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Descriptive statistics; Correlation and regression

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Descriptive statistics; Correlation and regression

Patrick Breheny

September 16

(2)

Tables and figures

Human beings are not good at sifting through large streams of data; we understand data much better when it is

summarized for us

We often display summary statistics in one of two ways:

tables and figures

Tables of summary statistics are very common (we have already seen several in this course) – nearly all published studies in medicine and public health contain a table of basic summary statistics describing their sample

However, figures are usually better than tables in terms of distilling clear trends from large amounts of information

(3)

Types of data

The best way to summarize and present data depends on the type of data

There are two main types of data:

Categorical data: Data that takes on distinct values (i.e., it falls into categories), such as sex (male/female), alive/dead, blood type (A/B/AB/O), stages of cancer

Continuous data: Data that takes on a spectrum of fractional values, such as time, age, temperature, cholesterol levels The distinction between categorical (also called discrete) and continuous data is fundamental and we will return to it

(4)

Categorical data

Summarizing categorical data is pretty straightforward – you just count how many times each category occurs

Instead of counts, we are often interested in percents A percent is a special type of rate, a rate per hundred Counts (also called frequencies), percents, and rates are the three basic summary statistics for categorical data, and are often displayed in tables or bar charts, as we saw in lab

(5)

Continuous data

For continuous data, instead of a finite number of categories, observations can take on a potentially infinite number of values

Summarizing continuous data is therefore much less straightforward

To introduce concepts for describing and summarizing

continuous data, we will look at data on infant mortality rates for 111 nations on three continents: Africa, Asia, and Europe

(6)

Histograms

One very useful way of looking at continuous data is with histograms

To make a histogram, we divide a continuous axis into equally spaced intervals, then count and plot the number of

observations that fall into each interval

This allows us to see how our data points are distributed

(7)

Histogram of European infant mortality rates

Count 46810

Africa

0246810

Asia

0510152025

Europe

(8)

Summarizing continuous data

As we can see, continuous data comes in a variety of shapes Nothing can replace seeing the picture, but if we had to summarize our data using just one or two numbers, how should we go about doing it?

The aspect of the histogram we are usually most interested in is, “Where is its center?”

This is typically represented by the average

(9)

The average and the histogram

The average represents the center of mass of the histogram:

Count 46810

Africa

0246810

Asia

0510152025

Europe

(10)

Spread

The second most important bit of information from the histogram to summarize is, “How spread out are the observations around the center”?

This is most typically represented by the standard deviation To understand how standard deviation works, let’s return to our small example with the numbers {4, 5, 1, 9}

Each of these numbers deviates from the mean by some amount:

4 − 4.75 = −0.75 5 − 4.75 = 0.25 1 − 4.75 = −3.75 9 − 4.75 = 4.25

How should we measure the overall size of these deviations?

(11)

Root-mean-square

Taking their mean isn’t going to tell us anything (why not?) We could take the average of their absolute values:

|−0.75| + |0.25| + |−3.75| + |4.25|

4 = 2.25

But it turns out that for a variety of reasons, the

root-mean-square works better as a measure of overall size:

r(−0.75)2+ (0.25)2+ (−3.75)2+ (4.25)2

4 ≈ 2.86

(12)

The standard deviation

The formula for the standard deviation is

s= s

Pn

i=1(xi− ¯x)2 n −1 Wait a minute; why n −1?

The reason (which we will discuss further in a few weeks) is that dividing by n turns out to underestimate the true standard deviation

Dividing by n −1 instead of n corrects some of that bias The standard deviation of {4, 5, 1, 9} is 3.30 (recall that we got 2.86 if we divide by n)

(13)

Meaning of the standard deviation

The standard deviation (SD) describes how far away numbers in a list are from their average

The SD is often used as a “plus or minus” number, as in

“adult women tend to be about 5’4, plus or minus 3 inches”

Most numbers (roughly 68%) will be within 1 SD away from the average

Very few entries (roughly 5%) will be more than 2 SD away from the average

This rule of thumb works very well for a wide variety of data;

(14)

Standard deviation and the histogram

Background areas within 1 SD of the mean are shaded:

Deaths per 1,000 births Count 0246810

50 100 150 200

Africa

0246

0 50 100 150

Asia

051015

10 20 30 40

Europe

(15)

The 68%/95% rule in action

% of observations within Continent One SD Two SDs

Europe 78 97

Asia 67 97

Africa 63 95

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Summaries can be misleading!

All of the following have the same mean and standard deviation:

−4 −2 0 2 4

Frequency

−4 −2 0 2 4

−4 −2 0 2 4

Frequency

−4 −2 0 2 4

(17)

Percentiles

The average and standard deviation are not the only ways to summarize continuous data

Another type of summary is the percentile

A number is the 25th percentile of a list of numbers if it is bigger than 25% of the numbers in the list

The 50th percentile is given a special name: the median The median, like the mean, can be used to answer the question, “Where is the center of the histogram?”

