alpha-Helical
Graph representation of high-dimensional alpha-helical membrane protein data
... a alpha-helical structure is constructed, these motifs are required for filling the gaps in the physical and structural ...of alpha-helices into two-dimensional images which they called ...
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Mutagenic analysis of human immunodeficiency virus type 1 Vpr: role of a predicted N-terminal alpha-helical structure in Vpr nuclear localization and virion incorporation.
... predicted alpha-helical struc- ture located near the N terminus of ...predicted alpha helix contains a notable acidic hydrophilic face and an aliphatic hydrophobic face, as shown in ...predicted ...
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A Sequential Segment Based Alpha-Helical Transmembrane Protein Alignment Method
... Alpha-helical transmembrane protein (αTMP) is one of the two major categories of transmembrane protein (TMP). They are abundant existing in eukaryotic cells and involved in many biological processes. The ...
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Alpha helical regions of the protein molecule as organic nanotubes
... the alpha-helix (Figure ...an alpha-helix: the step of the helix, its radius, and the effective number of peptide groups on the turn of the ...long alpha-helical regions of light faction of ...
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Characterisation of three alpha helical antimicrobial peptides from the venom of Scorpio maurus palmatus
... Characterisation of three alpha-helical antimicrobial peptides from the venom of Scorpio maurus palmatus.. HARRISON, Patrick L., ABDEL-RAHMAN, Mohamed A., STRONG, Peter, TAWFIK, Mohamed [r] ...
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Dynamic allostery of protein alpha helical coiled-coils
... Alpha helical coiled-coils appear in many important allosteric proteins such as the dynein molecular motor and bacteria chemotaxis transmembrane receptors. As a mechanism for transmitting the information of ...
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Novel delivery system for T-oligo using a nanocomplex formed with an alpha helical peptide for melanoma therapy
... Abstract: Oligonucleotides homologous to 3′-telomere overhang (T-oligos) trigger inherent telomere-based DNA damage responses mediated by p53 and/or ATM and induce senescence or apoptosis in various cancerous cells. ...
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Hepatitis C Virus Core Protein Is a Dimeric Alpha-Helical Protein Exhibiting Membrane Protein Features
... Hepaciviruses core proteins are unique among the Flaviviri- dae. The results reported here clearly show that HCV core protein behaves as a dimeric ␣ -helical protein as was previ- ously shown for other members of ...
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Equilibrium and Kinetic folding properties of alpha-helical Greek key protein domains
... While the determinants of two-state folding kinetics are still ambiguous, Baker et. al. have suggested the topology as one of the critical determinants for homologous two-state proteins 9; 25 . The contact order (CO ...
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Disruption of prion rods generates 10-nm spherical particles having high alpha-helical content and lacking scrapie infectivity.
... have been impeded by its lack of solubility under conditions in which infectivity is retained. Among the many detergents examined, only treatment with the ionic detergent sodium dodecyl sulfate (SDS) or Sarkosyl followed ...
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Conformational dynamics is more important than helical propensity for the folding of the all alpha-helical protein Im7
... lowest helical propensity of all the helices and this led to considerations of whether it is the last helical element to form because it has the lowest helix propensity, or because there are specific ...
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The role of the Cronobacter sakazakii ProP C-terminal coiled coil domain in osmotolerance
... Culham et al. [5] first described the E. coli ProP as harbouring unusual structural features which appeared unique within the transporter superfamily. This study predicted the formation of an alpha helical ...
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KDM1A microenvironment, its oncogenic potential, and therapeutic significance
... small alpha helical domain; DNMT1: DNA methyltransferase 1; CoREST: RE1‑silencing transcription factor (REST) corepressor; NuRd: Mi‑/nucleosome remodeling and deacetylase; AR & ER: androgen & ...
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Index Catalog // Carolina Digital Repository
... Previous published work had shown that truncation of the first 24 residues of HBHA results in a loss of secondary structure 16 . Therefore, a construct starting at residue 20 (alanine) was designed, since a truncation at ...
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CapZ-lipid membrane interactions: a computer analysis
... To detect lipid membrane binding and hydrophobic motifs, and potentially antigenic regions, a window size of 11 residues was employed. The algorithm for detecting putative lipid-binding hydrophobic polypeptide sequence ...
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Structure of 2G12 Fab2 in Complex with Soluble and Fully Glycosylated HIV-1 Env by Negative-Stain Single-Particle Electron Microscopy
... For CCR5, this is an ⬃19residue portion with a predicted alpha-helical structure approximately at residues 10 to 14, where interaction with the base of V3 Journal of Virology Downloaded [r] ...
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Detecting Periodicity Associated with the Alpha Helix Structure Using Fourier Transform
... quency of N 3.6 in the protein sequence. We investi- gated whether this periodical signal of frequency N 3.6 was detectable in protein sequence. First, the protein se- quence was translated into a sequence of numerical ...
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Design and Analysis of High Speed Helical Gear with Different Helical Angles
... for helical gears is ...changing helical angle from 20 degrees to 45 and 15 degrees respectively and also analyzing these models with another two different materials and then finding which material is most ...
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All-Atom Model for Stabilization of α-Helical Structure in Peptides by Hydrocarbon Staples
... experimentally and theoretically supported. 48 – 52 We did not classify the “decoy” state as part of the denatured state, but using a different theoretical framework for thermodynamic evaluation this could have been the ...
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Finite amplitudes helical waves on the surface of the conducting fluid earth core as an example of the self-exciting homopolar heterogeneous dynamo
... Abstract. Helical waves of the finite amplitude on a surface of the fluid conducting Earth core are examined for genera- tion of the magnetic ...the helical surface wave structure on its ...the ...
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