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1. Match the trade drugs (column B) with the correct generic drugs (column A). Write the number in column C.

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KEY NAME________________________ QUIZ D

1. Match the trade drugs (column B) with the correct generic drugs (column

A). Write the number in column C.

A B C

1 aminocaproic acid Kabikinase, Streptase 12

2 amlodipine Lopressor 9

3 aspirin Lovenox 6

4 clonidine Norvasc 2

5 dipyridamole Persantine 5

6 enoxaparin Thrombogen, Thrombostat 15

7 heparin Vitamin K, Mephyton 11

8 methyldopa Abbokinase 13

9 metoprolol Adalat, Procardia 10

10 nifedipine Aldomet 8

11 phytonadione Amicar 1

12 streptokinase Bayer, Ecotrin, Ascriptin 3

13 urokinase Catapress, Catapress-TTS 4

14 warfarin Coumadin, Jantoven 14

15 thrombin Hep-Lock 7

Multiple Choice: Circle the ONE best answer to each question.

1. What is the main effect of captopril in the reduction of blood pressure? a. Antagonizes the effects of norepinephrine and epinephrine

b. Prevents the formation of angiotensin by blocking angiotensin-converting enzymes

c. Interferes with the vasomotor center in the brain d. None of the above

2. Warfarin is usually administered: a. IV

b. SC c. PO d. Topically

(2)

3. Which component of plasma in the blood is necessary for clotting? a. Red blood cells

b. White blood cells c. Platelets

d. All of the above

4. Which statement below is true regarding heparin? a. It is the drug of choice for oral anticoagulants

b. It is the drug of choice for pregnant women when an anticoagulant is required c. Hair growth is a secondary side effect to anticoagulation

d. It prevents the synthesis of normal clotting factors

5. Increased hemorrhage may occur when taking aspirin with the following drugs except: a. Enoxaparin

b. Aspirin and dipyridamole c. Warfarin

d. Phytonadione

6. What is the usual dose administration of Vitamin K? a. IV

b. SC c. IM d. Topically

7. The pressure in the arteries when the heart is at rest is called: a. Blood pressure

b. Systolic blood pressure c. Diastolic blood pressure d. Cardiac output

8. A plasma component that protects the body against foreign substances is called: a. Red blood cells

b. White blood cells c. Blue blood cells d. Hemoglobin

9. A blood clot formed by the action of coagulation factors and circulating blood cells is called a/an:

a. Thrombus b. Thrombocyte c. Thrombophlebitis d. Thromboembolism

(3)

10. Drugs that affect the Central Nervous System (CNS) and increase BP include: a. Appetite Suppressants

b. Nasal Decongestants

c. Corticosteroids and NSAID’s d. All of the above

11. The first line drug for treating HTN is/are: a. Vasodilators

b. Diuretics

c. Beta-Adrenergic Blockers d. ACE inhibitors

12. The major type of hypertension in which a cause is unknown is classified as: a. Essential

b. Secondary c. Tertiary d. malignant

13. Factors that affect blood pressure include: a. Cardiac output

b. Increased sympathetic activity c. Peripheral resistance

d. Both A and C e. All of the above

14. Which of the following measurements represents normal blood pressure? a. 90/20

b. 120/80 c. 20/20 d. 210/120

15. How does renal (kidney) disease affect blood pressure?

a. Norepinephrine and epinephrine are secreted which increase heart rate and constrict blood vessels

b. Stimulation of the central nervous system increases heart rate

c. Stimulation of the release of angiotensin and aldosterone increases blood volume d. None of the above

16. Goals of antihypertensive therapy include which of the following: a. Lowering peripheral resistance

b. Producing vasodilation

c. Reducing nervous system stimulation d. All of the above

(4)

17. What is the main effect of beta-blockers in antihypertensive therapy? a. Reduces sodium load and excess blood volume through diuresis b. Direct relaxation of arterial smooth muscles

c. Interferes with the influx of calcium in cardiac and vascular smooth muscles d. Block the release of renin

18. Which of the following statements regarding vasodilators is/are true? a. They are indicated for malignant hypertension

b. They reduce peripheral resistance to lower blood pressure c. Direct relaxation of arterial smooth muscle

d. All of the above are true

19. Contributing lifestyle factors of hypertension include the following except: a. Regular exercise

b. Weight gain

c. Smoking 2 packs of cigarettes each day d. Salty foods

20. Which of the following does not cause secondary hypertension? a. Narrowing of renal arteries

b. The release of norepinephrine and epinephrine c. Taking oral contraceptives

d. Increase blood flow through the kidneys

21. What class of antihypertensive therapy blocks angiotensin-converting enzymes to prevent the formation of angiotensin I to II?

a. Calcium channel blockers b. Sympathetic blocking drugs c. ACE inhibitors

d. Vasodilators

22. What is the main function of fibrinolysin? a. To dissolve blood clots

b. To form a blood clot c. To reduce blood pressure d. To hold platelets in place

23. Enoxaparin (Lovenox®) comes in an oral dosage form: a. True

b. False

24. Loop diuretics such as furosemide (Lasix®), torsemide (Demadex®), and bumetanide (Bumex®) work on the loop of Henle and are the most potent diuretics available:

(5)

25. ARB (angiotensin receptor blockers) such as olmesartan work by preventing the conversion of angiotensin I to angiotensin II by ACE:

a. True b. False

26. Which of the following types of drugs break down blood clots by reversing the clotting order and interfering with the synthesis of clotting factors thus breaking the clot into soluble products?

a. TPA

b. Coumadin® c. Pradaxa® d. Heparin

27. Secondary hypertension affects 90 to 95% of the population: a. True

b. False

28. New guidelines for pre-hypertension that affects 45 million Americans includes people whose blood pressure is ___________________.

a. Diastolic 90-100

b. Systolic 140 and above; Diastolic 90 and above c. Systolic 120-139; Diastolic 80-90

d. Systolic 125-140; Diastolic 85-95

29. All of the following drugs are thrombolytic agents except: a. Streptokinase

b. Urokinase c. Alteplase d. Desirudin

30. __________ consumption can be a serious food-drug interaction with warfarin (Coumadin®) by reducing its effect.

a. Carrots b. Cauliflower c. Spinach d. Apples

31. Emergency heparin-induced bleeding is treated with: a. Vitamin K

b. Phytonadione c. Protamine d. Ice cream

(6)

32. Treatment of overdose for thrombolytic enzymes is: a. Hydrochloric acid

b. Aminocaproic acid c. Protamine zinc d. Vitamin K

33. Aspirin in high doses inhibits platelet aggregation thereby reducing reinfarction and death following a heart attack:

a. True b. False

34. Hypertension diagnosis is positive when diastolic pressure is greater than _____over a chronic period of time:

a. 90 b. 20 c. 150 d. 400

35. Catecholamines such as epinephrine (adrenaline) and norepinephrine (nor-adrenalin) decrease heart rate and dilate blood vessels.

a. True b. False

References

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