for (E) Europe,
(F)
23
North Africa, (G) North America, (H) Northeast Asia - using the Immune Epitope Database analysis
24
resource.
25
Supplementary Material
27
Supplementary Figure 5. Population coverage based on MHC restriction data for (I)
Oceania, (J)
28
South Africa,
(K) South America,
(L)
South Asia - using the Immune Epitope Database analysis
29
32
33
Supplementary Figure 6. Population coverage based on MHC restriction data for
(M) Southeast Asia,
34
(N) Southwest Asia, (O) West Africa, (P) West Indies - using the Immune Epitope Database analysis
35
Supplementary Material
37
Supplementary Figure 7. 2D representation of the interaction between epitope WTAGAAAYY and
38
HLA-B*15:25 allele.
39
Supplementary Figure 8. 2D representation of the interaction between epitope GAAAYYVGY and
42
HLA-B*15:25 allele.
43
Supplementary Material
45
Supplementary Figure 9. Combined B-cell linear epitope prediction using
(A)
Bepipred linear
46
epitope prediction,
(B)
Chou & Fasman beta-turn prediction,
(C)
Emini surface accessibility
47
Supplementary Figure 10.
Combined B-cell linear epitope prediction using
(D)
Karplus &
51
Schulz flexibility prediction,
(E)
Kolaskar & Tongaonkar antigenicity,
(F)
Parker
52
hydrophilicity prediction methods.
53
Supplementary Material
2.2
Supplementary Tables
55
TABLE S1 Antigenicity prediction of selected epitopes using VaxiJen 2.0 server
56
Epitopes
Antigen Prediction
LTDEMIAQY
Probable NON-ANTIGEN
WTAGAAAYY
Probable ANTIGEN
TSNQVAVLY
Probable ANTIGEN
CVADYSVLY
Probable NON-ANTIGEN
KTSVDCTMY
Probable ANTIGEN
STECSNLLL
Probable ANTIGEN
GAEHVNNSY
Probable ANTIGEN
NIDGYFKIY
Probable NON-ANTIGEN
YSSANNCTF
Probable NON-ANTIGEN
WMESEFRVY
Probable NON-ANTIGEN
SANNCTFEY
Probable NON-ANTIGEN
VASQSIIAY
Probable NON-ANTIGEN
NSFTRGVYY
Probable NON-ANTIGEN
CNDPFLGVY
Probable ANTIGEN
FTNVYADSF
Probable NON-ANTIGEN
GAAAYYVGY
Probable ANTIGEN
RISNCVADY
Probable NON-ANTIGEN
ERDISTEIY
Probable NON-ANTIGEN
ITDAVDCAL
Probable ANTIGEN
RVDFCGKGY
Probable NON-ANTIGEN
NATRFASVY
Probable NON-ANTIGEN
MTSCCSCLK
Probable ANTIGEN
STQDLFLPF
Probable ANTIGEN
57
Epitopes
Alleles
Length
Probability score
GAAAYYVGY
HLA-B*44:03
9
0.7289
HLA-B*53:01
9
0.2176
HLA-B*35:01
9
0.0634
HLA-B*57:01
9
0.0549
HLA-A*02:01
9
0.0005
HLA-B*07:02
9
0.0003
STQDLFLPF
HLA-B*44:03
9
0.8754
HLA-B*53:01
9
0.2737
HLA-B*57:01
9
0.0423
HLA-B*35:01
9
0.0395
HLA-B*07:02
9
0.0122
HLA-A*02:01
9
0.0019
WTAGAAAYY
HLA-B*44:03
9
0.8185
HLA-B*53:01
9
0.5287
HLA-B*57:01
9
0.0527
HLA-B*35:01
9
0.0374
HLA-B*07:02
9
0.0001
HLA-A*02:01
9
0
1 1 0 2 0 3 0 4 0 5 0
X X X X X X
sp|P0DTC2|SPIKE_SARS2_Spike_gl A A DF DEEEF A DEEF A V C N S R G V Y Y D V F R S Q M F . . . F L V L L P L V S S Q V N L T T R T Q L P P A Y T F T P K S V L H S T D
sp|P59594|SPIKE_CVHSA B B KG KdddG B KddG B I C T S R G V Y Y D I F R S Q M F . . F L L . F L T L T S G S D L D R T T F D D V Q A P N Y T Q H S M P E D T L Y L T D
tr|D2E1E7|D2E1E7_CVHSA B B KG KdddG B KddG B I C T S R G V Y Y D I F R S Q M F . . F L L . F L T L T S G S D L D R T T F D D V Q A P N Y T Q H S M P E D T L Y L T D
tr|D2E1D2|D2E1D2_CVHSA B B KG KdddG B KddG B I C T S R G V Y Y D I F R S Q M F . . F L L . F L T L T S G S D L D R T T F D D V Q A P N Y T Q H S M P E D T L Y L T D
tr|A0A166ZL64|A0A166ZL64_9NIDO B B KG KdddG B KddG B I C S S R G V Y Y D I F R S T M F V F L I S Y T T F L I P Y T A T T T . . F S G P T I E N K L N I G S P D N V S V L V G
tr|A0A0U1UYX4|A0A0U1UYX4_CVHSA B B KG KdddG B KddG B I C S S R G V Y Y D I F R S T M F V F L I S Y T T F L I P Y T A T T T . . F K G P T T E N K L N I G S P D N V S V L V G
tr|R9QTA0|R9QTA0_CVHSA B B KG KdddG B KddG B M C S S R G V Y Y D I F R S Q . . I L L . . . L L F L S S A K A Q E G G V I S N K P Q R T F D Q Y T F N D D V L H L T D
tr|A0A0K1Z074|A0A0K1Z074_CVHSA B B KG KdddG B KddG B I C S S R G V Y Y D I F R S Q M K L I F . . . A F L V T L V K A Q E G G V I N L R T Q P K L S Q V S R N D D V L H L T D
sp|Q3LZX1|SPIKE_BCHK3 B B KG KdddG B KddG B I C S S R G V Y Y D I F R S Q M K L I F . . . A F L A N L A K A Q E G G I I S R K P Q P K M A Q V S R N D D V L H L T D
sp|Q3I5J5|SPIKE_BCRP3 B B KG KdddG B KddG B I C S S R G V Y Y D I F R S Q M K L I L . . . A F L A S L A K A Q E G G I I S R K P Q P K M A Q V S R N D N V L H L T D
sp|Q0Q475|SPIKE_BC279 B B KG KdddG B KddG B V C S S R G V Y Y D I F R S Q M K L I F . . . A L L F S L A K A Q E G G I I S R K P Q P K M E K V S R N D D V L H L T D
tr|Q0QDX9|Q0QDX9_CVHSA B B KG KdddG B KddG B V C S S R G V Y Y D I F R S Q M K L I F . . . A L L F S L A K A Q E G G I I S R K P Q P K M E K V S R N D D V L H L T D
tr|A0A2I4AL96|A0A2I4AL96_9TELE B B KG KdddG B KddG B . . . .
tr|A0A1U7RHG6|A0A1U7RHG6_MESAU B B KG KdddG B KddG B . . . .
tr|H0UY28|H0UY28_CAVPO B B KG KdddG B KddG B . . . .
tr|A0A2K5QWK6|A0A2K5QWK6_CEBCA B B KG KdddG B KddG B . . . .
tr|F6UG70|F6UG70_CALJA C C JH JIIIH C JIIH C . . . .
6 0 7 0 8 0 9 0 1 0 0 1 1 0
X X X X X X sp|P0DTC2|SPIKE_SARS2_Spike_gl DF A DEEF A A A DF A DEEF DEEEEEEEEEEEEF A F L F S N V T F F N V L F G V Y F E K S N I I R G W I F G T T S L P F W H A I H V S G T N G T K R D P P N D A S T L D K
sp|P59594|SPIKE_CVHSA KG B KddG B B B KG B KddG KddddddddddddG B F L F S N V T F F N V I F G I Y F E K S N V V R G W V F G S T N L P Y G H T I N H . . . T G P P K D A A T M N K
tr|D2E1E7|D2E1E7_CVHSA KG B KddG B B B KG B KddG KddddddddddddG B F L F S N V T F F N V I F G I Y F E K S N V V R G W V F G S T N L P Y G H T I N H . . . T G P P K D A A T M N K
tr|D2E1D2|D2E1D2_CVHSA KG B KddG B B B KG B KddG KddddddddddddG B F L F S N V T F F N V I F G I Y F E K S N V V R G W V F G S T N L P Y G H T I N H . . . T G P P K D A A T M N K
tr|A0A166ZL64|A0A166ZL64_9NIDO KG B KddG B B B KG B KddG KddddddddddddG B F L F T T L T Y Y S V L F G V Y F D K S N V V R G W I F G T T N R R N W N S W N Q . . . A S P P G H S T I L D T
tr|A0A0U1UYX4|A0A0U1UYX4_CVHSA KG B KddG B B B KG B KddG KddddddddddddG B F L F T T L T Y Y S V L F G V Y F D K S N V V R G W I F G T T N R R N W N S W N Q . . . A S P P G H S T I L D T
tr|R9QTA0|R9QTA0_CVHSA KG B KddG B B B KG B KddG KddddddddddddG B F L F T N V T Y F N V I F G I Y F E R S N V I R G W I F G S T N Y P N R L S L N A A Q . N T I V Y D H P Y D A A T F D R
tr|A0A0K1Z074|A0A0K1Z074_CVHSA KG B KddG B B B KG B KddG KddddddddddddG B F L F S N L T Y F N I L F G I Y F E K S N V I R G W V F G S T N Y P H Q F S L S I Q S . D K I V Y D P K G D A A T F D T
sp|Q3LZX1|SPIKE_BCHK3 KG B KddG B B B KG B KddG KddddddddddddG B F L F S N L T Y F N I L F G V Y F E K S N V I R G W I F G S S N Y P D Q F S L N V D S . D R Y T Y D P D G D A A T F D T
sp|Q3I5J5|SPIKE_BCRP3 KG B KddG B B B KG B KddG KddddddddddddG B F L F S N L T Y F N I L F G V Y F E K S N V I R G W I F G S T N Y P D Q F S L N V D S . D R F T Y D P D G D A A T F D T
sp|Q0Q475|SPIKE_BC279 KG B KddG B B B KG B KddG KddddddddddddG B F L F S N L T Y F N I L F G V Y F E K S N V I R G W I F G S S N Y P D Q F S L N I D S . N K Y T Y D P D G D A A T F D T
tr|Q0QDX9|Q0QDX9_CVHSA KG B KddG B B B KG B KddG KddddddddddddG B F L F S N L T Y F N I L F G V Y F E K S N V I R G W I F G S S N Y P D Q F S L N I D S . N K Y T Y D P D G D A A T F D T
tr|A0A2I4AL96|A0A2I4AL96_9TELE KG B KddG B B B KG B KddG KddddddddddddG B . . . .
tr|A0A1U7RHG6|A0A1U7RHG6_MESAU KG B KddG B B B KG B KddG KddddddddddddG B . . . .
tr|H0UY28|H0UY28_CAVPO KG B KddG B B B KG B KddG KddddddddddddG B . . . .
tr|A0A2K5QWK6|A0A2K5QWK6_CEBCA KG B KddG B B B KG B KddG KddddddddddddG B . . . .
tr|F6UG70|F6UG70_CALJA JH C JIIH C C C JH C JIIH JIIIIIIIIIIIIH C . . . .
