4-tetrahydropyrimidine
A GREENER CHEMISTRY APPROACH FOR SYNTHESIS OF 4 (4 HYDROXYPHENYL) 6 METHYL 2 OXO 1,2,3,4 TETRAHYDROPYRIMIDINE 5 CARBOXYLIC ACID ETHYL ESTER
... ABSTRACT: The objective of present research work is to provide green technique for synthesis of 4-(4-Hydroxyphenyl)-6-methyl-2-oxo-1,2,3,4- tetrahydropyrimidine-5-carboxylic acid ethyl ester. ...
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A GREENER CHEMISTRY APPROACH FOR SYNTHESIS OF 4 (4 HYDROXYPHENYL) 6 METHYL 2 OXO 1,2,3,4 TETRAHYDROPYRIMIDINE 5 CARBOXYLIC ACID ETHYL ESTER
... CONCLUSION: In conclusion, microwave technique is advantageous over conventional methods due to shorter reaction times, dry media (thus avoiding the use of harmful solvents), cleaner reactions, easy work up, and ...
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Electrochemical and Thermo Dynamical Investigation of 5-ethyl 4-(4-methoxyphenyl)-6-methyl-2-thioxo-1, 2, 3, 4 tetrahydropyrimidine-5-carboxylate on Corrosion Inhibition Behavior of Aluminium in 1M Hydrochloric Acid Medium
... 5-ethyl 4-(4-methoxyphenyl)-6-methyl-2-thioxo- 1,2,3,4-tetrahydropyrimidine-5-carboxylate (INH) and its corrosion inhibition property on aluminium in 1M HCl using weight loss, potentiodynamic ...
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Synthesis and antimicrobial activity of some ethyl [6 methyl 2 methoxy 3 (substituted phenylethanone) 4 (substituted phenyl)] 1,2,3,4 tetrahydropyrimidine 5 carboxylates
... Fifteen new ethyl 6-methyl-2-methoxy-3-(substituted 1-phenylethanone)-4-(Substituted phenyl)- 1,2,3,4-tetrahydropyrimidine-5-carboxylates (6.a-o) have been synthesized in a two step reaction. In first step ...
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ethyl 4-[3-(4-fluorophenyl)-1-phenyl- 1H-pyrazol-4-yl]-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate 4a and ethyl 4-[3-(4- nitrophenyl)-1-phenyl-1H-pyrazol-4-yl]-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate 4d were found to be the most active compounds in vitro with MIC of 0.02 µg/mL against MTB and were 18 times more potent than isoniazid.
... Ethyl 4-(3- (aryl)-1-phenyl-1 H -pyrazol-4-yl)-6-methyl-2-oxo- 1,2,3,4-tetrahydropyrimidine-5-carboxylate (4a-e) A mixture of 3-aryl-1-phenyl-1 H -pyrazole-4- carbaldehyde ...
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Synthesis and pharmacological screening of novel 6-methyl-2-oxo-4-substituted-5-(5-phenyl-1, 3, 4-oxadiazole-2yl)-1, 2, 3, 4-tetrahydropyrimidine
... (DMSO d6 ): δ 1.07(t, 3H, CH 3 -ester); 2.25 (s, 3H, dihydropyridyl-CH 3 ); 3.93 (q, 2H, CH 2 -ester); 5.15 (d, 1H, dihydropyridyl-CH); 7.2-7.5 (m, 4H, Ar-H) 7.7 (s, 1H, 3-NH); 9.25 (s, 1H, 1-NH), Mass (FAB):237(M+,12%), ...
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Design, synthesis, and characterization of (1-(4-aryl)-1<em>H</em>-1,2,3-triazol-4-yl)methyl, substituted phenyl-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylates against <em>Mycobacterium tuberculosis</em>
... studies, 4-trifluoromethyl aryl azide and prop-2-yn-1-yl 4-(4-fluorophenyl)-6-methyl-2-oxo-1,2,3,4- tetrahydropyrimidine-5-carboxylate were chosen as model substrates (entry 1; compound 7a, ...
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ONE POT SYNTHESIS OF 3, 4 TETRAHYDROPYRIMIDINE 5 CARBOXYLATE USING LANTHANUM (III) CHLORIDE (LACL3 7H2O) AS A CATALYST
... 3, 4- tetrahydropyrimidine-5-carboxylate using Lanthanum (III) chloride heptahydrate, one-step procedure from the Biginelli reaction under reflex condition an excellent yield in a ethanol solvent at ...
