Actin remodeling
Drosophila Mon2 couples Oskar induced endocytosis with actin remodeling for cortical anchorage of the germ plasm
... promotes actin remodeling to form long F-actin projections at the oocyte posterior ...endocytosis-coupled actin remodeling appears to be crucial for the pole plasm anchoring, the ...
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The H3K4me3/2 histone demethylase RBR 2 controls axon guidance by repressing the actin remodeling gene wsp 1
... of actin-remodeling genes as targets of RBR-2 is interesting in the context of neurological ...the actin-remodeling genes required for axon/dendrite formation and synaptic plasticity, which ...
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The C Terminus of Rotavirus VP4 Protein Contains an Actin Binding Domain Which Requires Cooperation with the Coiled-Coil Domain for Actin Remodeling
... that actin remodeling results from the concerted action of two distinct domains, ...remodels actin microfilaments is that at least two molecules of VP4 bind to actin microfilaments through ...
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Lentiviral Nef Proteins Utilize PAK2-Mediated Deregulation of Cofilin as a General Strategy To Interfere with Actin Remodeling
... membrane ruffle formation and induction of cofilin hyperphos- phorylation downstream of PAK2 to comparable extents de- spite variable efficiencies in PAK2 association in vitro. This apparent lack of correlation between ...
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Insulin induced cortical actin remodeling promotes GLUT4 insertion at muscle cell membrane ruffles
... of actin filaments in GLUT4 translocation and their possible defects in insulin resist- ance, using L6 myotubes expressing myc-tagged ...the actin structures supporting the membrane ...affect actin ...
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Inhibition of T-Cell Receptor-Induced Actin Remodeling and Relocalization of Lck Are Evolutionarily Conserved Activities of Lentiviral Nef Proteins
... of actin remodeling, the cell surface concentration of TCR-CD3 determines the signal output in cells that undergo efficient ...on actin remodeling are potently affected by expression of all ...
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Expression of Rotavirus NSP4 Alters the Actin Network Organization through the Actin Remodeling Protein Cofilin
... subcortical actin packed into “finger-like” plasma membrane ...lar actin cytoskeleton-disrupting agent cytochalasin D, points to the possibility that NSP4 intracellular signaling remodels the actin ...
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The Enterohemorrhagic Escherichia coli effector EspW triggers actin remodeling in a Rac1 dependent manner
... Using a two-hybrid screen, we identified Kif15 as a specific partner of the full-length EspW isoform. Human Kif15 is a multimeric protein of 1,388 amino acids which belongs to the kinesin family (29). It has an N-terminal ...
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The ADF/cofilin family: actin remodeling proteins
... of actin-binding proteins expressed in all eukaryotic cells so far ...the actin cytoskeleton, for example during cytokinesis, when the actin-rich contractile ring shrinks as it contracts through the ...
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Tec29 controls actin remodeling and endoreplication during invagination of the Drosophila embryonic salivary glands
... processes: actin cytoskeletal organization and regulation of the cell ...the actin cytoskeleton during Drosophila embryogenesis and oogenesis (Guarnieri et ...for actin filament reorganization and ...
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Novel Roles of Focal Adhesion Kinase in Cytoplasmic Entry and Replication of Influenza A Viruses
... the actin cytoskeleton to the extracel- lular matrix ...the actin cortex to the ...and actin remodeling, we investigated the contribution of FAK to these processes during influenza virus in- ...
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RAC1-Mediated Actin Cytoskeleton Remodeling and Monolayer Barrier Properties of Stretched Alveolar Epithelial Cells
... Furthermore, Akt phosphorylation, shown to inhibit apoptosis (19, 20, 25, 59, 60, 176), is magnitude dependent, similar to stretch magnitude dependent PJAR formation and cell death. Others have shown that PI3K-Akt ...
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Reactive Oxygen Species Are Induced by Kaposi's Sarcoma-Associated Herpesvirus Early during Primary Infection of Endothelial Cells To Promote Virus Entry
... Primary in vitro infection of HMVEC-d cells by KSHV is con- sidered the closest model mimicking in vivo infection of endothe- lial cells. Our earlier detailed studies have highlighted the different stages of in vitro ...
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Plasma membrane localization of MLC1 regulates cellular morphology and motility
... of actin branching How does the surface expression of MLC1 induce the morphological changes of the cell via actin cytoskeletal remodeling? Previous studies reported that inhibition of the ...
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Rotavirus Spike Protein VP4 Binds to and Remodels Actin Bundles of the Epithelial Brush Border into Actin Bodies
... VP4-induced actin-remodeling specifically alters the brush border of intestinal ...VP4-induced actin bundle remodeling might have functional consequences, experiments with intestinal cells ...
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Cytoskeleton and their Molecular Structure
... There are three types of cytoskeleton, each of which plays unique roles within cells. These are actin filaments, microtubules and intermediate filaments. All have thin, fibrous structures and are polymers of basic ...
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Wang, Shuaijun (2019): Evaluation of the actin binding natural compounds Miuraenamide A and Chivosazole A. Dissertation, LMU München: Fakultät für Chemie und Pharmazie
... inhibit actin polymerization through specific binding to G-actin, thereby leading to disruption of cytoskeletal ...of actin cytoskeleton, as well as a promising antimicrofilament lead candidate for ...
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Structure and Evolution of the Actin Gene Family in Arabidopsis thaliana
... Actin is encoded by 10 genes in A. thulium: A primary goal of this study was a thorough analysis of actin gene family structure in Arabidopsis. Hybridization of actin coding s[r] ...
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Distinct Actin and Lipid Binding Sites in Ysc84 Are Required during Early Stages of Yeast Endocytosis
... on actin organization at 30°C was then analysed (Fig ...of actin organization were defined in cells: (1) both actin patches and cables; (2) only patches but these were largely polar- ized; (3) only ...
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Dynamic Remodeling of the Magnetosome Membrane Is Triggered by the Initiation of Biomineralization
... membrane remodeling mechanisms exist to achieve the distinct sizes and morphologies of organelles ...membrane remodeling, similar to the endoplasmic reticulum and mito- chondria (49, ...membrane ...
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