1-methyl- 4-phenyl-1
Angiotensin type 1 receptor antagonist losartan, reduces MPTP-induced degeneration of dopaminergic neurons in substantia nigra
... AT 1 receptor, Ang II type 1 receptor; Agtr2, gene encoding AT 2 receptor; BP, blood pressure; CE, coefficient of error; CV, coefficient of vari- ance; DA, dopamine or dopaminergic; DAT, dopamine ...
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Synthesis, characterization and antimicrobial activities of 1 Acetyl 5 (substituted phenyl) {3 [4 (2 methyl 4 benzylidene 5 oxo imidazol 1 yl)]phenyl} 4,5 dihydropyrazol
... ClN 4 O 2 ...ClN 4 O 2 ...N 4 O 4 508.56772 68 183 70.83 70.85 5.51 5.55 11.00 11.02 4 P-4d -2-NO 2 C 28 H 23 N 5 O 4 ...N 4 O 3 ...N 4 O 4 494.54114 72 211 ...
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Ethyl 2 {[(1Z) (3 methyl 5 oxo 1 phenyl 1,5 dihydropyrazol 4 ylidene)(phenyl)methyl]amino} 3 phenylpropanoate
... The title compound, (I), was synthesized by refluxing 1-phenyl-3- methyl-4-benzoyl-5-pyrazolone and ethyl 2-amino-3-phenylpropan- oate in ethanol for about 6 h. The product was recrystallized ...
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Antibacterial activity of 1 (4 methyl sulfonylphenyl) 3 (1 phenyl 3 aryl 1Hpyrazol 4 yl) 2 propen 1 ones and it’s derivatives
... A mixture of 1,3-diphenyl-1H-pyrazole-4-carbaldehyde (2.48gm, 0.01M) and 4-methyl sulfonylphenyl acetophenone (1.98gm, 0.01M) was dissolved in 40ml ethanol. To this mixture, 40% aq. NaOH was added ...
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Crystal structures of (E) (3 ethyl 1 methyl 2,6 diphenylpiperidin 4 ylidene)amino phenyl carbonate and (E) (3 isopropyl 1 methyl 2,6 diphenylpiperidin 4 ylidene)amino phenyl carbonate
... and methyl propyl ketone (1 mol) for (I), and methyl isobutyl ketone (1 mol) for (II), in absolute ...with methyl iodide ...give 1- ...
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N [(3 Methyl 5 oxo 1 phenyl 4,5 dihydro 1H pyrazol 4 ylidene)(phenyl)methyl]glycine ethyl ester
... The title compound was synthesized by re¯uxing a mixture of PMBP (10 mmol) and glycine ethyl ester (10 mmol) in ethane (80 ml) over a steam bath for about 6 h. Excess solvent was removed by evaporation and the solution ...
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4 {[1 (Methoxycarbonyl) 3 (methylsulfanyl)propylamino](phenyl)methylidene}3 methyl 1 phenylpyrazol 5(4H) one
... 1-Phenyl-3-methyl-4-benzoylpyrazolon-5-one (HPMBP), an effective -diketonate, is widely used and well known for its extractive ability. In recent years, it and its metal complexes have also ...
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Crystal structure of (Z) 4 [1 (4 acetylanilino)ethylidene] 3 methyl 1 phenyl 1H pyrazol 5(4H) one
... In the crystal, the molecules are linked by C4—H4 O2 hydrogen bonds (Fig. 2, Table 1). The chains formed by these bonds along the c-axis direction are connected by two weak – stacking interactions [Cg1 ...
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2 Methyl 2 phenyl 1 (pyrrolidin 1 yl)propan 1 one
... Data collection: CAD-4 Software (Enraf–Nonius, 1985); cell refinement: CAD-4 Software; data reduction: XCAD4 (Harms & Wocadlo, 1995); program(s) used to solve structure: SHELXS97 (Sheldrick, 2008); ...
