acute leukemia
Acute Leukemia Classification based on Image Processing and Machine Learning Techniques
... An acute leukemia diagnosis is an important challenge amongst the most Hematopathology ...of acute leukemia subtypes by using Otsu’s method to extract the ...
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Protein kinase inhibitors for acute leukemia
... In summary, molecular targeted therapy has demon- strated impressive efficacy and the development of PKIs has promising impact on acute leukemia patients. With the rapid development of biological ...
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31P MRS analysis of the phospholipid composition of the peripheral blood mononuclear cells (PBMC) and bone marrow mononuclear cells (BMMC) of patients with acute leukemia (AL)
... Data on the behavior of CPLAS in the PBMC and BMMC of acute leukemia was discussed by the authors of an earlier paper [9]. Differences in the lipid content in cell membranes were also observed between ...
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Flow Cytometric Diagnosis of Acute Leukemia and Aberrant Antigen: Sohag University Experience
... of acute leukemia including one for the isotypic matched negative control (supplied by Beckman Coulter, France), B-lineage markers (CD19, CD22, CD10, cCD79a), T cell markers: (CD2, CD3, cCD3, CD5, CD4, CD8, ...
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<p>T-lymphoid/myeloid mixed phenotype acute leukemia and early T-cell precursor lymphoblastic leukemia similarities with <em>NOTCH1</em> mutation as a good prognostic factor</p>
... phenotype acute leukemia (T/ M-MPAL) and B/myeloid mixed phenotype acute leuke- mia (B/M-MPAL) are distinct entities within the same category of leukemia of ambiguous cell ...precursor ...
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Pattern of childhood acute leukemia presentation at a tertiary hospital in Nigeria: a five-year review
... This is a retrospective cross-sectional study of children managed for acute leukemia at the paediatric department of a tertiary hospital in a 5- year period from January 2012 to January 2017. The study was ...
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Drugging the unfolded protein response in acute leukemias
... As the UPR has already been suggested as a potential oncogenic network, the therapeutic efforts to date have focused mainly on the PERK/eIF2α and IRE-1α/XBP1 signaling axes. In the case of PERK, selective ATP- ...
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Intracranial hemorrhage in adult patients with hematological malignancies
... The incidence of ICH is less common in patients with lymphoma and myeloma, among those with intracranial involvement. ICH occurred more frequently in patients with CNS involved lymphoid malignancy relative to those with ...
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Targeting histone methyltransferases and demethylases in clinical trials for cancer therapy
... selectivity over MAOs and LSD2 over 1000-fold), which is able to show a time- and dose-dependent H3K4me2 accumulation at KDM1A target genes and induction of differentiation markers in THP-1 cells with MLL trans- location ...
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Case Report B-acute lymphoblastic leukemia occurring in two pediatric patients with a history of prior Wilms tumors
... Therapy-related acute leukemia (t-AL) is an observed carcinogenesis due to the toxic side effects of ion- izing radiation and/or conventional chemotherapy for primary ...therapy-related acute myeloid ...
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Unmanipulated haploidentical in comparison with matched unrelated donor stem cell transplantation in patients 60 years and older with acute myeloid leukemia: a comparative study on behalf of the ALWP of the EBMT
... a: Acute; allo-SCT: Allogenic stem cell transplantation; ALWP: Acute Leukemia Working Party; AML: Acute myeloid leukemia; ATG: Anti-thymocyte globulins; BM: Bone marrow; Bu: Busulfan; ...
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Sex Ratio of Children Born of Leukemic Mothers
... ratio of children born of mothers with acute leukemia suggested a potential clue to genetic. changes in leukemia[r] ...
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Leukemia relapse following unmanipulated haploidentical transplantation: a risk factor analysis on behalf of the ALWP of the EBMT
... Allogeneic stem cell transplantation (allo-SCT) repre- sents a curative option for intermediate- and high-risk adult acute leukemias (AL). In the absence of a matched donor, haploidentical donors are increasingly ...
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Volume 3, Issue 4, April 2014 Page 129
... detecting leukemia is analyzing of white blood cells (WBC) where the WBC composition reveals important diagnostic information of a ...patient. Leukemia is a malignant disease (cancer) seen in people of any ...
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Myeloid Sarcoma of the peritoneum at older ages: A case report and review of literature.
... molecular analysis. The granulocytic sarcoma subclassified according to cell type into granulocytic, monoblastic or myelomonocytic and according to cell maturation into immature, mature and blastic types 5 . Pileri et al ...
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Childhood leukemia: central nervous system abnormalities during and after treatment
... Bacterial or fungal infections associated with neutropenia are common in patients with newly diagnosed or recurrent acute leukemia (32, 33). Three of our five patients with CNS infections had persistent ...
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The Philadelphia chromosome in leukemogenesis
... myeloid leukemia (CML). In leukemia cells, Ph not only impairs the physiological signaling pathways but also disrupts genomic ...distinct leukemia phenotype, which predicts both response to therapy ...
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Dual effect of oxidative stress on leukemia cancer induction and treatment
... as acute because AML progresses quickly with- out ...common acute lymphoblastic leukemia antigen (CALLA) which is a 749- amino acid type II integral membrane protein ...[99]. Acute ...
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Reliability analysis of the Chinese version of the Functional Assessment of Cancer Therapy – Leukemia (FACT-Leu) scale based on multivariate generalizability theory
... i.e., acute leukemia and chronic leukemia, based on the natural course and the cellular differentiation ...of leukemia and 53,400 deaths in 2015 ...with leukemia needs specific, ...
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Invasive fungal infection among hematopoietic stem cell transplantation patients with mechanical ventilation in the intensive care unit
... ALL: Acute Lymphoid Leukemia; AML: Acute Myeloid Leukemia; APACHE II: Acute Physiology and Chronic Health Evaluation II; BMT: Bone Marrow Transplantation; CML: Chronic Myeloid ...
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