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Synthesis, Characterization and Biological activity of Novel 6 Methyl 2 oxo N (4 (Piperidin 1 yl) Phenyl) 1,2,3,4 Tetrahydropyrimidine 5 Carboxamide Derivatives
... available 4-fluoro nitrobenzene and Piperidine in presence of K2CO3 in DMSO solvent lead to compound (b) which was reduced with Raney Ni and hydrazine hydrate to produce amine c, this amine (c) was reacted with ...
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Synthesis, Screening and QSAR Studies of 3-Formyl-2-Thioxo-1,2,3,4-Tetrahydropyrimidine Analogues as Antibacterial Agents
... 5-acyl-6-methyl-4-substituted-2-thioxo-1,2,3,4-tetrahydropyrimidines (1) were synthesized by cyclocondensation reaction between appropriate aldehyde, acetoacetate and thiourea in presence of aluminium chloride and ...
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Spectral Characterization and Vibrational Assignments of Ethyl 4-(3-(2,3-Dihydrobenzofuran-5-Carboxamido)Phenyl)-6-Methyl-2-Oxo-1,2,3,4-Tetrahydropyrimidine-5-Carboxylate by ab Initio Density Functional Method
... C 4 –N 5 , C 1 –N 5 , C 4 –N 7 , C 3 –N 7 , C 27 –N 34 and C 35 –N 34 are calculated about ...–C 4 , C 3 –N 7 –C 4 and C 27 –N 34 –C 35 are ...
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Synthesis and Characterizations of ethyl(2Z)-2-(Aryl)-5-(4-hydroxy-3-methoxyphenyl)-7-methyl-3-oxo-2,3,8,8a-tetrahydro-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate Derivatives as Biological and Antifungal Active Agents
... Medicinal chemistry has several armlets of chemistry and biology. However, incumbent it concerns with the rubric of mechanisms of function and action of drugs. It establishes association between structure and activity in ...
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4 (4 Aminophenylsulfonyl)anilinium toluene 4 sulfonate
... In the structure of the title salt (Fig. 1), the conformation of the dapsone monocation as indicated by the inter-ring dihedral angle [70.19 (17)°], compares with 78.27 (9)° in the 3,5-dinitrosalicylic acid salt (Smith ...
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Branch xylem density variations across the Amazon Basin
... 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 4 3 3 3 3 N-Peru N-Peru N-Peru N-Peru N-Peru N-Peru N-Peru N-Peru N-Peru N-Peru N-Peru N[r] ...
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2 (4 Chlorophenyl) 4 oxo 4 phenylbutanenitrile
... Data collection: CrysAlis PRO Agilent, 2013; cell refinement: CrysAlis PRO; data reduction: CrysAlis PRO; programs used to solve structure: SHELXS2013 Sheldrick, 2008; programs used to r[r] ...
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4 (4 Nitrobenzyl)pyridine
... X-Ray structure of the title compound was never reported before in its non-coordinated form, even though several works have been published on it's pyridiunium salts/adducts. The adducts with carboxilic acids were ...
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4 (4 Heptyloxyphenoxy)phthalonitrile
... 4-Substituted phthalonitriles are generally used for preparing symmetrically and unsymmetrically peripherally substituted phthalocyanine complexes and subphthalocyanines (McKeown, 1998; Leznoff & Lever, ...
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4 (4 Hydroxyphenyldiazenyl)benzonitrile
... A solution of 4-cyanoaniline (0.71 g, 6 mmol) in a solution of hydrochloric acid (6 ml, 4M) was added to a solution of sodium nitrite (0.42 g, 6.1 mmol) in 2 ml water, and the mixture was stirred for 4 h ...
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4 Aminopyridinium 4 aminobenzenesulfonate 4 ammoniobenzenesulfonate monohydrate
... the 4-ammoniobenzenesulfonate zwitterion 4-aminobenzenesulfonate anion are found to be essentially the same and agree with those reported earlier (Rae & Maslen, 1962; Banu & Golzar Hossain, ...the ...
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Vol 4, No 4 (2012)
... In order to test whether the colored species formed in the methods adhere to Beer’s law, absorbances at appropriate lengths of a set of solutions containing varying amounts of OP and specified amounts of reagents(as ...
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