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α myosin heavy chain

Specialized mouse embryonic stem cells for studying vascular development

Specialized mouse embryonic stem cells for studying vascular development

... muscle myosin heavy chain with the α-SMA RFP+ smooth muscle ...and α-SMA RFP+ cells during differentiation and that the GFP+ cells colocalize with the vascular-like structures sur- ...

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Myosin heavy chain 2A and α Actin expression in human and murine skeletal muscles at feeding; particularly amino acids

Myosin heavy chain 2A and α Actin expression in human and murine skeletal muscles at feeding; particularly amino acids

... extracellular/intracellular amino acid sensors since muscle cells are sensitive to alterations of amino acid concentrations [49]. Recently, amino acid transporter proteins gained increased interest based on their ability ...

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Robbe_final thesis.docx

Robbe_final thesis.docx

... recombinase drivers, driven by the Nkx2-5 locus, a known cardiac transcription factor expressed only in the developing heart, or a transgene construct containing the cardiac troponin T2 promoter (Tnnt2) driving CRE ...

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Myosin Heavy Chain Expression and Oxidative Modifications in Diabetic Rat Hearts

Myosin Heavy Chain Expression and Oxidative Modifications in Diabetic Rat Hearts

... It is well known that the prime determinant of the con- tractile properties, particularly the maximum shortening velocity, in the muscle cell is the catalytic activity of myofibrillar ATPase (my-ATPase) which resides in ...

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Molecular mechanisms of decreased smooth muscle differentiation marker expression after vascular injury

Molecular mechanisms of decreased smooth muscle differentiation marker expression after vascular injury

... cle α-actin, smooth muscle myosin heavy chain, or a SM22α promoter–β-gal reporter, we collected arteries 7 and 14 days after injury and assessed changes in endogenous protein and mRNA levels ...

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Functional analysis of CASTOR in vertebrate cardiomyocyte differentiation

Functional analysis of CASTOR in vertebrate cardiomyocyte differentiation

... Therefore, two CST mouse strains are presently being constructed. The first strain utilizes the Cre-loxP system such that loxP sites are inserted surrounding an exon common to both CST isoforms to create a null CST ...

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Two peaked increase of serum myosin heavy chain α after triathlon suggests heart muscle cell death

Two peaked increase of serum myosin heavy chain α after triathlon suggests heart muscle cell death

... The study into MHC-α plasma levels after triathlon was designed to address the question of possible cell membrane permeability changes as mechanism for the rise of myocardial biomarkers after endurance exercise. ...

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Molecular cloning and developmental expression patterns of the MyoD and MEF2 families of muscle transcription factors in the carp

Molecular cloning and developmental expression patterns of the MyoD and MEF2 families of muscle transcription factors in the carp

... skeletal myosin heavy chain and α-actin were not detected in northern blot analysis until the heartbeat stage (61 h post-fertilization), which is consistent with their expression being a ...

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Temperature and the expression of seven muscle specific protein genes
during embryogenesis in the Atlantic cod Gadus morhua L

Temperature and the expression of seven muscle specific protein genes during embryogenesis in the Atlantic cod Gadus morhua L

... included α- actin, which forms the backbone of the thin filament in the myofibril (Gordon et ...2000); myosin heavy chain (MyHC), which is the major component of the thick filament and the ...

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The omega-3 fatty acid, eicosapentaenoic acid (EPA), prevents the damaging effects of tumour necrosis factor (TNF)-alpha during murine skeletal muscle cell differentiation

The omega-3 fatty acid, eicosapentaenoic acid (EPA), prevents the damaging effects of tumour necrosis factor (TNF)-alpha during murine skeletal muscle cell differentiation

... inhibits myosin heavy chain (MyHC) expression and myogenic differentiation [13-16] whereas treatment of differenti- ated myotubes with TNF-α appears to have marginal effects on their total or ...

