A(H1N1)pdm09
Neuraminidase Gene Variations in Influenza A(H1N1)pdm09 Virus among Patients Admitted to Refferal Pulmonary Hospital, Tehran, Iran in 2009–2013
... Influenza viruses are able to evade immune responses due to constant genetic changes in surface glycoproteins (including NA). Therefore, the antigenic changes of surface glycoproteins are reviewed annually to determine ...
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IgM, IgG, and IgA Antibody Responses to Influenza A(H1N1)pdm09 Hemagglutinin in Infected Persons during the First Wave of the 2009 Pandemic in the United States
... The novel influenza A(H1N1)pdm09 virus caused an influenza pandemic in 2009. IgM, IgG, and IgA antibody responses to A(H1N1)pdm09 hemagglutinin (HA) following A(H1N1)pdm09 virus ...
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Structural Stability of Influenza A(H1N1)pdm09 Virus Hemagglutinins
... seasonal H1N1 virus A/Brisbane/59/2007 (Brisb07) was ...A(H1N1) pdm09 virus A/California/7/2009 (CA709) eluted as a species with a much higher estimated molecular mass of ⬃ 340 ...
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Rapid research response to the 2009 A(H1N1)pdm09 influenza pandemic (Revised)
... NW/TS samples collected from subjects presenting within 2 weeks of onset of illness were tested for A(H1N1)pdm09 influenza virus using a real time, reverse transcriptase polymerase chain reaction (rtRT-PCR) ...
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The hemagglutinin of the influenza A(H1N1)pdm09 is mutating towards stability
... Abstract: The last influenza A pandemic provided an excellent opportunity to study the adaptation of the influenza A(H1N1)pdm09 virus to the human host. Particularly, due to the availability of sequences ...
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Genetic analysis of the complete genome of influenza A (H1N1) pdm09 during the first wave of the pandemic season in Indonesia
... We analyzed the HA receptor-binding site in the influenza A(H1N1)pdm09 viruses, which is crucial for the virus to bind preferentially to the sialic acid receptor on its cell surface in the upper respiratory ...
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Seroprevalence study of infection with influenza A(H1N1)pdm09 virus in San Felipe Town, Chile
... Sample-Size Calculation. A stratified random sam- pling by age groups (0 - 4 years old, 5 - 18 years old and 19+ years old) was carried out, using the consumption of antiviral in the commune as the estimate of prevalence ...
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The spread of influenza A(H1N1)pdm09 in Victorian school children in 2009: implications for revised pandemic planning
... Many countries are now reflecting on their 2009 pandemic experiences and responses to review and revise their pandemic plans. Influenza A(H1N1)pdm09 had a generally mild clinical course resulting in ...
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Molecular diagnosis of microbial copathogens with influenza A(H1N1)pdm09 in Oaxaca, Mexico
... The precise identification of infectious pathogens respon- sible for acute respiratory infections, primarily influenza, is a critical factor for proper treatment of the disease and control during outbreaks and for the ...
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Genetic diversity of HA1 domain of heammaglutinin gene of influenza A(H1N1)pdm09 in Tunisia
... We further compared the amino acid residues consti- tuting the 7 antigenic sites of A/California/07/2009 with those of the Tunisia isolates. Almost all residues were highly conserved in the Tunisian isolates, however ...
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Identification of Amino Acid Substitutions Supporting Antigenic Change of Influenza A(H1N1)pdm09 Viruses
... (41). Surprisingly, we found that most of the substitutions that caused antigenic change in HI assays with ferret and human sera did not result in less efficient virus replication. Substitutions at positions 153 and 156 ...
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Antigenic Drift of the Influenza A(H1N1)pdm09 Virus Neuraminidase Results in Reduced Effectiveness of A/California/7/2009 (H1N1pdm09) Specific Antibodies
... MAb F bound the NA of CA/09 (H1N1)pdm09 and BR/07 (H1N1) in ELISAs but inhibited the activity of previous seasonal virus BR/07 only, and not CA/09, in enzyme- linked lectin assays (ELLAs) (Table 1; ...
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International Laboratory Comparison of Influenza Microneutralization Assays for A(H1N1)pdm09, A(H3N2), and A(H5N1) Influenza Viruses by CONSISE
... H; A(H3N2) virus for laboratory L] (Table 3), the 3-day MN assay showed less variation in titers (i.e., had less discriminating power) (Fig. 2A and C, respectively). Yet there was also variability in the correlations for ...
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Effect of ethnicity on care pathway and outcomes in patients hospitalized with influenza A(H1N1)pdm09 in the UK
... Centers for Disease Control and Prevention (CDC) surveillance data collected during the 2009 pandemic found no ethnic/racial disparities in healthcare-seeking behaviour for in fl uenza-like illness, but higher hospi- ...
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Effect of ethnicity on care pathway and outcomes in patients hospitalized with influenza A(H1N1)pdm09 in the UK
... Centers for Disease Control and Prevention (CDC) surveillance data collected during the 2009 pandemic found no ethnic/racial disparities in healthcare-seeking behaviour for in fl uenza-like illness, but higher hospi- ...
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The Comparative Clinical Course of Pregnant and Non-Pregnant Women Hospitalised with Influenza A(H1N1)pdm09 Infection
... There was no evidence of a greater likelihood of severe outcomes in pregnant women as indicated by length of stay, requirement for Level 2/3 care or mortality. This held true even when adjusted for severity of illness on ...
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Characteristics of oseltamivir resistant influenza A (H1N1) pdm09 virus during the 2013–2014 influenza season in Mainland China
... Oseltamivir was widely used for influenza prevention and treatment in 2009, and has been listed as a stock- piled drug in response to influenza pandemics in many countries after the 2009 pandemic. Emergence of the ...
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Toll-Like Receptor 7 Agonist Imiquimod in Combination with Influenza Vaccine Expedites and Augments Humoral Immune Responses against Influenza A(H1N1)pdm09 Virus Infection in BALB/c Mice
... Toll-like receptors (TLRs) of the innate immune system are known targets for enhancing vaccine efficacy. We investigated whether imiquimod, a synthetic TLR7 agonist, can expedite the immune response against influenza ...
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Epidemiology and clinical manifestations of pandemic a(h1n1)pdm09 in casablanca morocco : may 2009– may 2010
... history of asthma 158 (11.7%), 97 (19.8%) were found to be associated to pandemic influenza infection and hospitalization. Data from international studies reported similar proportions of asthma among hospitalized ...
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The role of pneumonia and secondary bacterial infection in fatal and serious outcomes of pandemic influenza a(H1N1)pdm09
... Sixteen studies reported on influenza A(H1N1)pdm09 cases admitted to ICU wards and are summarised in Table 3. Criteria for admission to ICU varied in the in- cluded studies, including acute respiratory ...
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