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A REPRODUCTIVE AND DEVELOPMENTAL STUDY FOLLOWING 28 DAYS REPEATED ORAL EXPOSURE OF LEAVES OF PTEROSPERMUM ACERIFOLIUM (L ) WILLD IN WISTAR ALBINO RATS

A REPRODUCTIVE AND DEVELOPMENTAL STUDY FOLLOWING 28 DAYS REPEATED ORAL EXPOSURE OF LEAVES OF PTEROSPERMUM ACERIFOLIUM (L ) WILLD IN WISTAR ALBINO RATS

... Compared with the controls, the 250, 500 and 1000 mg/kg p.o. MEPA did not significantly (p<0.01) alter any of the reproductive parameters investigated, gestation length and neonatal development of pups ...

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Postnatal Developmental Toxicity Of Crocus Sativus (Saffron) In Wistar Rats

Postnatal Developmental Toxicity Of Crocus Sativus (Saffron) In Wistar Rats

... The postnatal developmental toxicity of Crocus sativus (saffron) was evaluated in a mammalian species taking Wistar rat as the model. Saffron administered as an oral gavage from implantation (day 5 post coitus) through ...

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Acute and Sub-Acute Toxicity Profile of the Aqueous Stem Bark Extract of Enantia Chlorantha Oliver (Annonaceae) in Laboratory Animals

Acute and Sub-Acute Toxicity Profile of the Aqueous Stem Bark Extract of Enantia Chlorantha Oliver (Annonaceae) in Laboratory Animals

... Sub-acute toxicity study was carried out following WHO (1992) (27) and OECD 407 (1995) (28) guidelines. Rats deprived of food for 24 hours were divided into four groups of 10 animals each (5 males, and 5 females) ...

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Optimal site selection for a high-resolution ice core record in East Antarctica

Optimal site selection for a high-resolution ice core record in East Antarctica

... > 250 mm years −1 IE accumulation means that, as with much of the East Antarctic coast, there is only a very small band at around 1000 m where both cri- teria are satisfied ...

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Selected aspects of modelling of foreign exchange rates with neural networks

Selected aspects of modelling of foreign exchange rates with neural networks

... Cílem tohoto experimentu je dokázat, zda pro před- povídání budoucího kurzu za 60 min je vhodnější předpovídat hodnotu v čase t + 1 při použití 60min dat nebo zda lze dosáhnout kvalitnější předpovědi v čase t + 4 při ...

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Sub acute and acute toxicity of Ferula asafoetida and Silybum marianum formulation and effect of the formulation on delaying gastric emptying

Sub acute and acute toxicity of Ferula asafoetida and Silybum marianum formulation and effect of the formulation on delaying gastric emptying

... received 250, 500 and 1000 mgkg − 1 asdamarin on daily basis for 28 ...with 1000 mgkg − 1 Asdamarin daily for 28 days, and there was no further treatment for 14 days before the end of ...

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Genotoxicity, acute and subchronic toxicity studies of nano liposomes of Orthosiphon stamineus ethanolic extract in Sprague Dawley rats

Genotoxicity, acute and subchronic toxicity studies of nano liposomes of Orthosiphon stamineus ethanolic extract in Sprague Dawley rats

... and 250 mg/kg/day) with a view to demonstrating any dose related response and no-observed-adverse effects at the lowest dose level ...of 250 mg/kg (group I), 500 mg/kg (group II), or 1000 mg/kg ...

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Fenugreek extract as an inducer of cellular death via autophagy in human T lymphoma Jurkat cells

Fenugreek extract as an inducer of cellular death via autophagy in human T lymphoma Jurkat cells

... with 250, 500 and 1000 μg/mL con- centrations of fenugreek extract for up to 72 hr indi- cated dose and time dependent decrease in viability (Figure ...

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Evaluation of antimicrobial and cytotoxic potential of Argemone mexicana L

Evaluation of antimicrobial and cytotoxic potential of Argemone mexicana L

... from 250-1000 µg/mL, this study aimed to perform a phytochemical screening in order to identify secondary metabolites present in Argemone mexicana L crude ethanolic extract and submit it to a fractionation ...

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Evaluation of Anti-inflammatory Activity of Ethanolic Extract of the Root of Chamaecyparis pisifera (Siebold & Zucc.) Endl.

Evaluation of Anti-inflammatory Activity of Ethanolic Extract of the Root of Chamaecyparis pisifera (Siebold & Zucc.) Endl.

... 2.4 Anti-inflammatory Activity Experimental Procedure Anti-inflammatory activity was assessed by carrageenan induced paw edema method in mice. In this study, mice ICR (Institute of Cancer Research) were taken from ...