1 2 0 1 3 0 1 4 0 1 5 0 1 6 0 1 7 0
X X X X X X sp|P0DTC2|SPIKE_SARS2_Spike_gl DEEEEEEEF A A A DF A A A A DF A DEEF T Q S L L I V N N T V I V C F C P V V Y A N C T F A N V K E Q F N D F L G Y Y H K N N K S W M E S E F R S S N E Y V S Q
sp|P59594|SPIKE_CVHSA KdddddddG B B B KG B B B B KG B KddG S Q S V I I I N N T V I A C F C P V I F A N C T F S N V R N E L D N F F A S K P M G T . . . . Q T H T M D N F E Y I S D
tr|D2E1E7|D2E1E7_CVHSA KdddddddG B B B KG B B B B KG B KddG S Q S V I I I N N T V I A C F C P V I F A N C T F S N V R N E L D N F F A S K P M G T . . . . Q T H T M D N F E Y I S D
tr|D2E1D2|D2E1D2_CVHSA KdddddddG B B B KG B B B B KG B KddG S Q S V I I I N N T V I A C F C P V I F A N C T F S N V R N E L D N F F A S K P M G T . . . . Q T H T M D N F E Y I S D
tr|A0A166ZL64|A0A166ZL64_9NIDO KdddddddG B B B KG B B B B KG B KddG T Q S A L L V N N S I I V C F C P I I Y L N C T Y G A T E Y Q F D N A F I S G . . G A . . . . Q T N T A I N R V D T L R
tr|A0A0U1UYX4|A0A0U1UYX4_CVHSA KdddddddG B B B KG B B B B KG B KddG T Q S A L L V N N S I I V C F C P I I Y L N C T Y G A T E Y Q F D N A F I R D . . G A . . . . Q I N T A I N R V D T L R
tr|R9QTA0|R9QTA0_CVHSA KdddddddG B B B KG B B B B KG B KddG S Q S A I I V N N T I V V C F C P V V Y A N C T Y S H L K N V L T E M F T S R . . N Q . . . . H Y K S W Q H R D V A Y P
tr|A0A0K1Z074|A0A0K1Z074_CVHSA KdddddddG B B B KG B B B B KG B KddG T Q S A I I V N N T I I V C F C P V V Y A N C T Y S H I R Y N L K D M Y T S A . . G T . . . . Q I S S W Q N F D R V E K
sp|Q3LZX1|SPIKE_BCHK3 KdddddddG B B B KG B B B B KG B KddG T Q S A V I V N N T I I V C F C P V V Y A N C T Y S H I R N N L K E M Y T S R . . G T . . . . Q Q N A W Q S F D R V E K
sp|Q3I5J5|SPIKE_BCRP3 KdddddddG B B B KG B B B B KG B KddG T Q S A V I V N N T I I V C F C P V V Y A N C T Y S H I R N N L K E M Y T S R . . G A . . . . Q Q S S W Q S F D R V E K
sp|Q0Q475|SPIKE_BC279 KdddddddG B B B KG B B B B KG B KddG T Q S A I I V N N T I I V C F C P V V Y A N C T Y S H I R N N L K E M Y T S K . . G T . . . . Q Q S S W Q S F D R V E K
tr|Q0QDX9|Q0QDX9_CVHSA KdddddddG B B B KG B B B B KG B KddG T Q S A I I V N N T I I V C F C P V V Y A N C T Y S H I R N N L K E M Y T S K . . G T . . . . Q Q S S W Q S F D R V E K
tr|A0A2I4AL96|A0A2I4AL96_9TELE KdddddddG B B B KG B B B B KG B KddG . . . .
tr|A0A1U7RHG6|A0A1U7RHG6_MESAU KdddddddG B B B KG B B B B KG B KddG . . . .
tr|H0UY28|H0UY28_CAVPO KdddddddG B B B KG B B B B KG B KddG . . . .
tr|A0A2K5QWK6|A0A2K5QWK6_CEBCA KdddddddG B B B KG B B B B KG B KddG . . . .
tr|F6UG70|F6UG70_CALJA JIIIIIIIH C C C JH C C C C JH C JIIH . . . .
1 8 0 1 9 0 2 0 0 2 1 0 2 2 0
X X X X X
sp|P0DTC2|SPIKE_SARS2_Spike_gl A A DEEEEEEF DF DF A A A DF M F L R E F V F K N G Y I Y L P L P L P F L D L E G K . Q G N K N I D F K S K H T P I N V R . . . . D L Q G F S A E V D
sp|P59594|SPIKE_CVHSA B B KddddddG KG KG B B B KG L F L R E F V F K N G F V Y V P L P I A F S D V S E K . S G N K H K D L Y K G Y Q P I D V R . . . . D L S G F N T K F K
tr|D2E1E7|D2E1E7_CVHSA B B KddddddG KG KG B B B KG L F L R E F V F K N G F V Y V P L P I A F S D V S E K . S G N K H K D L Y K G Y Q P I D V R . . . . D L S G F N T K F K
tr|D2E1D2|D2E1D2_CVHSA B B KddddddG KG KG B B B KG L F L R E F V F K N G F V Y V P L P I A F S D V S E K . S G N K H K D L Y K G Y Q P I D V R . . . . D L S G F N T K F K
tr|A0A166ZL64|A0A166ZL64_9NIDO B B KddddddG KG KG B B B KG L F L R E F V F K N G F I Y L P L P L D L P S F E D . V D G G K H S D L H G A Y Q P Y D A I G A T A A L A Q F L P K W K
tr|A0A0U1UYX4|A0A0U1UYX4_CVHSA B B KddddddG KG KG B B B KG L F L R E F V F K N G F I Y L P L P L D L P S F A E . V D G G K H S D L H G A Y Q P Y D A I G A T A A L A Q F L P K W K
tr|R9QTA0|R9QTA0_CVHSA B B KddddddG KG KG B B B KG L F L R E F I F K N G F I Y V P L P V S F Q D V S L K N N V N Q H V D L K S S Y E P I N V S . . . . G I S G F S V K M S
tr|A0A0K1Z074|A0A0K1Z074_CVHSA B B KddddddG KG KG B B B KG L F L R E F V F K N G F V Y L P L P I S F Q D T A P K . S G N I A R D F T Q D Y T P V N L R . . . . G L A G L S V K L K
sp|Q3LZX1|SPIKE_BCHK3 B B KddddddG KG KG B B B KG L F L R E Y V F K N G F V Y L P L P I S F Q D T T P K . T G N K D R D L S Q T Y T A V N P R . . . . G L T G F S V K L K
sp|Q3I5J5|SPIKE_BCRP3 B B KddddddG KG KG B B B KG L F L R E Y V F K N G F V Y L P L P I S F Q D T A P K . T G N K D R D L S Q T Y T A V N P R . . . . G L I G F S V R L K
sp|Q0Q475|SPIKE_BC279 B B KddddddG KG KG B B B KG L F L R E Y V F K N G F V Y L P L P I S F Q D T A P K . T G N K D R D L S Q T Y T A V N P R . . . . G F A G F S V R L K
tr|Q0QDX9|Q0QDX9_CVHSA B B KddddddG KG KG B B B KG L F L R E Y V F K N G F V Y L P L P I S F Q D T A P K . T G N K D K G L R Q T Y T A V N P R . . . . G F A G F S V R L K
tr|A0A2I4AL96|A0A2I4AL96_9TELE B B KddddddG KG KG B B B KG . . . .
tr|A0A1U7RHG6|A0A1U7RHG6_MESAU B B KddddddG KG KG B B B KG . . . .
tr|H0UY28|H0UY28_CAVPO B B KddddddG KG KG B B B KG . . . .
tr|A0A2K5QWK6|A0A2K5QWK6_CEBCA B B KddddddG KG KG B B B KG . . . .
