accelerating factor
Protective effects of decay-accelerating factor on blast-induced neurotrauma in rats
... Background: Blast-induced neurotrauma (BINT) is the signature life threatening injury of current military casualties. Neuroinflammation is a key pathological occurrence of secondary injury contributing to brain damage ...
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Interaction between echovirus 7 and its receptor, decay-accelerating factor (CD55): evidence for a secondary cellular factor in A-particle formation.
... decay-accelerating factor (DAF) (CD55), the receptor for echovirus 7, were synthesized in the yeast Pichia ...secondary factor(s) may contribute to A-particle formation and uncoating of echovirus ...
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Dr(a ) polymorphism of decay accelerating factor Biochemical, functional, and molecular characterization and production of allele specific transfectants
... The Dra antigen belongs to the Cromer-related blood group system, a series of antigens on decay accelerating factor (DAF), a glycosyl-phosphatidylinositol-anchored membrane protein that protects host cells ...
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Coxsackieviruses B1, B3, and B5 use decay accelerating factor as a receptor for cell attachment.
... decay accelerating factor as a major cell attachment receptor for coxsackieviruses B1, B3, and ...acceleration factor on the surface of nonpermissive murine fibroblasts led only to virus attachment ...
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Interaction with Decay-Accelerating Factor Facilitates Coxsackievirus B Infection of Polarized Epithelial Cells
... All coxsackie B (CB) viruses can initiate infection by attaching to the coxsackievirus and adenovirus receptor (CAR). Although some CB isolates also bind to decay-accelerating factor (DAF), the role of DAF ...
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Synthesis of aberrant decay accelerating factor proteins by affected paroxysmal nocturnal hemoglobinuria leukocytes
... Paroxysmal nocturnal hemoglobinuria (PNH) leukocytes fail to express decay-accelerating factor (DAF) but contain DAF mRNA transcripts resembling those in normal cells. To further investigate the nature of ...
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Viral Cell Entry Induced by Cross-Linked Decay-Accelerating Factor
... Decay-accelerating factor (DAF) mediates cellular attachment for many human picornaviruses. In most cases, viral binding to DAF is itself insufficient to permit cell infectivity, with a second, functional ...
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Decay-Accelerating Factor Binding Determines the Entry Route of Echovirus 11 in Polarized Epithelial Cells
... decay-accelerating factor (DAF or CD55) at the apical surface of polarized Caco-2 cells results in rapid transport of the virus to tight junctions and in its subsequent ...
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Markedly enhanced susceptibility to experimental autoimmune myasthenia gravis in the absence of decay accelerating factor protection
... characterized by loss of acetylcholine receptors (AChR’s) due primarily to the production of anti-AChR autoantibodies. In this study we investigated whether the presence of decay- accelerating factor (DAF ...
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Decay accelerating factor protects human tumor cells from complement mediated cytotoxicity in vitro
... decay- accelerating factor (DAF), a membrane regulatory protein that protects blood cells from autologous complement ...venom factor-treated ...
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Decay accelerating factor (CD55) protects neuronal cells from chemical hypoxia-induced injury
... Decay-accelerating factor (DAF, also known as CD55), a ubiquitously expressed intrinsic complement regulatory protein, inhibits complement activation by inhibiting the function of C3/C5 convertases in both ...
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Novel Role for Decay-Accelerating Factor in Coxsackievirus A21-Mediated Cell Infectivity
... Decay-accelerating factor (DAF) is involved in the cell membrane attachment of many human enteroviruses. Presently, further specific active roles of DAF in mediating productive cell infection and in the ...
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Interaction of Decay-Accelerating Factor with Echovirus 7
... Echovirus 7 (EV7) belongs to the Enterovirus genus within the family Picornaviridae. Many picornaviruses use IgG-like receptors that bind in the viral canyon and are required to initiate viral uncoating during infection. ...
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Decay accelerating factor is expressed on vascular smooth muscle cells in human atherosclerotic lesions
... Decay-accelerating factor DAF is a constitutively expressed plasma membrane glycoprotein on blood cells and endothelium that inhibits cell surface C3/C5 convertase formation, thus inhibi[r] ...
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Increased expression of complement decay accelerating factor during activation of human neutrophils
... Using monoclonal antibodies in both direct-binding studies and flow cytometry, we found that resting neutrophils polymorphonuclear leukocytes [PMNI expressed 104 DAF molecules on their s[r] ...
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Focal and segmental glomerulosclerosis induced in mice lacking decay accelerating factor in T cells
... significantly correlated. These data are strong evidence that extra- renal DAF deficiency dictates whether FSGS ensues or not, while local DAF deficiency is of considerably less consequence. Recur- rence of proteinuria ...
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Interaction of Decay-Accelerating Factor with Coxsackievirus B3
... DAF is a member of a family of proteins that regulate complement activation by binding to and accelerating the de- cay of convertases, the central amplification enzymes of the complement cascade (5, 20, 21, 27). ...
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The HeLa cell receptor for enterovirus 70 is decay-accelerating factor (CD55).
... erating factor (DAF, CD55) is recognized as the cellular re- ceptor for at least six echovirus serotypes (3, 51) and as a receptor for coxsackieviruses B1, B3, and B5 (5, ...
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Complement receptor 2–mediated targeting of complement inhibitors to sites of complement activation
... In a strategy to specifically target complement inhibitors to sites of complement activation and dis- ease, recombinant fusion proteins consisting of a complement inhibitor linked to a C3 binding region of complement ...
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Identification of biomarkers in macrophages of atherosclerosis by microarray analysis
... decay-accelerating factor; CTRP1: C1q/TNF-related proteins-1; DEG: Differentially expressed gene; DYNC2H1: Dynein cytoplasmic 2 heavy chain 1; ER: Endoplasmic reticulum; GEO: Gene Expression Omnibus; GnRH: ...
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