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 ANTIOXIDANT POTENTIAL OF VARIOUS EXTRACTS FROM WHOLE PLANTS OF DOLICHOS BIFLORUS (LINN) EVALUATED BY THREE IN VITRO METHODS

 ANTIOXIDANT POTENTIAL OF VARIOUS EXTRACTS FROM WHOLE PLANTS OF DOLICHOS BIFLORUS (LINN) EVALUATED BY THREE IN VITRO METHODS

... Iron is essential for life because it is required for oxygen transport, respiration and activity of many enzymes. However, iron is an extremely reactive metal and catalyzes oxidative changes in lipids, proteins and other ...

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Bioassay of Winter Wheat for Gibberellic Acid Sensitivity

Bioassay of Winter Wheat for Gibberellic Acid Sensitivity

... early even with 1000 ppm (Table 4). This agreed with the test in 2005 when height was measured at 18 DAP, but in 2007, a response was observed for both wheat cul- tivars at 250 ppm when measurements were ...

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Assessment of acute, 14 day, and 13 week repeated oral dose toxicity of Tiglium seed extract in rats

Assessment of acute, 14 day, and 13 week repeated oral dose toxicity of Tiglium seed extract in rats

... Experimental design for single oral dose toxicity study For single oral dose toxicity study, healthy male and fe- male SD rats (7-week old) were randomly assigned to six groups (3/sex/group). Vehicle (1% MC) or graded ...

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Influence of flexibility on the aerodynamic performance of a hovering wing

Influence of flexibility on the aerodynamic performance of a hovering wing

... 75, 250 and ...75, 250 and 1000, the aerodynamic performance that is characterized by the ratio of lift coefficient to drag coefficient is respectively increased by 28%, 23% and 21% when compared ...

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Postnatal developmental toxicity of crocus sativus (saffron) in wistar rats

Postnatal developmental toxicity of crocus sativus (saffron) in wistar rats

... The postnatal developmental toxicity of Crocus sativus (saffron) was evaluated in a mammalian species taking Wistar rat as the model. Saffron administered as an oral gavage from implantation (day 5 post coitus) through ...

5

Pharmacokinetics of surotomycin from phase 1 single and multiple ascending dose studies in healthy volunteers

Pharmacokinetics of surotomycin from phase 1 single and multiple ascending dose studies in healthy volunteers

... mg, 1000 mg, 2000 mg, or 4000 mg) were well tolerated, with all AEs reported as mild to moderate in ...mg, 1000 mg BID) were also well tolerated in healthy adult volun- teers, with all AEs reported as mild ...

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Effect of Flowing Conditions on the Corrosion Inhibition of Carbon Steel by Extract of Buddleia Perfoliata

Effect of Flowing Conditions on the Corrosion Inhibition of Carbon Steel by Extract of Buddleia Perfoliata

... 10 mm long with a diameter of 6 mm were machined and embedded in PTFE exposing an effective surface area of 0.28 cm 2 to the electrolyte. This system was machined to form the rotating disk electrode, which was ground up ...

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Feasibility study of hydropower system in Oman

Feasibility study of hydropower system in Oman

... that 250 to 300 kW of solar panels in the Sultanate are equivalent to the efficiency of (1000) kW in Europe, which encourages the generation of energy using solar energy in a cost-effective manner ...

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ANTIMICROBIAL EFFICACY OF PONGAMIA PINNATA (L) PIERRE AGAINST DENTAL CARIES PATHOGENS OF CLINICAL ORIGIN Sowjanya Pulipati*, P. Srinivasa Babu, R. Sampath, N. Bindu Sree,

ANTIMICROBIAL EFFICACY OF PONGAMIA PINNATA (L) PIERRE AGAINST DENTAL CARIES PATHOGENS OF CLINICAL ORIGIN Sowjanya Pulipati*, P. Srinivasa Babu, R. Sampath, N. Bindu Sree,

... of 250 µg, 500 µg, 750 µg and 1000 µg against dental caries pathogens like Streptococcus mutans, Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, Lactobacillus acidophilus, Pseudomonas ...

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PRECLINICAL ACUTE AND REPEATED DOSE TOXICITY OF PUERARIA TUBEROSA (PTWE) ON CHARLES FOSTER RATS

PRECLINICAL ACUTE AND REPEATED DOSE TOXICITY OF PUERARIA TUBEROSA (PTWE) ON CHARLES FOSTER RATS

... Repeated Dose Toxicity: The repeated dose toxicity study was carried out. Here those animal prepared described above and randomly divided into different group having five animal. Different doses 250, 500, ...

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