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Neonatal cardiomyopathy in mice homozygous for the Arg403Gln mutation in the α cardiac myosin heavy chain gene

Neonatal cardiomyopathy in mice homozygous for the Arg403Gln mutation in the α cardiac myosin heavy chain gene

... Familial hypertrophic cardiomyopathy (FHC) is inherit- ed as an autosomal dominant trait that is character- ized by unexplained hypertrophy of the ventricular myocardium with histologic evidence of myocyte and ...

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Masticatory (`superfast') myosin heavy chain and embryonic/atrial myosin light chain 1 in rodent jaw closing muscles

Masticatory (`superfast') myosin heavy chain and embryonic/atrial myosin light chain 1 in rodent jaw closing muscles

... (MHC- α ). An immunoblot with an anti-MHC- α antibody revealed that the slower migrating cardiac MHC isoform (the predominant isoform in the gray squirrel left atrium) was, in fact, MHC- α ...

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Agaro Oligosaccharides Prevent Myostatin Hyperexpression and Myosin Heavy Chain Protein Degradation in C2C12 Myotubes Induced by Tumor Necrosis Factor α

Agaro Oligosaccharides Prevent Myostatin Hyperexpression and Myosin Heavy Chain Protein Degradation in C2C12 Myotubes Induced by Tumor Necrosis Factor α

... myogenin, myosin light chain 3f (Mlc3f), myostatin, la- tent transforming growth factor beta binding protein 3 (Ltbp3), growth and dif- ferentiation factor-associated serum protein 1 (Gasp1), and Hprt1 were ...

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Original Article All-trans retinoic acid in combination with collagen IV induces the differentiation of mouse embryonic stem cells into smooth muscle cells

Original Article All-trans retinoic acid in combination with collagen IV induces the differentiation of mouse embryonic stem cells into smooth muscle cells

... detect α-smooth muscle actin (α-SMA) and smooth muscle myosin heavy chain (SM-MHC) expression in differentiation of ...of α-SMA and SM-MHC in differentiation of ESC at 7 and 14 ...

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Myosin heavy chain gene expression in human heart failure

Myosin heavy chain gene expression in human heart failure

... of myosin heavy chain (MyHC), a and b , ex- ist in the mammalian ventricular myocardium, and their relative expression is correlated with the contractile velocity of cardiac ...

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Congenital myopathies: clinical phenotypes and new diagnostic tools

Congenital myopathies: clinical phenotypes and new diagnostic tools

... termed myosin storage myopathy [35], is a rare condi- tion associated with mutations in a myosin heavy chain beta (MHC-β) isoform that is expressed primarily in the heart, but also in type 1 ...

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The myosin light chain 1 isoform associated with masticatory myosin heavy chain in mammals and reptiles is embryonic/atrial MLC1

The myosin light chain 1 isoform associated with masticatory myosin heavy chain in mammals and reptiles is embryonic/atrial MLC1

... All of the methods for sample preparation, gel electrophoresis for examination of MHC and MLC isoforms, dot blots, extraction of myosin from single muscle fibers for identification of MLC isoforms, and mass ...

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GAP45 Phosphorylation Controls Assembly of the Toxoplasma Myosin XIV Complex

GAP45 Phosphorylation Controls Assembly of the Toxoplasma Myosin XIV Complex

... the myosin XIV motor complex of Toxo- plasma gondii consists of four proteins, namely, the myosin XIV heavy chain (MyoA), MLC1, the membrane anchor GAP50, and GAP45 ...the myosin XIV ...

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Androgen receptor is expressed in mouse cardiomyocytes at prenatal and early postnatal developmental stages

Androgen receptor is expressed in mouse cardiomyocytes at prenatal and early postnatal developmental stages

... beta myosin heavy chain genes (Myh6 and Myh7) and atrial natriuretic peptide gene (Nppa) at prenatal and early postnatal stages of mouse heart develop- ...

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Myosin heavy chain and physiological adaptation of the rat diaphragm in elastase-induced emphysema

Myosin heavy chain and physiological adaptation of the rat diaphragm in elastase-induced emphysema

... In humans, our group and one other have demonstrated marked alterations in MHC expression in the diaphragm in severe emphysema [12,13]. This shift toward slow MHC isoforms has been proposed to subserve an adaptive ...

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