tr|D2E1E7|D2E1E7_CVHSA KG KdddG B B B KdG KG B B KG B KddG KL P G I N I T I A Q A A Y V G L T M L Y N G T I A L N F R A L T F S . . . P A D I W G T S A F Y K P T F K D E T D
tr|D2E1D2|D2E1D2_CVHSA KG KdddG B B B KdG KG B B KG B KddG KL P G I N I T I A Q A A Y V G L T M L Y N G T I A L N F R A L T F S . . . P A D I W G T S A F Y K P T F K D E T D
tr|A0A166ZL64|A0A166ZL64_9NIDO KG KdddG B B B KdG KG B B KG B KddG KL P G L N I T V L Q A A Y V G L T M L F N G T M A L N Y K V T T K P . . . T N . . . . A F Q I N K H T M S N E S N
tr|A0A0U1UYX4|A0A0U1UYX4_CVHSA KG KdddG B B B KdG KG B B KG B KddG KL P G L N I T V L Q A A Y V G L T M L F N G T M A L N Y K V T T K P . . . T N . . . . A F Q I N K H T M S N E S N
tr|R9QTA0|R9QTA0_CVHSA KG KdddG B B B KdG KG B B KG B KddG KL P G I N I T V M Q A A Y V G L T M L F N G T I A L G M R V M T F S . . . N T A N F L T E N Y Y K P R F Q N T V N
tr|A0A0K1Z074|A0A0K1Z074_CVHSA KG KdddG B B B KdG KG B B KG B KddG KL P G I N I T V M T A A Y V G L T M L F N G T I A F S F R V M A F S . . . K T S N Y V P E S Y N K Q S F S N Q T D
sp|Q3LZX1|SPIKE_BCHK3 KG KdddG B B B KdG KG B B KG B KddG KL P G I N I T V M T A A Y V G L T M L F N G T I A F S Y R V M A F S . . . Q T S N F L P E S Y N K Y S F R N E T D
sp|Q3I5J5|SPIKE_BCRP3 KG KdddG B B B KdG KG B B KG B KddG KL P G I N I T V M T A A Y V G L T M L F N G T I A F S Y R V M A F S . . . Q T S N F L P E S Y N K Y T F S N E T N
sp|Q0Q475|SPIKE_BC279 KG KdddG B B B KdG KG B B KG B KddG KL P G I N I T V M N A A Y V G L T M L F N G T I A F S Y R V M T F S . . . Q F S N F L P E S Y N K Y T F S N E T D
tr|Q0QDX9|Q0QDX9_CVHSA KG KdddG B B B KdG KG B B KG B KddG KL P G I N I T V M N A A Y V G L T M L F N G T I A F S Y R V M T F S . . . Q F S N F L P E S Y N K Y T F S N E T D
tr|A0A2I4AL96|A0A2I4AL96_9TELE KG KdddG B B B KdG KG B B KG B KddG K. . . .
tr|A0A1U7RHG6|A0A1U7RHG6_MESAU KG KdddG B B B KdG KG B B KG B KddG K. . . .
tr|H0UY28|H0UY28_CAVPO KG KdddG B B B KdG KG B B KG B KddG K. . . .
tr|A0A2K5QWK6|A0A2K5QWK6_CEBCA KG KdddG B B B KdG KG B B KG B KddG K. . . .
tr|F6UG70|F6UG70_CALJA JH JIIIH C C C JIH JH C C JH C JIIH J. . . .
2 9 0 3 0 0 3 1 0 3 2 0 3 3 0 3 4 0 X X X X X X
sp|P0DTC2|SPIKE_SARS2_Spike_gl EEF DF A DEF DEF A DEEEEEEEEEF A DEEEEEEEF DEF DEEEEEF V D C P L E K C T K S F V K G I Y Q T S N F R V P I V R F P N I T N C P F V F N A T R F A L D S T L T E Q T E S L G E A
sp|P59594|SPIKE_CVHSA ddG KG B KdG KdG B KdddddddddG B KdddddddG KdG KdddddG V D C P L E K C S K S F I K G I Y Q T S N F R V P V V R F P N I T N C P F V F N A T K F S Q N A L V E D V S G D L G E P
tr|D2E1E7|D2E1E7_CVHSA ddG KG B KdG KdG B KdddddddddG B KdddddddG KdG KdddddG V D C P L E K C S K S F I K G I Y Q T S N F R V P V V R F P N I T N C P F V F N A T K F S Q N A L V E D V S G D L G E P
tr|D2E1D2|D2E1D2_CVHSA ddG KG B KdG KdG B KdddddddddG B KdddddddG KdG KdddddG V D C P L E K C S K S F I K G I Y Q T S N F R V P V V R F P N I T N C P F V F N A T K F S Q N A L V E D V S G D L G E P
tr|A0A166ZL64|A0A166ZL64_9NIDO ddG KG B KdG KdG B KdddddddddG B KdddddddG KdG KdddddG I D C P L E K C T K Q F V K G I Y Q T S N F R V P V A R F P N I T N C P F V F N A T R F S Q D A L L D G Q T V D V D K P
tr|A0A0U1UYX4|A0A0U1UYX4_CVHSA ddG KG B KdG KdG B KdddddddddG B KdddddddG KdG KdddddG I D C P L E K C T K Q F V K G I Y Q T S N F R V P V A R F P N I T N C P F V F N A T R F S Q D A L L D G Q T V D V D K P
tr|R9QTA0|R9QTA0_CVHSA ddG KG B KdG KdG B KdddddddddG B KdddddddG KdG KdddddG V D C P L E K C T K N F I K G I Y Q T S N F R V P V V R F P N I T N C P F V F N A T R F S Q D S L L N T S T Q E R D K P
tr|A0A0K1Z074|A0A0K1Z074_CVHSA ddG KG B KdG KdG B KdddddddddG B KdddddddG KdG KdddddG V D C P L E K C T K S F V K G I Y Q T S N F R V P V V R F P N I T N C P F V F N A T R F S Q N A L T N S A V T E L D K P
sp|Q3LZX1|SPIKE_BCHK3 ddG KG B KdG KdG B KdddddddddG B KdddddddG KdG KdddddG V D C P L E K C T K N F V K G I Y Q T S N F R V P V I R F P N I T N C P F V F N A T R F S Q N A L I N D S T Q E R D K P
sp|Q3I5J5|SPIKE_BCRP3 ddG KG B KdG KdG B KdddddddddG B KdddddddG KdG KdddddG I D C P L E K C T K N F V K G I Y Q T S N F R V P V I R F P N I T N C P F V F N A T R F A Q N A L I N S S T Q E R D K P
sp|Q0Q475|SPIKE_BC279 ddG KG B KdG KdG B KdddddddddG B KdddddddG KdG KdddddG V D C P L E K C T K N F V K G I Y Q T S N F R V P V V R F P N I T N C P F V F N A S R F S Q N A L I N S T T Q E R D K P
tr|Q0QDX9|Q0QDX9_CVHSA ddG KG B KdG KdG B KdddddddddG B KdddddddG KdG KdddddG V D C P L E K C T K N F V K G I Y Q T S N F R V P V V R F P N I T N C P F V F N A S R F S Q N A L I N S T T Q E R D K P
tr|A0A2I4AL96|A0A2I4AL96_9TELE ddG KG B KdG KdG B KdddddddddG B KdddddddG KdG KdddddG . . . .
tr|A0A1U7RHG6|A0A1U7RHG6_MESAU ddG KG B KdG KdG B KdddddddddG B KdddddddG KdG KdddddG . . . .
tr|H0UY28|H0UY28_CAVPO ddG KG B KdG KdG B KdddddddddG B KdddddddG KdG KdddddG . . . .
tr|A0A2K5QWK6|A0A2K5QWK6_CEBCA ddG KG B KdG KdG B KdddddddddG B KdddddddG KdG KdddddG . . . .
tr|F6UG70|F6UG70_CALJA IIH JH C JIH JIH C JIIIIIIIIIH C JIIIIIIIH JIH JIIIIIH . . . .
3 5 0 3 6 0 3 7 0 3 8 0 3 9 0 4 0 0 X X X X X X
sp|P0DTC2|SPIKE_SARS2_Spike_gl DEEEF A DEF DEEEEEF DEF DEEF DEEEF DEF DEEEEEEEEEEEEEF DEES V Y A W R R I S C V A D Y S V Y N S F S T F C Y G V S T K L D L C F T N V Y A D S F V I R E V R N K N L A S K P N G D
sp|P59594|SPIKE_CVHSA KdddG B KdG KdddddG KdG KddG KdddG KdG KdddddddddddddG KddS V Y A W R K I S C V A D Y S V Y N S F S T F C Y G V S T K L D L C F S N V Y A D S F V V K D V R E K N L T F K A N G D
tr|D2E1E7|D2E1E7_CVHSA KdddG B KdG KdddddG KdG KddG KdddG KdG KdddddddddddddG KddS V Y A W R K I S C V A D Y S V Y N S F S T F C Y G V S T K L D L C F S N V Y A D S F V V K D V R E K N L T F K A N G D
tr|D2E1D2|D2E1D2_CVHSA KdddG B KdG KdddddG KdG KddG KdddG KdG KdddddddddddddG KddS V Y A W R K I S C V A D Y S V Y N S F S T F C Y G V S T K L D L C F S N V Y A D S F V V K D V R E K N L T F K A N G D
tr|A0A166ZL64|A0A166ZL64_9NIDO KdddG B KdG KdddddG KdG KddG KdddG KdG KdddddddddddddG KddS V Y A W R K I S C V A D Y T V Y N S F S T F C Y G V S S K L D L C F T S V Y A D T F L I R E V R E T D F T S N P I F S
tr|A0A0U1UYX4|A0A0U1UYX4_CVHSA KdddG B KdG KdddddG KdG KddG KdddG KdG KdddddddddddddG KddS V Y A W R K I S C V A D Y T V Y N S F S T F C Y G V S S K L D L C F T S V Y A D T F L I R E V R E T D F T S N P I F S
tr|R9QTA0|R9QTA0_CVHSA KdddG B KdG KdddddG KdG KddG KdddG KdG KdddddddddddddG KddS V Y A W R K I S C V A D Y T V Y N S F S T F C Y G V S S K L D L C F T S V Y A D T F L I R E V R E T D L T S K P I S S
tr|A0A0K1Z074|A0A0K1Z074_CVHSA KdddG B KdG KdddddG KdG KddG KdddG KdG KdddddddddddddG KddS V Y A W R K I S C V A D Y T V Y N S F S T F C Y G V S S K L D L C F T S V Y A D T F L I R E V R E T D F T S N P I F S
sp|Q3LZX1|SPIKE_BCHK3 KdddG B KdG KdddddG KdG KddG KdddG KdG KdddddddddddddG KddN V Y A W R K I S C V A D Y T V Y N S F S T F C Y G V S S K L D L C F T S V Y A D T F L I R E V R E T D L T S K P I S S
sp|Q3I5J5|SPIKE_BCRP3 KdddG B KdG KdddddG KdG KddG KdddG KdG KdddddddddddddG KddN V Y A W R K I S C V A D Y T V Y N S F S T F C Y G V S S K L D L C F T S V Y A D T F L I R E V R E T D L T S K P I S S
sp|Q0Q475|SPIKE_BC279 KdddG B KdG KdddddG KdG KddG KdddG KdG KdddddddddddddG KddN V Y A W R K I S C V A D Y T V Y N S F S T F C Y G V S S K L D L C F T S V Y A D T F L I R E V R E T D L T S K P I S S
tr|Q0QDX9|Q0QDX9_CVHSA KdddG B KdG KdddddG KdG KddG KdddG KdG KdddddddddddddG KddN V Y A W R K I S C V A D Y T V Y N S F S T F C Y G V S S K L D L C F T S V Y A D T F L I R E V R E T D L T S K P I S S
tr|A0A2I4AL96|A0A2I4AL96_9TELE KdddG B KdG KdddddG KdG KddG KdddG KdG KdddddddddddddG Kdd. . . .
tr|A0A1U7RHG6|A0A1U7RHG6_MESAU KdddG B KdG KdddddG KdG KddG KdddG KdG KdddddddddddddG Kdd. . . .
tr|H0UY28|H0UY28_CAVPO KdddG B KdG KdddddG KdG KddG KdddG KdG KdddddddddddddG Kdd. . . .
tr|A0A2K5QWK6|A0A2K5QWK6_CEBCA KdddG B KdG KdddddG KdG KddG KdddG KdG KdddddddddddddG Kdd. . . .
tr|F6UG70|F6UG70_CALJA JIIIH C JIH JIIIIIH JIH JIIH JIIIH JIH JIIIIIIIIIIIIIH JII. . . .
