Acetylcholine receptor
Wnt proteins regulate acetylcholine receptor clustering in muscle cells
... Results: In the study we systematically studied the effect of all 19 different Wnts in mammals on acetylcholine receptor (AChR) cluster formation. We identified five Wnts (Wnt9a, Wnt9b, Wnt10b, Wnt11, and ...
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Actions of vesamicol on an alpha bungarotoxin sensitive neuronal nicotinic acetylcholine receptor
... possible receptor action further we have examined for the first time the actions of vesamicol on a neuronal nicotinic acetylcholine receptor, using a tissue source that is amenable to both ...
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Sodium nitrate decreases agrin-induced acetylcholine receptor clustering
... C2C12 myoblasts were derived from mouse hind limb (gift from H. Gordon, University of Arizona) [30, 31], and are commonly used for skeletal muscle cell culture experiments. They are ideal for studying myoblast fusion to ...
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Reduction in mRNA and protein expression of a nicotinic acetylcholine receptor alpha 8 subunit is associated with resistance to imidacloprid in the brown planthopper, Nilaparvata lugens
... Target-site resistance is commonly caused by qualitative changes in insecticide target-receptors and few studies have implicated quantitative changes in insecticide targets in resistance. Here we show that resistance to ...
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Mutation (G275E) of the nicotinic acetylcholine receptor alpha 6 subunit is associated with high levels of resistance to spinosyns in Tuta absoluta (Meyrick) (Lepidoptera: Gelechiidae)
... nicotinic acetylcholine receptor alpha 6 subunit is associated with high levels of resistance to spinosyns in Tuta absoluta (Meyrick) (Lepidoptera: ...
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Association of neonatal myasthenia gravis with antibodies against the fetal acetylcholine receptor
... the acetylcholine receptor (AChR) for embryonic and adult muscle AChR were studied in 22 mothers with myasthenia gravis (MG) and in their newborns using human fetus and normal adult muscle AChR ...
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Expression of the α7 nicotinic acetylcholine receptor in human lung cells
... nicotinic acetylcholine receptor was demonstrated in the SCLC cell line NCI-H82, however no protected band was detected in the normal small airway epithelial cells (Figure ...
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Molecular determinants of allosteric modulation at the M1 muscarinic acetylcholine receptor
... Docking of the ligands was performed with MOE (Molecular Operating Environment, Chemical Computing Group, Inc.). CCh was docked manually into the receptor model with the protonated nitrogen interacting with Asp ...
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A Decoy Receptor Approach Using Nicotinic Acetylcholine Receptor Mimics Reveals Their Potential as Novel Therapeutics Against Neurotoxic Snakebite
... In parallel with structural studies on these nAChR homologues, short- and long-chain 3FTxs from snake venom, such as α-bungarotoxin from Bungarus multicinctus (many- banded krait) (Huang et al., 2013), α-cobratoxin from ...
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Antibody to acetylcholine receptor in myasthenia gravisPrevalence, clinical correlates, and diagnostic value
... Elevated amounts of antibodies specific for acetylcholine receptors were detected in 87 percent of sera from 71 patients with myasthenia gravis but not in 175 sera from individ[r] ...
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Monoclonal Antibodies Detecting Regulatory Polypepttdes of the Insect Neuronal Acetylcholine Receptor
... To verify the modulatory effect of the purified antigen on the AChR, BGTX binding to pretreated neuronal membranes was determined in the presence or absence of the purified polypeptides.[r] ...
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Lynxl and the β2V287L Mutation Affect the Stoichiometry of the α4β2 Nicotinic Acetylcholine Receptor
... specific receptor subtypes they interact with, where those receptors are located subcellularly, on which neurons, how those neurons fit into larger circuits, and finally, how those circuits control ...
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Chemical scale investigations of drug receptor interactions at the nicotinic acetylcholine receptor
... Stage VI oocytes of Xenopus laevis were employed. Oocyte recordings were made 24 to 48 h post injection in two-electrode voltage clamp mode using the OpusXpress TM 6000A (Axon Instruments, Union City, California). ...
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Evidence from the anti-idiotypic network that the acetylcholine receptor is a rabies virus receptor.
... A Lanes: 1, immunoprecipitation with polyclonal rabies virus CVS strain antibody showing multiple viral proteins; 2, immunoprecipitation with polyclonal rabies virus antibody and control[r] ...
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Association of autoantibodies against the M2 muscarinic receptor with perinatal outcomes in women with severe preeclampsia
... Abstract Background: The goal of this study was to test the hypothesis that autoantibodies against M2-muscarinic acetylcholine receptor M2-AAB are associated with severe preeclampsia and[r] ...
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Double seronegative myasthenia gravis with antiphospholipid syndrome: a case report
... nicotinic acetylcholine receptor (AChR) at the neuromuscular junction ...Muscle-specific receptor tyrosine-kinase (MuSK) is a protein associated with the AChR, playing a role in its assembly ...
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The Cholinergic Anti-inflammatory Pathway: A Missing Link in Neuroimmunomodulation
... nicotinic acetylcholine receptor α7 subunit to endotoxin chal- lenge (105) implies a critical role of the cholinergic anti-inflamma- tory pathway in regulation of peripheral ...
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MOLECULAR DOCKING STUDIES OF ZANTHOXYLUM TETRASPERMUM WIGHT AND ARN STEM BARK CONSTITUENTS AGAINST 2XNU (ACETYLCHOLINE BINDING PROTEIN)
... nicotinic acetylcholine receptor. Nicotinic acetylcholine receptors (nAChRs) are cholinergic receptors that form ligand - gated ion channels in the plasma membranes of certain neurons and on the ...
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RIC-3, a potential target for regulating cholinergic signaling and inflammation
... The nic��� acetylcholine receptor (nAChR) gene family encodes for subunits of acetylcholine gated ion channels. These receptors are expressed widely and have many ����� including an�� ���tory e�ects ...
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Effect Of Antagonization Of M4 Receptors With Tropicamide, Catalysis And Motor Changes Induced By Nitrergic Inhibition, In Mice
... muscarinic acetylcholine receptor increased interest in the modulation of striatal cholinergic signaling in order to reduce disturbances of the basal ganglia (Wess et ...
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