adjacent normal tissues
Detection of reactive oxygen metabolites in malignant and adjacent normal tissues of patients with lung cancer
... Ischemia is the major cause of superoxide generation in cancer tissues. Ischemia leads to glucose and adenosine tri- phosphate (ATP) depletion, which in turn leads to a de- crease in sodium-potassium ATPase (Na-K ...
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Original Article The role of ATP8A1 in non-small cell lung cancer
... tumor tissues and the adjacent normal tissues from surgeries of NSCLC patients in our hospital, among which 15 cases were found with lymph node metastasis while the other 10 were ...NSCLC ...
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Original Article Application value of ultrasound contrast in gastric cancer examinations and its correlation with microvessel density
... cancerous tissues and adjacent normal tissues were compared, including enhanced time (ET), time to peak (TTP), and wash in rates ...cancer tissues was ...cancerous tissues and ...
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Low expression of LOC285194 is associated with poor prognosis in colorectal cancer
... tumor tissues compared with adjacent normal tissues (p < ...with normal intestinal mucous cell line using RT-qPCR assays (p = ...
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Original Article ADAM12 expression predicts clinical outcome in estrogen receptor-positive breast cancer
... evaluate the role of ADAM12 expression in overall survival (OS) of patients. Cox-regression analysis was performed to judge if ADAM12 could serve as a prognostic marker in breast cancer. Results: The level of ADAM12 was ...
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Original Article Curcumin suppresses gastric cancer biological activity by regulation of miRNA-21: an in vitro study
... of adjacent and cancer tissues to measure miRNA-21 expression by ISH, evaluating pathology by H&E staining and measuring PTEN protein expres- sion by ...with adjacent normal ...
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Original Article RNA-binding protein RBM38: acting as a tumor suppressor in colorectal cancer
... CRC tissues and 23 tumor-adjacent normal ...cancer tissues, positive in 46 of 90 ...tumor-adjacent normal tissues were showed in Figure ...
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Functional role of eukaryotic translation initiation factor 4 gamma 1 (EIF4G1) in NSCLC
... Eukaryotic translation initiation factor 4 gamma 1(EIF4G1) is related to tumorigenesis and tumor progression. However, its role and the underlying mechanisms in the regulation of tumor development in non–small cell lung ...
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Gankyrin sustains PI3K/GSK-3β/β-catenin signal activation and promotes colorectal cancer aggressiveness and progression
... CRC tissues and 51 normal colorectal tissues, Gankyrin mRNA was identified to be significantly upregulated in CRC tissues compared with normal tissues (Figure 1A, Supplementary ...
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Original Article Gab2 is a novel prognostic factor for colorectal cancer patients
... CRC tissues compared with the matched adjacent non-tumor tissues using real-time quantitative reverse transcription PCR (qRT-PCR) and western blotting, ...CRC tissues relative to ...
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Overexpression of HHLA2 in human clear cell renal cell carcinoma is significantly associated with poor survival of the patients
... ccRCC tissues compared with that in adja- cent normal tissues based on TCGA data, and the HHLA2 expression at mRNA level was positively and significantly correlated with PD-L1, PD-L2, B7-H6, but ...
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... cancer tissues, compared to that in the adjacent normal ...cancer tissues had an elevated expression level of BRD4, in contrast to the adjacent normal ...
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Original Article Correlation of LARP1 and E-cadherin expression with prognosis of intrahepatic cholangiocarcinoma
... with adjacent normal tissues and 20 normal bile duct ...tumor tissues were significantly higher compared with corresponding adjacent normal tissues and ...
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MicroRNA expression profiles predict progression and clinical outcome in lung adenocarcinoma
... expressed by class comparison (Table S1). Among these 185 miRNAs, 133 miRNAs (71.9%) were upregulated, and the remaining 52 miRNAs (28.1%) were downregulated. In relation to the fold change, 48 differentially expressed ...
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Original Article Altered TRAF3 and IKKα expression associated with advanced tumor stage and metastasis and poor prognosis of intrahepatic cholangiocarcinoma
... 50 adjacent normal tissues and 16 normal bile duct tissues were detected by immunohistochemistry and in situ ...in normal epithelial tissues and adjacent ...
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Original Article Increased expression of the lncRNA PVT1 promotes tumorigenesis in non-small cell lung cancer
... NSCLC tissues and 3 lung cancer cell lines was measured by quantitative Real-time PCR ...NSCLC tissues and lung cancer cells when compared with corresponding adjacent normal tissues and ...
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miRNA-135a promotes hepatocellular carcinoma cell migration and invasion by targeting forkhead box O1
... cells, normal liver cells, HCC tissues and adjacent normal live tissues and investigated the effect of miR-135a overexpression on HCC cell migration and ...
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Evaluation of the Association between Androgen Receptor and AURKA and Its Prognostic Value in Gastric Cancer
... Difference in expression of AURKA between gastric tumors and adjacent non-tumor tissues or normal tissues was compared by Independent samples Mann-Whitney U test. Correlation was computed ...
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Minichromosome maintenance protein 2 correlates with the malignant status and regulates proliferation and cell cycle in lung squamous cell carcinoma
... LUSC tissues compared with paired adjacent normal lung tissues (Figure ...LUAD tissues, LUSC tissues and normal lung ...with normal lung tissues or LUAD ...
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miR-141-3p is a key negative regulator of the EGFR pathway in osteosarcoma
... Methods: Western blot, real-time PCR and immunohistochemical were used to detect the expression of EGFR and miR-141 in osteosarcoma tissues and cells. The correlation between miR-141 and the grading of ...
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