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N′ (2,3 Dimethoxybenzylidene) 5 methyl 1 phenyl 1H pyrazole 4 carbohydrazide
... O1 0.0410 (19) 0.0455 (17) 0.081 (2) 0.0001 (15) −0.0157 (17) −0.0071 (16) O2 0.0498 (19) 0.0475 (17) 0.0510 (18) 0.0034 (15) −0.0022 (16) 0.0070 (14) O3 0.064 (2) 0.0425 (18) 0.073 (2) −0.0084 (16) −0.0122 (18) 0.0007 ...
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2 (5 Methyl 4 phenyl 1,3 thiazol 2 yl) 1 phenylethanol
... Data collection: CAD-4 EXPRESS (Enraf±Nonius, 1994); cell re®nement: CAD-4 EXPRESS (Enraf±Nonius, 1994); data reduction: XCAD4 (Harms & Wocadlo, 1995); program(s) used to solve struc- ture: SHELXS97 ...
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4 Acetyl 5 methyl 1 phenyl 1H pyrazole 3 carboxylic acid
... Data collection: CAD-4 EXPRESS (Enraf±Nonius, 1993); cell re®nement: CAD-4 EXPRESS; data reduction: CAD-4 EXPRESS; program(s) used to solve structure: SHELXS97 (Sheldrick, 1997); program(s) used to ...
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3 Methyl 1 phenyl 4 [(Z) phenyl(p tolylamino)methylene] 1H pyrazol 5(4H) one
... riding model approximation; the methyl groups were rotated for a best fit with the electron density. The N-bound H atom was located in a difference Fourier map and was refined with a distance restraint of N—H = ...
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2 (2 Methyl 6 phenyl 1 propyl 1,4 dihydropyridin 4 ylidene)propanedinitrile
... between the pyridine ring and malonitrile plane (N2 C13 C12 C14 N3 plane) is 5.19 (20)°. The bond distances of C—C bonds in the pyridine ring are considerably shorter than those of normal single bonds (D(C1—C2) = ...
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Crystal structure of 1 methoxy 5 methyl N phenyl 1,2,3 triazole 4 carboxamide
... from the triazole plane by 0.894 (4)A ˚ . The conformation of the CONHR-group is consolodated by an intramolecular N— H N hydrogen bond to an N-atom of the triazole ring, which closes an S(5) ring. In the crystal, ...
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Bis(4 formyl 3 methyl 1 phenyl 1H pyrazol 5 yl) sulfide
... To a 100 ml nitrogen-¯ushed three-neck round-bottomed ¯ask, the catalyst NaH (10 mmol) in DMF was added. Thiourea (10 mmol) in DMF (10 ml) was added dropwise. After 30 min, 5-chloro-3-methyl- ...
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Synthesis, Magnetic, Spectral and Biological Studies of Copper(II) Complexes of 4-Benzoyl-3-Methyl-1-Phenyl-2-Pyrazolin-5-One N(4)-Substituted Thiosemicarbazones
... the 4-benzoyl-3-methyl-1- phenyl-2-pyrazolin-5-one N(4)-substituted thiosemicarbazones and their copper(II) complexes are presents in (Table ...10 4 for the coordinated and ...
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1 (5 Hydroxy 3 methyl 1 phenyl 1H pyrazol 4 yl)ethanone: a new monoclinic polymorph
... 1-Phenyl-3-methyl-5-pyrazolone (7.5 g) was dissolved by heating in tetrahydrofuran (80 ml). Calcium hydroxide (12 g) was added and acetyl chloride (4 ml) was then added dropwise over a period ...
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Crystal structure of 3 methyl 1 phenyl 5 (1H pyrrol 1 yl) 1H pyrazole 4 carbaldehyde
... O1 0.0322 (5) 0.0361 (6) 0.0335 (5) −0.0085 (4) 0.0099 (4) 0.0015 (4) N1 0.0209 (5) 0.0216 (5) 0.0282 (6) 0.0022 (4) 0.0048 (4) −0.0046 (4) N2 0.0209 (5) 0.0177 (5) 0.0251 (5) ...
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Crystal structure of 1 (1 methyl 1H imidazol 2 yl) 4 phenyl 1H 1,2,3 triazole dihydrate
... The thermal cycloaddition of azidoazoles with (trimethylsilyl)ethyne has been reported to require extraordinarily long reaction times and chromatographic separation of the resulting isomers (Zanirato & Cerini, 2005). ...
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