4 1 0 4 2 0 4 3 0 4 4 0 4 5 0 4 6 0 X X X X X X
sp|P0DTC2|SPIKE_SARS2_Spike_gl EEEEF DF DEEEEEEEEEEF DEEEEEEF A DF DF A DEEEEEEEQ I A P G T G I A D Y N Y K L P D D F G C V I A W N S D N Y Y R R L K P F E R D I Q K T N N L S K V G G N Y L L F K S N
sp|P59594|SPIKE_CVHSA ddddG KG KddddddddddG KddddddG B KG KG B KdddddddQ I A P G T G I A D Y N Y K L P D D F G C V L A W N T D N Y Y R R L R P F E R D I Q V M R N I A T S T G N Y K Y L H G K
tr|D2E1E7|D2E1E7_CVHSA ddddG KG KddddddddddG KddddddG B KG KG B KdddddddQ I A P G T G I A D Y N Y K L P D D F G C V L A W N T D N Y Y R R L R P F E R D I Q V M R N I A T S T G N Y K Y L H G K
tr|D2E1D2|D2E1D2_CVHSA ddddG KG KddddddddddG KddddddG B KG KG B KdddddddQ I A P G T G I A D Y N Y K L P D D F G C V L A W N T D N Y Y R R L R P F E R D I Q V M R N I A T S T G N Y K Y L H G K
tr|A0A166ZL64|A0A166ZL64_9NIDO ddddG KG KddddddddddG KddddddG B KG KG B KdddddddQ V A P G T G I A D Y N Y K L P D D F G C V I A W N T D S Y Y R R L K P F E R D L Q V I A K Q V G . . . F S H S S K
tr|A0A0U1UYX4|A0A0U1UYX4_CVHSA ddddG KG KddddddddddG KddddddG B KG KG B KdddddddQ V A P G T G I A D Y N Y K L P D D F G C V I A W N T D S Y Y R R L K P F E R D L Q V I A K Q V G . . . F S H S S K
tr|R9QTA0|R9QTA0_CVHSA ddddG KG KddddddddddG KddddddG B KG KG B KdddddddQ V A P G T G I A D Y N Y K L P D D F G C V I A W N T D Q Y Y R R L K P F E R D L E V T A N Q Q G . . . Y S S K E K
tr|A0A0K1Z074|A0A0K1Z074_CVHSA ddddG KG KddddddddddG KddddddG B KG KG B KdddddddQ V A P G T G I A D Y N Y K L P D D F G C V I A W N T D S Y Y R R L K P F E R D L Q V T A K Y V G . . . F S H S S K
sp|Q3LZX1|SPIKE_BCHK3 ddddG KG KddddddddddG KddddddG B KG KG B KdddddddQ V A P G T G I A D Y N Y K L P D D F G C V I A W N T D N Y Y R R L K P F E R D L E V T A K H T G . . . Y S H K T K
sp|Q3I5J5|SPIKE_BCRP3 ddddG KG KddddddddddG KddddddG B KG KG B KdddddddQ V A P G T G I A D Y N Y K L P D D F G C V I A W N T D Q Y Y R R L K P F E R D L E V T A K Q Q G . . . Y S H K T K
sp|Q0Q475|SPIKE_BC279 ddddG KG KddddddddddG KddddddG B KG KG B KdddddddQ V A P G T G I A D Y N Y K L P D D F G C V I A W N T D Q Y Y R R L K P F E R D L E V T A Q Q Q G . . . Y S Y K E K
tr|Q0QDX9|Q0QDX9_CVHSA ddddG KG KddddddddddG KddddddG B KG KG B KdddddddQ V A P G T G I A D Y N Y K L P D D F G C V I A W N T D Q Y Y R R L K P F E R D L E V T A Q Q Q G . . . Y S Y K E K
tr|A0A2I4AL96|A0A2I4AL96_9TELE ddddG KG KddddddddddG KddddddG B KG KG B Kddddddd. . . .
tr|A0A1U7RHG6|A0A1U7RHG6_MESAU ddddG KG KddddddddddG KddddddG B KG KG B Kddddddd. . . .
tr|H0UY28|H0UY28_CAVPO ddddG KG KddddddddddG KddddddG B KG KG B Kddddddd. . . .
tr|A0A2K5QWK6|A0A2K5QWK6_CEBCA ddddG KG KddddddddddG KddddddG B KG KG B Kddddddd. . . .
4 7 0 4 8 0 4 9 0 5 0 0 5 1 0 5 2 0 X X X X X X
sp|P0DTC2|SPIKE_SARS2_Spike_gl EF A DF A A A DF DF DEEEEEEEEF DEEEEEEEFS T N L Q Y F T G V Y Q R V V V L S F E L L A P A T V C G P K E I Y Q A G S T P C N G V E G F C Y F P S G Q P N G P Y H
sp|P59594|SPIKE_CVHSA dG B KG B B B KG KG KddddddddG KdddddddGS N N L N Y F T G I Y Q R V V V L S F E L L A P A T V C G P K V P F S P D G K P C T P P . A L C Y W P D G Y T T G P Y N
tr|D2E1E7|D2E1E7_CVHSA dG B KG B B B KG KG KddddddddG KdddddddGS N N L N Y F T G I Y Q R V V V L S F E L L A P A T V C G P K V P F S P D G K P C T P P . A L C Y W P D G Y T T G P Y N
tr|D2E1D2|D2E1D2_CVHSA dG B KG B B B KG KG KddddddddG KdddddddGS N N L N Y F T G I Y Q R V V V L S F E L L A P A T V C G P K V P F S P D G K P C T P P . A L C Y W P D G Y T T G P Y N
tr|A0A166ZL64|A0A166ZL64_9NIDO dG B KG B B B KG KG KddddddddG KdddddddGS S N L S Y F N P L Y Q R V V V L S F E L L A P A T V C G P K E . . . E G V L T T D N Q V E A T N
tr|A0A0U1UYX4|A0A0U1UYX4_CVHSA dG B KG B B B KG KG KddddddddG KdddddddGS S N L S Y F N P L Y Q R V V V L S F E L L A P A T V C G P K E . . . E G V L T T D N Q V E A T N
tr|R9QTA0|R9QTA0_CVHSA dG B KG B B B KG KG KddddddddG KdddddddGS S N L S Y F S P L Y Q R V V V L S F E L L A P A T V C G P K D . . . E G V Y T T D Y P V D A T N
tr|A0A0K1Z074|A0A0K1Z074_CVHSA dG B KG B B B KG KG KddddddddG KdddddddGS S N L S Y F N P L Y Q R V V V L S F E L L A P A T V C G P K E . . . E G A R T T D N Q V E A T N
sp|Q3LZX1|SPIKE_BCHK3 dG B KG B B B KG KG KddddddddG KdddddddGS S N L S Y F N P V Y Q R V V V L S F E L L A P A T V C G P K D D . . . G G V Y T T D N P V A A T N
sp|Q3I5J5|SPIKE_BCRP3 dG B KG B B B KG KG KddddddddG KdddddddGS S N L S Y F S P V Y Q R V V V L S F E L L A P A T V C G P K D . . . E G V R T T D Y P V A A T N
sp|Q0Q475|SPIKE_BC279 dG B KG B B B KG KG KddddddddG KdddddddGS S N L S Y F S P V Y Q R V V V L S F E L L A P A T V C G P K D . . . E G V Y T T D Y P I E A T N
tr|Q0QDX9|Q0QDX9_CVHSA dG B KG B B B KG KG KddddddddG KdddddddGS S N L S Y F S P V Y Q R V V V L S F E L L A P A T V C G P K D . . . E G V Y T T D Y P I E A T N
tr|A0A2I4AL96|A0A2I4AL96_9TELE dG B KG B B B KG KG KddddddddG KdddddddG. . . .
tr|A0A1U7RHG6|A0A1U7RHG6_MESAU dG B KG B B B KG KG KddddddddG KdddddddG. . . .
tr|H0UY28|H0UY28_CAVPO dG B KG B B B KG KG KddddddddG KdddddddG. . . .
tr|A0A2K5QWK6|A0A2K5QWK6_CEBCA dG B KG B B B KG KG KddddddddG KdddddddG. . . .
tr|F6UG70|F6UG70_CALJA IH C JH C C C JH JH JIIIIIIIIH JIIIIIIIH. . . .