(18)

Median vs. mean

The dotted line is the median, the solid line is the mean:

Deaths per 1,000 births Count 0246810

50 100 150 200

Africa

0246

0 50 100 150

Asia

051015

10 20 30 40

Europe

(19)

Skew

Note that the histogram for Europe is not symmetric: the tail of the distribution extends further to the right than it does to the left

Such distributions are called skewed

The distribution of infant mortality rates in Europe is said to be right skewed or skewed to the right

For asymmetric/skewed data, the mean and the median will be different

(20)

Hypothetical example

Azerbaijan had the highest infant mortality rate in Europe at 37

What if, instead of 37, it was 200?

Mean Median

Real 14.1 11

Hypothetical 19.2 11 The mean is now higher than 72% of the countries

Note that the average is sensitive to extreme values, while the median is not; statisticians say that the median is robust to the presence of outlying observations

(21)

Box plots

Quantiles are used in a type of graphical summary called a box plot

Box plots are constructed as follows:

Calculate the three quartiles (the 25th, 50th, and 75th) Draw a box bounded by the first and third quartiles and with a line in the middle for the median

Call any observation that is extremely far from the box an

“outlier” and plot the observations using a special symbol (this is somewhat arbitrary and different rules exist for defining outliers)

Draw a line from the top of the box to the highest observation

(22)

Box plots of the infant mortality rate data

Africa Asia Europe

050100150

(23)

Introduction

Box plots are a way to examine the relationship between a continuous variable and a categorical variable

In lab, we saw bar charts as a way of comparing two (or more) categorical variables

Now, we will discuss how to summarize and illustrate the relationship between two continuous variables

(24)

Pearson’s height data

Statisticians in Victorian England were fascinated by the idea of quantifying hereditary influences

Two of the pioneers of modern statistics, the Victorian Englishmen Francis Galton and Karl Pearson were quite passionate about this topic

In pursuit of this goal, they measured the heights of 1,078 fathers and their (fully grown) sons

(25)

The scatter plot

As we’ve mentioned, it is important to plot continuous data – this is especially true when you have two continuous variables and you’re interested in the relationship between them The most common way to plot the relationship between two continuous variables is the two-way scatter plot

Scatter plots are created by setting up two continuous axes, then creating a dot for every pair of observations

(26)

Scatter plot of Pearson’s height data

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60 65 70 75 80

6065707580

Father's height (Inches)

Son's height (Inches)

(27)

Observations about the scatter plot

Taller fathers tend to have taller sons

The scatter plot shows how strong this association is – there is a tendency, but there are plenty of exceptions

(28)

Standardizing a variable

Before we summarize this relationship numerically, we must discuss the idea of standardizing a variable

In Pearson’s height data, one of the sons measured 63.2 inches tall

Because the average height of the sons in the sample was 68.7 inches, another way of describing his height is to say that he was 5.5 inches below average

Furthermore, because the standard deviation of the sons was 2.8 inches, yet another way of describing his height is to say that he was 1.9 standard deviations below the average

(29)

The standardization formula

Putting this into a formula, we standardize an observation xi

by subtracting the average and dividing by the standard deviation:

zi = xi− ¯x SDx

wherex and SD¯ x are the mean and standard deviation of the variable x

One virtue of standardizing a variable is interpretability:

If someone tells you that the concentration of urea in your blood is 50 mg/dL, that likely means nothing to you

(30)

More benefits of standardization

If you standardize all of the observations in your sample, the resulting variable will be “standardized” in the sense of having mean 0 and standard deviation 1

Standardization therefore brings all variables onto a common scale – regardless of whether the heights were originally measured in inches, centimeters, or miles, the standardized heights will be identical

As we will see momentarily, this allows us to study the relationship between two continuous variables without worrying about the scale of measurement

The concept behind standardization – taking an observation, then subtracting the expected value and dividing by the variability – is fundamental to statistics and we will variations on this idea many times in this course

(31)

The correlation coefficient

The summary statistic for describing the strength of

association between two variables is the correlation coefficient, denoted by r (and sometimes called Pearson’s correlation coefficient)

The correlation coefficient is always between 1 (perfect positive correlation) and -1 (perfect negative correlation), and can take on any value in between

A positive correlation means that as one variable increases, the other one tends to increase as well

A negative correlation means that as one variable increases,

(32)

Calculating the correlation coefficient

The correlation coefficient is simply the average of the products of the standardized variables

In mathematical notation, r=

Pn i=1zixzyi n −1 ,

where zix and ziy are the standardized values of x and y Note: The “n versus n −1” issue has nothing to do with correlation; however, if n −1 is used when standardizing, it must be used again here

(33)

Meaning behind the correlation coefficient formula

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Son's height (Inches)

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