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adipose tissue

Targeting adipose tissue

Targeting adipose tissue

... muscle tissue without carrying the Myf5 signature, for example, after chronic cold exposure or β-adrenergic stimulation ...visceral adipose tissue ...

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Heterogeneity of adipose tissue in development and metabolic function

Heterogeneity of adipose tissue in development and metabolic function

... in adipose tissue. Grandl and colleagues demonstrated that adipose depot-specific differences in the ECM regulate the differentiation of adipocyte precursor populations (Grandl et ...to ...

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Strategies for Human Adipose Tissue Repair and Regeneration

Strategies for Human Adipose Tissue Repair and Regeneration

... 3D adipose tissue is also an invaluable tool for ex vivo studies on physiological disorders, metabolic diseases and drug ...BAT tissue highly attractive for regen- erative purposes due to its ...

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NPC1 in human white adipose tissue and obesity

NPC1 in human white adipose tissue and obesity

... white adipose tis- sue (WAT) and marked adipocyte dysfunction that in- crease the risk for insulin resistance, type 2 diabetes mellitus and cardiovascular ...White adipose tissue is not only energy ...

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Age and sex variation in visceral adipose tissue

Age and sex variation in visceral adipose tissue

... Background: Adipose tissue mainly visceral fat is said to be harmful and acts as a harbinger of metabolic disorders. A changing trend is seen in the recent decades with decreasing incidence of metabolic ...

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Human adipose tissue microvascular endothelial cells secrete PPARγ ligands and regulate adipose tissue lipid uptake

Human adipose tissue microvascular endothelial cells secrete PPARγ ligands and regulate adipose tissue lipid uptake

... ferentiation cocktail or OA for several days. Although they could clearly accumulate many small lipid droplets when incubated with OA (Figure 2, B and E), this was not induced by the differentiation cocktail alone (Fig- ...

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The Role of CREB in the Liver and Adipose Tissue

The Role of CREB in the Liver and Adipose Tissue

... tissue specificity could be achieved. Similarly, Creb-ASO lead to decrease in Creb mRNA levels in both the liver and adipose tissue (Erion et al. 2009). Multiple organs in the body control glucose ...

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Role of adipose tissue in facial aging

Role of adipose tissue in facial aging

... others, it was shown that the facial preadipocytes exhibit much stronger differentiation in response to rosiglitazone, which is the agonist of the master adipogenic factor per- oxisome proliferator-activated receptor ...

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Brown adipose tissue: is it affected by intermittent hypoxia?

Brown adipose tissue: is it affected by intermittent hypoxia?

... Brown adipose tissue (BAT) function may be involved in obesity [5]. BAT produces heat through the action of uncoupling protein 1 (UCP1) [6]. During exposure to cold, UCP1 is physiologically regulated by ...

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INDUCTION OF BROWN ADIPOSE TISSUE: A REVIEW

INDUCTION OF BROWN ADIPOSE TISSUE: A REVIEW

... of adipose tissue and its types Earlier, adipose tissue was not considered as important as ...the adipose tissue as an endocrine organ as it releases many complex products for ...

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Phenylalanine kinetics in human adipose tissue

Phenylalanine kinetics in human adipose tissue

... modest. Adipose tissue is known to be more sensitive to the antilipolytic effects of insulin than are muscle and liver with respect to the effects of insulin on glucose me- tabolism (50); significant ...

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Recent progress in the study of brown adipose tissue

Recent progress in the study of brown adipose tissue

... Obesity is defined not only as an excess of body weight, but also an increased adipose tissue accretion to the extent that health may be adversely affected. The anti-obesity medication phentermine and ...

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The influence of perivascular adipose tissue on vascular homeostasis

The influence of perivascular adipose tissue on vascular homeostasis

... surrounding adipose tissue (for eg, the coronary PVAT within epicardial fat), or often absent (cerebral or ...categorize adipose tissue as either subcutaneous (SAT) or visceral (VAT), the PVAT ...

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Insulin resistance causes inflammation in adipose tissue

Insulin resistance causes inflammation in adipose tissue

... adipose tissue. Using a mouse model that combines genetically induced, adipose-specific insulin resistance (mTORC2-knockout) and diet-induced obesity, we found that insulin resistance causes local ...

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Characterization of immune cells in psoriatic adipose tissue

Characterization of immune cells in psoriatic adipose tissue

... human adipose have generally assumed that characteristic markers of im- mune cells described in animal models or in other hu- man tissues can be applied similarly to adipose ...human adipose immune ...

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Insulin action in human adipose tissue in acromegaly

Insulin action in human adipose tissue in acromegaly

... utilization but not on lipolysis is impaired in adipose tissue of acromegalic patients because of a postreceptor defect. After glucose ingestion, the resistance to insulin in acromegaly is further enhanced ...

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Obesity is associated with macrophage accumulation in adipose tissue

Obesity is associated with macrophage accumulation in adipose tissue

... alters adipose tissue metabolic and endocrine function and leads to an increased release of fatty acids, hormones, and proinflammatory molecules that contribute to obesity associated ...in adipose ...

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The role of endoplasmic reticulum in human adipose tissue

The role of endoplasmic reticulum in human adipose tissue

... vivo adipose tissue or murine adipocyte cells lines, no work has examined mediators of ER stress and the ER stress pathway in human differentiated adipocytes, in ...within adipose tissue to ...

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Obesity induced inflammatory changes in adipose tissue

Obesity induced inflammatory changes in adipose tissue

... lean, adipose tissue, and that these clusters became larger and more numerous as the animals aged and gained ...white adipose tissue were not expressed in these ...

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Epicardial adipose tissue in patients with heart failure

Epicardial adipose tissue in patients with heart failure

... So far, the role of EAT and its contribution to the devel- opment of cardiac pathology is quite ambiguous. There is growing evidence of a close functional and anatomical relationship between the adipose ...

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