5 3 0 5 4 0 5 5 0 5 6 0 5 7 0 5 8 0 X X X X X X
sp|P0DTC2|SPIKE_SARS2_Spike_gl DF DEEF DEEEEEEF DEEEEF DEF A DEEEEEF A DF DEEF A DEEEE S T L V K N C V N F N F N G G T G V L T S N K F F Q Q F G R D D T D V R D P T I L D I TK N K L T E K L P I A T A Q L E
sp|P59594|SPIKE_CVHSA KG KddG KddddddG KddddG KdG B KdddddG B KG KddG B Kdddd S T L I K N C V N F N F N G G T G V L T S S K F F Q Q F G R D D T D V R D P T I L D I SL D Q L T P R Q P V S F S K S E
tr|D2E1E7|D2E1E7_CVHSA KG KddG KddddddG KddddG KdG B KdddddG B KG KddG B Kdddd S T L I K N C V N F N F N G G T G V L T S S K F F Q Q F G R D D T D V R D P T I L D I SL D Q L T P R Q P V S F S K S E
tr|D2E1D2|D2E1D2_CVHSA KG KddG KddddddG KddddG KdG B KdddddG B KG KddG B Kdddd S T L I K N C V N F N F N G G T G V L T S S K F F Q Q F G R D D T D V R D P T I L D I SL D Q L T P R Q P V S F S K S E
tr|A0A166ZL64|A0A166ZL64_9NIDO KG KddG KddddddG KddddG KdG B KdddddG B KG KddG B Kdddd S T L V K N C V N F N F N G G T G V L T S S K F F Q Q F G R D D T D V R D P T I L D I SL P Q L K D T Q S A S F S Q L Q
tr|A0A0U1UYX4|A0A0U1UYX4_CVHSA KG KddG KddddddG KddddG KdG B KdddddG B KG KddG B Kdddd S T L V K N C V N F N F N G G T G V L T S S K F F Q Q F G R D D T D V R D P T I L D I SL P Q L K D T Q S A S F S Q L Q
tr|R9QTA0|R9QTA0_CVHSA KG KddG KddddddG KddddG KdG B KdddddG B KG KddG B Kdddd S T L V K N C V N F N F N G G T G V L T S S K F F Q Q F G R D D T D V R D P T I L D I SL T Q L K A K Q S A S F S Q L E
tr|A0A0K1Z074|A0A0K1Z074_CVHSA KG KddG KddddddG KddddG KdG B KdddddG B KG KddG B Kdddd S T L V K N C V N F N F N G G T G V L T S S K F F Q Q F G R D D T D V R D P T I L D I SL S Q F K D T Q S A S F S K L Q
sp|Q3LZX1|SPIKE_BCHK3 KG KddG KddddddG KddddG KdG B KdddddG B KG KddG B Kdddd S T L V K N C V N F N F N G G T G V L T S S K F F Q Q F G R D D T D V R D P T I L D I SL E Q L K S R Q S T S F S Q L E
sp|Q3I5J5|SPIKE_BCRP3 KG KddG KddddddG KddddG KdG B KdddddG B KG KddG B Kdddd S T L V K N C V N F N F N G G T G V L T S S K F F Q Q F G R D D T D V R D P T I L D I SL Q Q L K E R Q S T S F S Q L E
sp|Q0Q475|SPIKE_BC279 KG KddG KddddddG KddddG KdG B KdddddG B KG KddG B Kdddd S T L V K N C V N F N F N G G T G V L T S S K F F Q Q F G R D D T D V R D P T I L D I SL Q Q L R T R Q S T S F S Q L E
tr|Q0QDX9|Q0QDX9_CVHSA KG KddG KddddddG KddddG KdG B KdddddG B KG KddG B Kdddd S T L V K N C V N F N F N G G T G V L T S S K F F Q Q F G R D D T D V R D P T I L D I SL Q Q L R T R Q S T S F S Q L E
tr|A0A2I4AL96|A0A2I4AL96_9TELE KG KddG KddddddG KddddG KdG B KdddddG B KG KddG B Kdddd. . . .
tr|A0A1U7RHG6|A0A1U7RHG6_MESAU KG KddG KddddddG KddddG KdG B KdddddG B KG KddG B Kdddd. . . .
tr|H0UY28|H0UY28_CAVPO KG KddG KddddddG KddddG KdG B KdddddG B KG KddG B Kdddd. . . .
tr|A0A2K5QWK6|A0A2K5QWK6_CEBCA KG KddG KddddddG KddddG KdG B KdddddG B KG KddG B Kdddd. . . .
tr|F6UG70|F6UG70_CALJA JH JIIH JIIIIIIH JIIIIH JIH C JIIIIIH C JH JIIH C JIIII. . . .
5 9 0 6 0 0 6 1 0 6 2 0 6 3 0 6 4 0 X X X X X X
sp|P0DTC2|SPIKE_SARS2_Spike_gl EEEEEEEEEEEEEEF DF DEEEEEEEEEEEF A DF A DEEEEEF DEEF DEP C S F G G V S V I T P G T N S N V A V L Y Q D V N C T E V I A D L W R V Y S T G V F Q T A G T Q P V A H Q T P T S N R
sp|P59594|SPIKE_CVHSA ddddddddddddddG KG KdddddddddddG B KG B KdddddG KddG KdP C S F G G V S V I T P G T N S S V A V L Y Q D V N C T D V I A D L W R I Y S T G V F Q T A G A E S T A H Q T P A N N Q
tr|D2E1E7|D2E1E7_CVHSA ddddddddddddddG KG KdddddddddddG B KG B KdddddG KddG KdP C S F G G V S V I T P G T N S S V A V L Y Q D V N C T D V I A D L W R I Y S T G V F Q T A G A E S T A H Q T P A N N Q
tr|D2E1D2|D2E1D2_CVHSA ddddddddddddddG KG KdddddddddddG B KG B KdddddG KddG KdP C S F G G V S V I T P G T N S S V A V L Y Q D V N C T D V I A D L W R I Y S T G V F Q T A G A E S T A H Q T P A N N Q
tr|A0A166ZL64|A0A166ZL64_9NIDO ddddddddddddddG KG KdddddddddddG B KG B KdddddG KddG KdP C S F G G V S V I T P G T N S S V A V L Y Q D V N C T D V I A D L W R V Y T T G V F Q T A G T A P T T H H T H S P Y Q
tr|A0A0U1UYX4|A0A0U1UYX4_CVHSA ddddddddddddddG KG KdddddddddddG B KG B KdddddG KddG KdP C S F G G V S V I T P G T N S S V A V L Y Q D V N C T D V I A D L W R V Y T T G V F Q T A G T A P T T H H T H S P Y Q
tr|R9QTA0|R9QTA0_CVHSA ddddddddddddddG KG KdddddddddddG B KG B KdddddG KddG KdP C S F G G V S V I T P G T N S T V A V L Y Q D V N C T D V I A D L W R V Y S T G V F Q T A G A E P T A N Q T P A I N Q
tr|A0A0K1Z074|A0A0K1Z074_CVHSA ddddddddddddddG KG KdddddddddddG B KG B KdddddG KddG KdP C S F G G V S V I T P G T N S S V A V L Y Q D V N C T D V I A D L W R V Y T S G V F Q T A G T A P K T H Q A P S P F Q
sp|Q3LZX1|SPIKE_BCHK3 ddddddddddddddG KG KdddddddddddG B KG B KdddddG KddG KdP C S F G G V S V I T P G T N S S V A V L Y Q D V N C T D V I A D L W R V Y S T G V F Q T A G A E P T A R Q T P A V N Q
sp|Q3I5J5|SPIKE_BCRP3 ddddddddddddddG KG KdddddddddddG B KG B KdddddG KddG KdP C S F G G V S V I T P G T N S S V A V L Y Q D V N C T D V I A D L W R V Y S T G V F Q T A G A E P A A H Q T P A T N Q
sp|Q0Q475|SPIKE_BC279 ddddddddddddddG KG KdddddddddddG B KG B KdddddG KddG KdP C S F G G V S V I T P G T N S S V A V L Y Q D V N C T D V I A D L W R V Y S T G V F Q T A G A E P T S H Q T P A V N Q
tr|Q0QDX9|Q0QDX9_CVHSA ddddddddddddddG KG KdddddddddddG B KG B KdddddG KddG KdP C S F G G V S V I T P G T N S S V A V L Y Q D V N C T D V I A D L W R V Y S T G V F Q T A G A E P T S H Q T P A V N Q
tr|A0A2I4AL96|A0A2I4AL96_9TELE ddddddddddddddG KG KdddddddddddG B KG B KdddddG KddG Kd. . . .
tr|A0A1U7RHG6|A0A1U7RHG6_MESAU ddddddddddddddG KG KdddddddddddG B KG B KdddddG KddG Kd. . . .
tr|H0UY28|H0UY28_CAVPO ddddddddddddddG KG KdddddddddddG B KG B KdddddG KddG Kd. . . .
tr|A0A2K5QWK6|A0A2K5QWK6_CEBCA ddddddddddddddG KG KdddddddddddG B KG B KdddddG KddG Kd. . . .
tr|F6UG70|F6UG70_CALJA IIIIIIIIIIIIIIH JH JIIIIIIIIIIIH C JH C JIIIIIH JIIH JI. . . .
6 5 0 6 6 0 6 7 0 6 8 0 6 9 0 7 0 0 X X X X X X
sp|P0DTC2|SPIKE_SARS2_Spike_gl EEEEEEEF DF DEEEEEEEEEEEF A A DEF A DEEEEEEEEEEEEEEEF C L I G A E H V S Y C D I P I G A G I C A S Y T T A R S S S I I A Y T M S L G A E N S V A Y N N E Q Q N S P R R V A Q S
sp|P59594|SPIKE_CVHSA dddddddG KG KdddddddddddG B B KdG B KdddddddddddddddG C L I G A E H V S Y C D I P I G A G I C A S Y T S L R S Q S I V A Y T M S L G A D S S I A Y D T E H V . . . . L T S K S
tr|D2E1E7|D2E1E7_CVHSA dddddddG KG KdddddddddddG B B KdG B KdddddddddddddddG C L I G A E H V S Y C D I P I G A G I C A S Y T S L R S Q S I V A Y T M S L G A D S S I A Y D T E H V . . . . L T S K S
tr|D2E1D2|D2E1D2_CVHSA dddddddG KG KdddddddddddG B B KdG B KdddddddddddddddG C L I G A E H V S Y C D I P I G A G I C A S Y T S L R S Q S I V A Y T M S L G A D S S I A Y D T E H V . . . . L T S K S
tr|A0A166ZL64|A0A166ZL64_9NIDO dddddddG KG KdddddddddddG B B KdG B KdddddddddddddddG C L I G A E H V S Y C D I P I G A G I C A S Y T S L R S Q S I V A Y T M S L G A E N S V A Y N A Q H A . . . . L T G K A
tr|A0A0U1UYX4|A0A0U1UYX4_CVHSA dddddddG KG KdddddddddddG B B KdG B KdddddddddddddddG C L I G A E H V S Y C D I P I G A G I C A S Y T S L R S Q S I V A Y T M S L G A E N S V A Y N A Q H A . . . . L T G K A
tr|R9QTA0|R9QTA0_CVHSA dddddddG KG KdddddddddddG B B KdG B KdddddddddddddddG C L I G A E H V S Y C D I P I G A G I C A S Y T S L R S Q S I V A Y T M S L G A E N S I A Y N A E H A . . . . V T G K A
tr|A0A0K1Z074|A0A0K1Z074_CVHSA dddddddG KG KdddddddddddG B B KdG B KdddddddddddddddG C L I G A E H V S Y C D I P I G A G I C A S Y T S L R S Q S I V A Y T M S L G A E N S V A Y N S E H A . . . . V T G K A
sp|Q3LZX1|SPIKE_BCHK3 dddddddG KG KdddddddddddG B B KdG B KdddddddddddddddG C L I G A E H V S Y C D I P I G A G I C A S Y T S L R S Q S I V A Y T M S L G A E N S I A Y N A E H A . . . . V T G K A
sp|Q3I5J5|SPIKE_BCRP3 dddddddG KG KdddddddddddG B B KdG B KdddddddddddddddG C L I G A E H V S Y C D I P I G A G I C A S Y T S L R S Q S I V A Y T M S L G A E N S I A Y N A E H A . . . . T V G K A
sp|Q0Q475|SPIKE_BC279 dddddddG KG KdddddddddddG B B KdG B KdddddddddddddddG C L I G A E H V S Y C D I P I G A G I C A S Y T S L R S Q S I V A Y T M S L G A E N S I A Y N A E H A . . . . V T G K A
tr|Q0QDX9|Q0QDX9_CVHSA dddddddG KG KdddddddddddG B B KdG B KdddddddddddddddG C L I G A E H V S Y C D I P I G A G I C A S Y T S L R S Q S I V A Y T M S L G A E N S I A Y N A E H A . . . . V T G K A
tr|A0A2I4AL96|A0A2I4AL96_9TELE dddddddG KG KdddddddddddG B B KdG B KdddddddddddddddG . . . .
