Allergic Inflammation
Microbial Regulation of Allergic Inflammation
... Previous studies have shown that antibiotic-treated animals develop allergic responses (Bashir et al. 2004) and antibiotic use in children is associated with increased risk of developing asthma later in life ...
206
Periostin promotes chronic allergic inflammation in response to Th2 cytokines
... induces allergic skin inflammation in a Stat6-dependent manner in ...of allergic inflammation, we adopted a mouse model of allergic skin inflammation by epicutaneous ...
12
Complement Component 3C3 and C3a Receptor Are Required in Chitin Dependent Allergic Sensitization to Aspergillus fumigatus but Dispensable in Chitin Induced Innate Allergic Inflammation
... innate allergic inflammation and may promote sensitization to fungal ...dependent allergic sensitization to Aspergillus requires C3aR signaling, which suppresses regulatory dendritic cells and T ...
10
Polycomb repressive complex 2 is a critical mediator of allergic inflammation
... allergic inflammation. Finally, we believe that the suppression of inflammation associated with EZH2 inhibition could also be used to treat other conditions in which activated T or B lymphocytes ...
18
Recurrent airway obstruction in horses – an allergic inflammation: a review
... et al., 1990a,b; Davis and Rush, 2002). Inflammation leads to mucus hypersecretion, ciliary dysfunction, and changes in the composition and biophysical properties of airway secretions. There are con- flicting ...
13
The Effects of PM2.5 on Allergic Inflammation in Mast Cell Deficient Mice
... In contrast to our findings, it has been reported that systemically sensitized juvenile OVA-allergic BALB/cJ mice do not display enhanced eosinophil infiltration or AHR following CAPs exposures [588]. This study ...
211
Neuro immune crosstalk and allergic inflammation
... Furthermore, a recent study demonstrated that ILC2s also contact enteric adrenergic neurons in the intestine. β2AR signal- ing suppresses ILC2 proliferation cell-intrinsically and suppress- es ILC2-mediated ...
9
Soluble CD93 in Serum as a Marker of Allergic Inflammation
... with allergic diseases (at least one of these: AR, CSU, and BA) at the Allergy Asthma Center of the Severance Hospital in Seoul, Korea from May 2014 to September ...severe allergic reaction, anaphylaxis; ...
6
The intestinal microbiota contributes to the ability of helminths to modulate allergic inflammation
... exert immuno-modulatory activity in an indirect manner as well. Helminth-induced alterations to the gut microbiota are of partic- ular interest because this diverse and complex community can have a profound impact on ...
14
Sirtuin 2 enhances allergic asthmatic inflammation
... exacerbated allergic response, with elevated CCL17 production and enhanced goblet cell hyper- ...of allergic inflammation in asthma and identify a role for Sirt2 in regulating a proasthmatic ...
16
The IL-17 receptor IL-17RE mediates polyIC-induced exacerbation of experimental allergic asthma
... of allergic inflammation of the lung and airway hyper-responsiveness (AHR) [5, 23– ...of allergic airway inflammation and ...once allergic airway inflammation has been ...
8
PubMedCentral-PMC4976002.pdf
... of allergic inflammation and asthma Many animal model studies have documented the ability of inhaled UFP and NP to act as pro-allergic adjuvants, boosting the allergic immune response to ...
26
A pathophysiological role of PDE3 in allergic airway inflammation
... Some promising results have been reported for the dual PDE3/4 inhibitor RPL554, which is already in a phase II clinical trial for asthma (21). Although RPL554 is described as a dual inhibitor, it is 3,750-fold more ...
17
Single systemic administration of Ag85B of mycobacteria DNA inhibits allergic airway inflammation in a mouse model of asthma
... study, mRNA expression levels of IL-10 and transforming growth factor- β in lymph node cells obtained from mice immunized with Ag85B DNA were much higher than those in lymph node cells obtained from control mice after in ...
9
An ovine tracheal explant culture model for allergic airway inflammation
... The use of in vitro models, in particular primary cell cultures, has greatly contributed to our understanding of molecular pathways in allergic inflammation. However, asthma is a complex disease, and in ...
9
Effects of <em>Caryota mitis</em> profilin-loaded PLGA nanoparticles in a murine model of allergic asthma
... with allergic asthma were treated with PLGA-encapsulated rCmP utilizing a rCmP/Al(OH) 3 vaccine group and a blank PLGA nanoparticle group as ...mitigated allergic inflammation, and the former ...
10
Endotoxin Is Not Essential for the Development of Cockroach Induced Allergic Airway Inflammation
... airway allergic in- flammation and the role of endotoxin in CR extract are not clearly understood in regards to the development of airway ...airway allergic inflammation in ...Airway allergic ...
10
Comprehensive evaluation of genetic variation in S100A7 suggests an association with the occurrence of allergic rhinitis
... Although allergic rhinitis primarily affects the upper air- ways, it also has systemic manifestations, and it is well known that allergic rhinitis is closely related to asthma ...with allergic ...
7
Updates in the treatment of ocular allergies
... A good patient history and clinical examination are essen- tial and can solve the nature of the eye disease in many cases. When the diagnosis is not clear, some laboratory examinations are needed. When an infection could ...
10
Regulatory B cells in allergic asthma and schistosomiasis : controlling inflammation
... airway inflammation and EAE ...against allergic reactions in both anaphylaxis and allergic airway inflammation models in an IL-10 dependent manner ...
171