AAA-ATPase
Maintenance of Nucleosomal Balance in cis by Conserved AAA-ATPase Yta7
... putative AAA-ATPase domain is of the NSF/Cdc48/Pex family, which typically form hexame- ric complexes and participate in unfolding or manipulating proteins (Erzberger and Berger ...its ATPase ...
23
Heubes, Simone (2007): The AAA-ATPase p97 in mitosis and fertilization. Dissertation, LMU München: Fakultät für Biologie
... (Desai and Mitchison, 1997). While interphase MT arrays are relatively stable, mitotic MTs switch very frequently between growth and shrinkage. Upon entry into mitosis, MTs emanating from centrosomes are thus enabled to ...
108
Bussemer, Johanna (2009): Identifizierung und Charakterisierung von AFG1L1 einer dual-lokalisierten, Calmodulin-bindenden AAA+-ATPase aus A. thaliana. Dissertation, LMU München: Fakultät für Biologie
... Chloroplasten entstanden in eukaryotischen Zellen, die schon ein System für die Translokation mitochondrialer Vorstufenproteine besaßen. Deshalb musste sich ein unabhängiges System für den Import chloroplastidärer ...
109
AAA-ATPase p97 suppresses apoptotic and autophagy-associated cell death in rheumatoid arthritis synovial fibroblasts
... The expression of p97 and the expression of HDAC6 in RASFs and OASFs Since both p97 and HDAC6 control the fate of misfolded proteins [9], we first evaluated the expression levels of p97 [r] ...
12
DNAAF1 links heart laterality with the AAA+ ATPase RUVBL1 and ciliary intraflagellar transport
... However, RUVBL1 evidently has other direct or indirect roles in these processes because we unexpectedly observed asymmetric left-handed distribution of RUVBL1 both at the embryonic node [r] ...
17
Schuberth, Christian (2006): UBX-Domänen-Proteine als neue Familie von Kofaktoren der AAA-ATPase Cdc48. Dissertation, LMU München: Fakultät für Biologie
... denen AAA-Proteine wirken, lassen sich einige Gemeinsamkeiten bei der Funktionsweise ...feststellen. AAA-ATPasen bilden Oligomere - meist Hexamere -, die im Falle der TypII-ATPasen (zwei D-Domänen) stabile ...
105
Search | Preprints
... the AAA-ATPase family and, in concert with various chaperones, are responsible for the ATP dependent extraction of ubiquitinated proteins from membranes or aggregates, followed by entrance into the ...
22
SPATA5 mutations cause a distinct autosomal recessive phenotype of intellectual disability, hypotonia and hearing loss
... Fig. 3 Structure of the AAA ATPase domains of SPATA5. a Model of the hexameric quaternary structure of SPATA5 showing the individual subunits in different colours. ADP-molecules bound to the ATPase ...
7
From neurodevelopment to neurodegeneration: the interaction of neurofibromin and valosin-containing protein/p97 in regulation of dendritic spine formation
... AAA ATPase: ATPases Associated with a variety of cellular Activities APTase; ALS: amyotrophic lateral sclerosis; CRMP: collapsing response mediator protein; CTD: C-terminal domain; Ena/V[r] ...
7
The cytosolic fate of ricin A chain in target cells
... RABINOVICH E., KEREM A., FRÖHLICH K.U., DIAMANT N., BAR-NUN S., 2002, AAA-ATPase p97/Cdc48, a cytosolic chaperone required for endoplasmic reticulum-associated protein degradation, Molec[r] ...
299
Unscrambling an egg: protein disaggregation by AAA+ proteins
... The second model relies on the observation that coopera- tion of the two chaperone systems exists only between proteins of the same species [40,49]. Thus, mixtures of S. cerevisiae Hsp104 and E. coli DnaK (and vice ...
12
Ouabain insensitive K adenosine triphosphatase in distal nephron segments of the rabbit
... vanadate but also by omeprazole and SCH 28080 (relatively specific inhibitors of gastric H- K-ATPase). It is concluded that K-ATPase present in the CNT, CCD, and MCD has some properties in common with ...
6
Molecular cloning and characterization of a Ca2+ + Mg2+ dependent adenosine triphosphatase from rat cardiac sarcoplasmic reticulum Regulation of its expression by pressure overload and developmental stage
... nucleotides and deduced amino acid sequences of pHA6 showed striking homology, 89 and 98%, respectively, to those of rabbit Ca2+-ATPase of the slow-twitch form. Northern blot analyses revealed that the mRNA levels ...
8
Seawater acclimation causes independent alterations in Na+/K+ and H+ ATPase activity in isolated mitochondria rich cell subtypes of the rainbow trout gill
... gills of seawater-acclimated trout compared with that observed in the freshwater fish gill. This increase is in agreement with previously published figures (Epstein et al., 1980; Kultz et al., 1992; Wilson et al., 2002). ...
8
Immunochemical analysis of the vacuolar proton ATPase B subunit in the gills of a euryhaline stingray (Dasyatis sabina): effects of salinity and relation to Na+/K+ ATPase
... Potamotrygonid stingrays of the Amazon River to see if they have a pattern similar to that of freshwater Atlantic stingrays. This would determine if the relatively long evolution of Potamotrygonids in fresh water that ...
9
Differential gene expression in human abdominal aortic aneurysm and aortic occlusive disease
... human AAA biopsies has consistently identified concurrent intimal atherosclerosis and most AAAs have been considered to result from atherosclerosis [5, ...and AAA are however distinct, for example diabetes ...
13
Involvement of TLR2 and TLR4, Chlamydophila pneumoniae and Mycoplasma pneumoniae in adventitial inflammation of aortic atherosclerotic aneurysm
... Aortic atherosclerotic aneurysm (AAA) is a life threat- ening condition associated with significant morbidity and mortality. The half-marks in the pathogenesis of aortic aneurysms are destruction of elastin and ...
9
Impact of poroelasticity of intraluminal thrombus on wall stress of abdominal aortic aneurysms
... An abdominal aortic aneurysm (AAA) ruptures when the mechanical stress exceeds the local wall strength. Commonly used criterion of maximum diameter is not reliable enough to assess AAA rupture risk. It has ...
13
The Viborg vascular (VIVA) screening trial of 65 74 year old men in the central region of Denmark: study protocol
... The study population of men aged 65-74 years has been selected due to its relatively high cardiovascular risk, as most studies have reported increased risk with increasing age and lower prevalences of PAD and AAA ...
6
The Relationships between Energy Balance Deviations and Adiposity in Children and Adolescents
... SecA plays an essential role in the Sec-dependent protein translocation in Esche- richia coli. Molecular modeling and experimental results indicate that the interaction among the three α -helixes in HSD of the C-terminal ...
155