tr|A0A1U7RHG6|A0A1U7RHG6_MESAU dddddddG KG KdddddddddddG B B KdG B KdddddddddddddddG . . . .
tr|H0UY28|H0UY28_CAVPO dddddddG KG KdddddddddddG B B KdG B KdddddddddddddddG . . . .
tr|A0A2K5QWK6|A0A2K5QWK6_CEBCA dddddddG KG KdddddddddddG B B KdG B KdddddddddddddddG . . . .
tr|D2E1E7|D2E1E7_CVHSA KdddddddddddddddddddddG KG KdddddddddG KG KdddddddddddddddddN N T I A I P T N F S I S I T T E V M P V S M K T V D C N M Y I C G D S E C N L L L Q Y G S F C T Q L N R A L S A S T A
tr|D2E1D2|D2E1D2_CVHSA KdddddddddddddddddddddG KG KdddddddddG KG KdddddddddddddddddN N T I A I P T N F S I S I T T E V M P V S M K T V D C N M Y I C G D S E C N L L L Q Y G S F C T Q L N R A L S A S T A
tr|A0A166ZL64|A0A166ZL64_9NIDO KdddddddddddddddddddddG KG KdddddddddG KG KdddddddddddddddddN N S I A I P T N F S I S V T T E V M P V S M K T V D C T M Y I C G D S E C N L L L Q Y G S F C T Q L N R A L S A S L S
tr|A0A0U1UYX4|A0A0U1UYX4_CVHSA KdddddddddddddddddddddG KG KdddddddddG KG KdddddddddddddddddN N S I A I P T N F S I S V T T E V M P V S M K T V D C T M Y I C G D S E C N L L L Q Y G S F C T Q L N R A L S A S L S
tr|R9QTA0|R9QTA0_CVHSA KdddddddddddddddddddddG KG KdddddddddG KG KdddddddddddddddddN N S I A I P T N F S I S V T T E V M P V S M K T V D C T M Y I C G D S E C N L L L Q Y G S F C T Q L N R A L T A S L S
tr|A0A0K1Z074|A0A0K1Z074_CVHSA KdddddddddddddddddddddG KG KdddddddddG KG KdddddddddddddddddN N S I A I P T N F S I S V T T E V M P V S M K T V D C T M Y I C G D S E C N L L L Q Y G S F C T Q L N R A L S A S A S
sp|Q3LZX1|SPIKE_BCHK3 KdddddddddddddddddddddG KG KdddddddddG KG KdddddddddddddddddN N S I A I P T N F S I S V T T E V M P V S M K T V D C T M Y I C G D S E C N L L L Q Y G S F C T Q L N R A L T A A L S
sp|Q3I5J5|SPIKE_BCRP3 KdddddddddddddddddddddG KG KdddddddddG KG KdddddddddddddddddN N S I A I P T N F S I S V T T E V M P V S M K T V D C T M Y I C G D S E C N L L L Q Y G S F C T Q L N R A L S A S L S
sp|Q0Q475|SPIKE_BC279 KdddddddddddddddddddddG KG KdddddddddG KG KdddddddddddddddddN N S I A I P T N F S I S V T T E V M P V S I K T V D C T M Y I C G D S E C N L L L Q Y G S F C T Q L N R A L T A S L S
tr|Q0QDX9|Q0QDX9_CVHSA KdddddddddddddddddddddG KG KdddddddddG KG KdddddddddddddddddN N S I A I P T N F S I S V T T E V M P V S I K T V D C T M Y I C G D S E C N L L L Q Y G S F C T Q L N R A L T A S L S
tr|A0A2I4AL96|A0A2I4AL96_9TELE KdddddddddddddddddddddG KG KdddddddddG KG Kddddddddddddddddd. . . .
tr|A0A1U7RHG6|A0A1U7RHG6_MESAU KdddddddddddddddddddddG KG KdddddddddG KG Kddddddddddddddddd. . . .
tr|H0UY28|H0UY28_CAVPO KdddddddddddddddddddddG KG KdddddddddG KG Kddddddddddddddddd. . . .
tr|A0A2K5QWK6|A0A2K5QWK6_CEBCA KdddddddddddddddddddddG KG KdddddddddG KG Kddddddddddddddddd. . . .
tr|F6UG70|F6UG70_CALJA JIIIIIIIIIIIIIIIIIIIIIH JH JIIIIIIIIIH JH JIIIIIIIIIIIIIIIII. . . .
7 7 0 7 8 0 7 9 0 8 0 0 8 1 0 8 2 0 X X X X X X
sp|P0DTC2|SPIKE_SARS2_Spike_gl EEEEEEEEEF DEEEEEEEEEEEF DF DEEEEEEEEEEEF DEEEEEEEEEEEEEEEEEG I A V E Q D K N T E V F A Q V K Q I Y K T P I K F G G F N F S Q I L P D P K P S K R S F I E D L L F N K V T L Q P D S
sp|P59594|SPIKE_CVHSA dddddddddG KdddddddddddG KG KdddddddddddG KdddddddddddddddddG I A A E Q D R N T E V F A Q V K Q M Y K T P L K F G G F N F S Q I L P D P K P T K R S F I E D L L F N K V T L R T Y L
tr|D2E1E7|D2E1E7_CVHSA dddddddddG KdddddddddddG KG KdddddddddddG KdddddddddddddddddG I A A E Q D R N T E V F A Q V K Q M Y K T P L K F G G F N F S Q I L P D P K P T K R S F I E D L L F N K V T L R T Y L
tr|D2E1D2|D2E1D2_CVHSA dddddddddG KdddddddddddG KG KdddddddddddG KdddddddddddddddddG I A A E Q D R N T E V F A Q V K Q M Y K T P L K F G G F N F S Q I L P D P K P T K R S F I E D L L F N K V T L R T Y L
tr|A0A166ZL64|A0A166ZL64_9NIDO dddddddddG KdddddddddddG KG KdddddddddddG KdddddddddddddddddG I A V E Q D K N T E V F A Q V K Q M Y K T P I R F G G F N F S Q I L P D P K P T K R S F I E D L L Y N K V T L Q T D L
tr|A0A0U1UYX4|A0A0U1UYX4_CVHSA dddddddddG KdddddddddddG KG KdddddddddddG KdddddddddddddddddG I A V E Q D K N T E V F A Q V K Q M Y K T P I R F G G F N F S Q I L P D P K P T K R S F I E D L L Y N K V T L Q T D L
tr|R9QTA0|R9QTA0_CVHSA dddddddddG KdddddddddddG KG KdddddddddddG KdddddddddddddddddG I A I E Q D K N T E V F A Q V K Q M Y K T P I K F G G F N F S Q I L P D P K P T K R S F I E D L L F N K V T L Q A D S
tr|A0A0K1Z074|A0A0K1Z074_CVHSA dddddddddG KdddddddddddG KG KdddddddddddG KdddddddddddddddddG I A V E Q D K N T E V F A Q V K Q M Y K T P L R F G G F N F S Q I L P D P K P T K R S F I E D L L Y N K V T L Q T D L
sp|Q3LZX1|SPIKE_BCHK3 dddddddddG KdddddddddddG KG KdddddddddddG KdddddddddddddddddG I A I E Q D K N T E V F A Q V K Q M Y K T P I K F G G F N F S Q I L P D P K P T K R S F I E D L L F N K V T L Q A D S
sp|Q3I5J5|SPIKE_BCRP3 dddddddddG KdddddddddddG KG KdddddddddddG KdddddddddddddddddG I A I E Q D K N T E V F A Q V K Q M Y K T P I K F G G F N F S Q I L P D P K P T K R S F I E D L L F N K V T L Q A D S
sp|Q0Q475|SPIKE_BC279 dddddddddG KdddddddddddG KG KdddddddddddG KdddddddddddddddddG I A I E Q D K N T E V F A Q V K Q M Y K T P I K F G G F N F S Q I L P D P K P T K R S F I E D L L F N K V T L Q A D S
tr|Q0QDX9|Q0QDX9_CVHSA dddddddddG KdddddddddddG KG KdddddddddddG KdddddddddddddddddG I A I E Q D K N T E V F A Q V K Q M Y K T P I K F G G F N F S Q I L P D P K P T K R S F I E D L L F N K V T L Q A D S
tr|A0A2I4AL96|A0A2I4AL96_9TELE dddddddddG KdddddddddddG KG KdddddddddddG Kddddddddddddddddd. . . .
tr|A0A1U7RHG6|A0A1U7RHG6_MESAU dddddddddG KdddddddddddG KG KdddddddddddG Kddddddddddddddddd. . . .
tr|H0UY28|H0UY28_CAVPO dddddddddG KdddddddddddG KG KdddddddddddG Kddddddddddddddddd. . . .
tr|A0A2K5QWK6|A0A2K5QWK6_CEBCA dddddddddG KdddddddddddG KG KdddddddddddG Kddddddddddddddddd. . . .
tr|F6UG70|F6UG70_CALJA IIIIIIIIIH JIIIIIIIIIIIH JH JIIIIIIIIIIIH JIIIIIIIIIIIIIIIII. . . .
8 3 0 8 4 0 8 5 0 8 6 0 8 7 0 8 8 0 X X X X X X
sp|P0DTC2|SPIKE_SARS2_Spike_gl EEEEEEEEF DEEF A DEEEEEEEEEEEEEEEEEEEEEEEEF DF DEF DEEF DEEEA D A G F I K Q Y D C L G I A R D L I C A Q K F N G L T V L P P L L T D E M I A Y T A L L G T I T G W T F G D A Q S A S
sp|P59594|SPIKE_CVHSA ddddddddG KddG B KddddddddddddddddddddddddG KG KdG KddG KdddA D A G F M K Q Y E C L G I A R D L I C A Q K F N G L T V L P P L L T D D M I A Y T A L V G T A T G W T F G D N A A S A
tr|D2E1E7|D2E1E7_CVHSA ddddddddG KddG B KddddddddddddddddddddddddG KG KdG KddG KdddA D A G F M K Q Y E C L G I A R D L I C A Q K F N G L T V L P P L L T D D M I A Y T A L V G T A T G W T F G D N A A S A
tr|D2E1D2|D2E1D2_CVHSA ddddddddG KddG B KddddddddddddddddddddddddG KG KdG KddG KdddA D A G F M K Q Y E C L G I A R D L I C A Q K F N G L T V L P P L L T D D M I A Y T A L V G T A T G W T F G D N A A S A
tr|A0A166ZL64|A0A166ZL64_9NIDO ddddddddG KddG B KddddddddddddddddddddddddG KG KdG KddG KdddA D A G F M K Q Y D C L G I A R D L I C A Q K F N G L T V L P P L L T D D M I A Y T A L I G T A T G W T F A G N A A S A
tr|A0A0U1UYX4|A0A0U1UYX4_CVHSA ddddddddG KddG B KddddddddddddddddddddddddG KG KdG KddG KdddA D A G F M K Q Y D C L G I A R D L I C A Q K F N G L T V L P P L L T D D M I A Y T A L I G T A T G W T F A G N A A S A
tr|R9QTA0|R9QTA0_CVHSA ddddddddG KddG B KddddddddddddddddddddddddG KG KdG KddG KdddA D A G F M K Q Y E C L G I A R D L I C A Q K F N G L T V L P P L L T D E M I A Y T A L V G T A T G W T F G D S A A S A
tr|A0A0K1Z074|A0A0K1Z074_CVHSA ddddddddG KddG B KddddddddddddddddddddddddG KG KdG KddG KdddA D A G F M K Q Y D C L G I A R D L I C A Q K F N G L T V L P P L L T D D M I A Y T A L I G T A T G W T F A G N A A S A
sp|Q3LZX1|SPIKE_BCHK3 ddddddddG KddG B KddddddddddddddddddddddddG KG KdG KddG KdddA D A G F M K Q Y D C L G V A R D L I C A Q K F N G L T V L P P L L T D E M V A Y T A L V G T A T G W T F G D S A A S A
sp|Q3I5J5|SPIKE_BCRP3 ddddddddG KddG B KddddddddddddddddddddddddG KG KdG KddG KdddA D A G F M K Q Y E C L G I A R D L I C A Q K F N G L T V L P P L L T D E M I A Y T A L V G T A T G W T F G D S A A S A
sp|Q0Q475|SPIKE_BC279 ddddddddG KddG B KddddddddddddddddddddddddG KG KdG KddG KdddA D A G F M K Q Y E C L G I A R D L I C A Q K F N G L T V L P P L L T D E M I A Y T A L V G T A T G W T F G D S A A S A
tr|Q0QDX9|Q0QDX9_CVHSA ddddddddG KddG B KddddddddddddddddddddddddG KG KdG KddG KdddA D A G F M K Q Y E C L G I A R D L I C A Q K F N G L T V L P P L L T D E M I A Y T A L V G T A T G W T F G D S A A S A
tr|A0A2I4AL96|A0A2I4AL96_9TELE ddddddddG KddG B KddddddddddddddddddddddddG KG KdG KddG Kddd. . . .
tr|A0A1U7RHG6|A0A1U7RHG6_MESAU ddddddddG KddG B KddddddddddddddddddddddddG KG KdG KddG Kddd. . . .
tr|H0UY28|H0UY28_CAVPO ddddddddG KddG B KddddddddddddddddddddddddG KG KdG KddG Kddd. . . .
tr|A0A2K5QWK6|A0A2K5QWK6_CEBCA ddddddddG KddG B KddddddddddddddddddddddddG KG KdG KddG Kddd. . . .
tr|F6UG70|F6UG70_CALJA IIIIIIIIH JIIH C JIIIIIIIIIIIIIIIIIIIIIIIIH JH JIH JIIH JIII. . . .
8 9 0 9 0 0 9 1 0 9 2 0 9 3 0 9 4 0 X X X X X X
sp|P0DTC2|SPIKE_SARS2_Spike_gl EEF DEEEEEEEEEEEEEEEEEEEEEEEEEEEF DEEEEF DF DEEEEEEF DEEEEEG A G A L Q I P F A M Q M A Y R F N G I G V T Q N V L Y E N Q K I A N Q F N A I I Q D S L S S T S A L G K L A L S G K A
sp|P59594|SPIKE_CVHSA ddG KdddddddddddddddddddddddddddG KddddG KG KddddddG KdddddG A G A L Q I P F A M Q M A Y R F N G I G V T Q N V L Y E N Q K I A N Q F N A I I Q E S L T T T T A L G K L A Q K S Q S
tr|D2E1E7|D2E1E7_CVHSA ddG KdddddddddddddddddddddddddddG KddddG KG KddddddG KdddddG A G A L Q I P F A M Q M A Y R F N G I G V T Q N V L Y E N Q K I A N Q F N A I I Q E S L T T T T A L G K L A Q K S Q S
tr|D2E1D2|D2E1D2_CVHSA ddG KdddddddddddddddddddddddddddG KddddG KG KddddddG KdddddG A G A L Q I P F A M Q M A Y R F N G I G V T Q N V L Y E N Q K I A N Q F N A I I Q E S L T T T T A L G K L A Q K S Q S
tr|A0A166ZL64|A0A166ZL64_9NIDO ddG KdddddddddddddddddddddddddddG KddddG KG KddddddG KdddddG A G A L Q I P F A M Q M A Y R F N G I G V T Q N V L Y E N Q K I A N Q F N A I I Q E S L T T T T A L G K L A Q K T Q A
tr|A0A0U1UYX4|A0A0U1UYX4_CVHSA ddG KdddddddddddddddddddddddddddG KddddG KG KddddddG KdddddG A G A L Q I P F A M Q M A Y R F N G I G V T Q N V L Y E N Q K I A N Q F N A I I Q E S L T T T T A L G K L A Q K T Q A
tr|R9QTA0|R9QTA0_CVHSA ddG KdddddddddddddddddddddddddddG KddddG KG KddddddG KdddddG A G A L Q I P F A M Q M A Y R F N G I G V T Q N V L Y E N Q K I A N Q F N A I I Q E S L T T T T A L G K L A Q K S Q S
tr|A0A0K1Z074|A0A0K1Z074_CVHSA ddG KdddddddddddddddddddddddddddG KddddG KG KddddddG KdddddG A G A L Q I P F A M Q M A Y R F N G I G V T Q N V L Y E N Q K I A N Q F N A I I Q E S L T T T T A L G K L A Q K T Q S
sp|Q3LZX1|SPIKE_BCHK3 ddG KdddddddddddddddddddddddddddG KddddG KG KddddddG KdddddG A G A L Q I P F A M Q M A Y R F N G I G V T Q N V L Y E N Q K I A N Q F N A I I Q E S L S S T S A L G K L A L S G K A
sp|Q3I5J5|SPIKE_BCRP3 ddG KdddddddddddddddddddddddddddG KddddG KG KddddddG KdddddG A G A L Q I P F A M Q M A Y R F N G I G V T Q N V L Y E N Q K I A N Q F N A I I Q E S L T T T T A L G K L S Q K S Q S
sp|Q0Q475|SPIKE_BC279 ddG KdddddddddddddddddddddddddddG KddddG KG KddddddG KdddddG A G A L Q I P F A M Q M A Y R F N G I G V T Q N V L Y E N Q K I A N Q F N A I I Q E S L T T T T A L G K L S Q K S Q S
tr|Q0QDX9|Q0QDX9_CVHSA ddG KdddddddddddddddddddddddddddG KddddG KG KddddddG KdddddG A G A L Q I P F A M Q M A Y R F N G I G V T Q N V L Y E N Q K I A N Q F N A I I Q E S L T T T T A L G K L S Q K S Q S
tr|A0A2I4AL96|A0A2I4AL96_9TELE ddG KdddddddddddddddddddddddddddG KddddG KG KddddddG Kddddd. . . .
tr|A0A1U7RHG6|A0A1U7RHG6_MESAU ddG KdddddddddddddddddddddddddddG KddddG KG KddddddG Kddddd. . . .
tr|H0UY28|H0UY28_CAVPO ddG KdddddddddddddddddddddddddddG KddddG KG KddddddG Kddddd. . . .
tr|A0A2K5QWK6|A0A2K5QWK6_CEBCA ddG KdddddddddddddddddddddddddddG KddddG KG KddddddG Kddddd. . . .
9 5 0 9 6 0 9 7 0 9 8 0 9 9 0 1 0 0 0 X X X X X X
sp|P0DTC2|SPIKE_SARS2_Spike_gl EEEEF DEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEQ D V V N N A Q A L N T L V K Q L S S N F G A I S S V L N D I L S R L D K V E A E V Q I D R L I T G R L Q S L Q T Y V Q
sp|P59594|SPIKE_CVHSA ddddG KdddddddddddddddddddddddddddddddddddddddddddddddddddddQ D V V N N A Q A L N T L V K Q L S S N F G A I S S V L N D I L S R L D K V E A E V Q I D R L I T G R L Q S L Q T Y V Q
tr|D2E1E7|D2E1E7_CVHSA ddddG KdddddddddddddddddddddddddddddddddddddddddddddddddddddQ D V V N N A Q A L N T L V K Q L S S N F G A I S S V L N D I L S R L D K V E A E V Q I D R L I T G R L Q S L Q T Y V Q
tr|D2E1D2|D2E1D2_CVHSA ddddG KdddddddddddddddddddddddddddddddddddddddddddddddddddddQ D V V N N A Q A L N T L V K Q L S S N F G A I S S V L N D I L S R L D K V E A E V Q I D R L I T G R L Q S L Q T Y V Q
tr|A0A166ZL64|A0A166ZL64_9NIDO ddddG KdddddddddddddddddddddddddddddddddddddddddddddddddddddQ D V V N N A Q A L N T L V K Q L S S N F G A I S S A L N D I L S R L D K V E A E V Q I D R L I T G R L Q S L Q T Y V Q
tr|A0A0U1UYX4|A0A0U1UYX4_CVHSA ddddG KdddddddddddddddddddddddddddddddddddddddddddddddddddddQ D V V N N A Q A L N T L V K Q L S S N F G A I S S A L N D I L S R L D K V E A E V Q I D R L I T G R L Q S L Q T Y V Q
tr|R9QTA0|R9QTA0_CVHSA ddddG KdddddddddddddddddddddddddddddddddddddddddddddddddddddQ D V V N N A Q A L N T L V K Q L S S N F G A I S S V L N D I L S R L D K V E A E V Q I D R L I T G R L Q S L Q T Y V Q
tr|A0A0K1Z074|A0A0K1Z074_CVHSA ddddG KdddddddddddddddddddddddddddddddddddddddddddddddddddddQ D V V N N A Q A L N T L V K Q L S S N F G A I S S V L N D I L S R L D K V E A E V Q I D R L I T G R L Q S L Q T Y V Q
sp|Q3LZX1|SPIKE_BCHK3 ddddG KdddddddddddddddddddddddddddddddddddddddddddddddddddddQ D V V N N A Q A L N T L V K Q L S S N F G A I S S V L N D I L S R L D K V E A E V Q I D R L I T G R L Q S L Q T Y V Q
sp|Q3I5J5|SPIKE_BCRP3 ddddG KdddddddddddddddddddddddddddddddddddddddddddddddddddddQ D V V N N A Q A L N T L V K Q L S S N F G A I S S V L N D I L S R L D K V E A E V Q I D R L I T G R L Q S L Q T Y V Q
sp|Q0Q475|SPIKE_BC279 ddddG KdddddddddddddddddddddddddddddddddddddddddddddddddddddQ D V V N N A Q A L N T L V K Q L S S N F G A I S S V L N D I L S R L D K V E A E V Q I D R L I T G R L Q S L Q T Y V D
tr|Q0QDX9|Q0QDX9_CVHSA ddddG KdddddddddddddddddddddddddddddddddddddddddddddddddddddQ D V V N N A Q A L N T L V K Q L S S N F G A I S S V L N D I L S R L D K V E A E V Q I D R L I T G R L Q S L Q T Y V Q
tr|A0A2I4AL96|A0A2I4AL96_9TELE ddddG Kddddddddddddddddddddddddddddddddddddddddddddddddddddd. . . .
tr|A0A1U7RHG6|A0A1U7RHG6_MESAU ddddG Kddddddddddddddddddddddddddddddddddddddddddddddddddddd. . . .
tr|H0UY28|H0UY28_CAVPO ddddG Kddddddddddddddddddddddddddddddddddddddddddddddddddddd. . . .
tr|A0A2K5QWK6|A0A2K5QWK6_CEBCA ddddG Kddddddddddddddddddddddddddddddddddddddddddddddddddddd. . . .
tr|F6UG70|F6UG70_CALJA IIIIH JIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIII. . . .
1 0 1 0 1 0 2 0 1 0 3 0 1 0 4 0 1 0 5 0 1 0 6 0 X X X X X X
sp|P0DTC2|SPIKE_SARS2_Spike_gl EEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEF DEEEEEEEEEEEET Q Q L I R A A E I R A S A N L A A T K M S E C V L G Q S K R V D F C G K G Y H L M S F P Q A P H G V V F L H V T Y V S
sp|P59594|SPIKE_CVHSA dddddddddddddddddddddddddddddddddddddddddddddG KddddddddddddT Q Q L I R A A E I R A S A N L A A T K M S E C V L G Q S K R V D F C G K G Y H L M S F P Q A P H G V V F L H V T Y V A
tr|D2E1E7|D2E1E7_CVHSA dddddddddddddddddddddddddddddddddddddddddddddG KddddddddddddT Q Q L I R A A E I R A S A N L A A T K M S E C V L G Q S K R V D F C G K G Y H L M S F P Q A P H G V V F L H V T Y V A
tr|D2E1D2|D2E1D2_CVHSA dddddddddddddddddddddddddddddddddddddddddddddG KddddddddddddT Q Q L I R A A E I R A S A N L A A T K M S E C V L G Q S K R V D F C G K G Y H L M S F P Q A P H G V V F L H V T Y V A
tr|A0A166ZL64|A0A166ZL64_9NIDO dddddddddddddddddddddddddddddddddddddddddddddG KddddddddddddT Q Q L I R A A E I R A S A N L A A T K M S E C V L G Q S K R V D F C G K G Y H L M S F P Q A P H G V V F L H V T Y V S
tr|A0A0U1UYX4|A0A0U1UYX4_CVHSA dddddddddddddddddddddddddddddddddddddddddddddG KddddddddddddT Q Q L I R A A E I R A S A N L A A T K M S E C V L G Q S K R V D F C G K G Y H L M S F P Q A P H G V V F L H V T Y V S
tr|R9QTA0|R9QTA0_CVHSA dddddddddddddddddddddddddddddddddddddddddddddG KddddddddddddT Q Q L I R A A E I R A S A N L A A T K M S E C V L G Q S K R V D F C G K G Y H L M S F P Q A P H G V V F L H V T Y V A
tr|A0A0K1Z074|A0A0K1Z074_CVHSA dddddddddddddddddddddddddddddddddddddddddddddG KddddddddddddT Q Q L I R A A E I R A S A N L A A T K M S E C V L G Q S K R V D F C G K G Y H L M S F P Q A P H G V V F L H V T Y V A
sp|Q3LZX1|SPIKE_BCHK3 dddddddddddddddddddddddddddddddddddddddddddddG KddddddddddddT Q Q L I R A A E I R A S A N L A A T K M S E C V L G Q S K R V D F C G K G Y H L M S F P Q A P H G V V F L H V T Y V S
sp|Q3I5J5|SPIKE_BCRP3 dddddddddddddddddddddddddddddddddddddddddddddG KddddddddddddT Q Q L I R A A E I R A S A N L A A T K M S E C V L G Q S K R V D F C G K G Y H L M S F P Q A P H G V V F L H V T Y V A
sp|Q0Q475|SPIKE_BC279 dddddddddddddddddddddddddddddddddddddddddddddG KddddddddddddT Q Q L I R A A E I R A S A N L A A T K M S E C V L G Q S K R V D F C G K G Y H L M S F P Q A P H G V V F L H V T Y V A
tr|Q0QDX9|Q0QDX9_CVHSA dddddddddddddddddddddddddddddddddddddddddddddG KddddddddddddT Q Q L I R A A E I R A S A N L A A T K M S E C V L G Q S K R V D F C G K G Y H L M S F P Q A P H G V V F L H V T Y V A
tr|A0A2I4AL96|A0A2I4AL96_9TELE dddddddddddddddddddddddddddddddddddddddddddddG Kdddddddddddd. . . .
tr|A0A1U7RHG6|A0A1U7RHG6_MESAU dddddddddddddddddddddddddddddddddddddddddddddG Kdddddddddddd. . . .
tr|H0UY28|H0UY28_CAVPO dddddddddddddddddddddddddddddddddddddddddddddG Kdddddddddddd. . . .
tr|A0A2K5QWK6|A0A2K5QWK6_CEBCA dddddddddddddddddddddddddddddddddddddddddddddG Kdddddddddddd. . . .
tr|F6UG70|F6UG70_CALJA IIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIIH JIIIIIIIIIIII. . . .
1 0 7 0 1 0 8 0 1 0 9 0 1 1 0 0 1 1 1 0 1 1 2 0 X X X X X X
sp|P0DTC2|SPIKE_SARS2_Spike_gl F DEEEEEEEEEEEEEEEF DEEEEEEF DEF DEEEEEEEF DF DEEEEEEF DEF DP Q E K N F T T A P A I C H D G K A F P R E G V F V N G T W F V T Q R N F Y P Q I T T D N T F V G N C V A H S H E I S D
sp|P59594|SPIKE_CVHSA G KdddddddddddddddG KddddddG KdG KdddddddG KG KddddddG KdG KP Q E R N F T T A P A I C H E G K A F P R E G V F V N G T W F I T Q R N F F P Q I T T D N T F V G N C V S Y F S S I S D
tr|D2E1E7|D2E1E7_CVHSA G KdddddddddddddddG KddddddG KdG KdddddddG KG KddddddG KdG KP Q E R N F T T A P A I C H E G K A F P R E G V F V N G T W F I T Q R N F F P Q I T T D N T F V G N C V S Y F S S I S D
tr|D2E1D2|D2E1D2_CVHSA G KdddddddddddddddG KddddddG KdG KdddddddG KG KddddddG KdG KP Q E R N F T T A P A I C H E G K A F P R E G V F V N G T W F I T Q R N F F P Q I T T D N T F V G N C V S Y F S S I S D
tr|A0A166ZL64|A0A166ZL64_9NIDO G KdddddddddddddddG KddddddG KdG KdddddddG KG KddddddG KdG KP Q E K N F T T A P A I C H E G K A F P R E G V F V N G S W F I T Q R N F Y P Q I T T D N T F V G S C V A Y S S S I A D
tr|A0A0U1UY
