amino acid transporter
Original Article Positive regulation of placentation by L-amino acid transporter-1 (lat1) in pregnant mice
... placenta. Amino acid transport is critical for fetal growth, not only as nutrients but also as regulators for cell motility and function during implanta- tion and placentation ...twenty amino ...
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NHEVNAT: an H+ V ATPase electrically coupled to a Na+:nutrient amino acid transporter (NAT) forms an Na+/H+ exchanger (NHE)
... of amino acid transporters) group of the NSF has been cloned and designated, AgNAT6 (Anopheles gambiae nutrient amino acid transporter 6) ...new transporter from ...
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Amino acid transporter SLC7A11/xCT at the crossroads of regulating redox homeostasis and nutrient dependency of cancer
... nutrient transporter frequently overexpressed in human cancers is the cystine/ glutamate antiporter solute carrier family 7 member 11 (SLC7A11; also known as ...important amino acid ...
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Correlation between 18F-1-amino-3-fluorocyclobutane-1-carboxylic acid (18F-fluciclovine) uptake and expression of alanine-serine-cysteine-transporter 2 (ASCT2) and L-type amino acid transporter 1 (LAT1) in primary prostate cancer
... serine-cysteine transporter 2 (ASCT2) for system ASC and sodium-independent L-type amino acid transporter 1 (LAT1) for system ...these amino acid transporters has been shown to ...
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K+ amino acid transporter KAAT1 mutant Y147F has increased transport activity and altered substrate selectivity
... neutral amino acid transporter Our hypothesis that KAAT1 is a System B type co- transporter (Stevens, 1992) is supported by the interaction between lysine and KAAT1 at pH values of ...an ...
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Identification and functional characterization of a novel arginine/ornithine transporter, a member of a cationic amino acid transporter subfamily in the Trypanosoma cruzi genome
... the amino acid/auxin permease (AAAP) family according to the Transporter Classifica- tion Database (TCDB), a curated dataset resource com- posed of transporter sequences from various organisms ...
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Sodium-Dependent Neutral Amino Acid Transporter Type 1 Is an Auxiliary Receptor for Baboon Endogenous Retrovirus
... neutral amino acid transporter type 2 (hASCT2) ...neutral amino acids and is a member of a glutamate transporter superfamily ...
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Modulation of ecotropic murine retroviruses by N-linked glycosylation of the cell surface receptor/amino acid transporter.
... mCAT-1 transporter expression, cells with wild-type glycosylated mCAT-1 had only approximately 50% as many sites for gp70 binding as cells with unglycosylated ...CAT-1 transporter that does not bind virus, ...
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Association study of polymorphisms in the neutral amino acid transporter genes SLC1A4, SLC1A5 and the glycine transporter genes SLC6A5, SLC6A9with schizophrenia
... Neutral amino acid transporters (ASCTs), which transport neutral amino acid (alanine, serine, cysteine and thre- onin) were identified based on nucleotide sequence homology to the EAATs ...The ...
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The cationic amino acid transporter 2 is induced in inflammatory lung models and regulates lung fibrosis
... Since CAT2 was not involved in inflammation, we hypothesized that it would be involved in lung fibrosis. This is based on the following: 1) CAT2 is upregulated in bleomycin-induced pulmonary fibrosis [19] and 2) argi- ...
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<p>Association study of the excitatory amino acid transporter 2 (EAAT2) and glycine transporter 1 (GlyT1) gene polymorphism with schizophrenia in a Polish population</p>
... Glycine plays an important role in the CNS development, and it is also a required co-agonist along with glutamate for NMDAR activation process. The availability of glycine, as well as its uptake from the synaptic cleft, ...
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Identification of Novel Inhibitors of the Amino Acid Transporter B0AT1 (SLC6A19), a Potential Target to Induce Protein Restriction and to Treat Type 2 Diabetes
... neutral amino acids in the intestine causes an increased amino acid load in the lumen of the intestine, which triggered the release of the two incretins glucagon-like peptide 1 (GLP-1) and gastric ...
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Altered activity of the system A amino acid transporter in microvillous membrane vesicles from placentas of macrosomic babies born to diabetic women
... [14C]-methylaminoisobutyric acid at 30 s (initial rate, a measure of system A activity) was 49% lower into FM vesicles than into control vesicles (P < ...the transporter with no change in ...
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Envelope-binding domain in the cationic amino acid transporter determines the host range of ecotropic murine retroviruses.
... By exchanging portions of cDNAs encoding the permissive mouse and nonpermissive human transporters and examining their abilities to specify virus infection upon expression in human 293 c[r] ...
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Characterization of the Candida albicans Amino Acid Permease Family: Gap2 Is the Only General Amino Acid Permease and Gap4 Is an S-Adenosylmethionine (SAM) Transporter Required for SAM-Induced Morphogenesis
... general amino acid permease and is able to transport most amino ...of amino acid uptake for this human fungal ...specific amino acid permeases are also expressed under ...
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Proteomic profiling of breast cancer metabolism identifies SHMT2 and ASCT2 as prognostic factors
... of amino acid transporters, of which ASC amino-acid transporter 2 (ASCT2), also named solute carrier family 1 member 5 (SLC1A5), belongs to the most ubiquitously expressed glutamine ...
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11C-Methionine-PET in Multiple Myeloma: Correlation with Clinical Parameters and Bone Marrow Involvement
... 43 patients with MM underwent both MET- and FDG-PET/CT for staging or re-staging within 3±2 days. Scans were compared on a patient and on a lesion basis. Tracer uptake was correlated with the degree of bone marrow (BM) ...
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Comparative sequence analysis and tissue localization of members of the SLC6 family of transporters in adult Drosophila melanogaster
... potassium-coupled amino acid transporter-1 (KAAT1) (Castagna et ...cation-anion-activated amino acid transporter/channel-1 (CAATCH1) (Feldman et ...aegypti amino ...
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N System Amino Acid Transport at the Blood CSF Barrier
... Glutamine is transported by the Na'-independent, leucine-preferring L-system amino acid transporter from blood to CSF at the choroid plexus Segal et al ., 1990 and from blood to brain at[r] ...
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Dorsal root ganglia in Friedreich ataxia: satellite cell proliferation and inflammation
... excitatory amino acid transporter 1, ATP-sensitive inward rectifier potassium channel 10, and cytosolic ferritin), gap junctions (connexin 43), basement membranes (laminin), mitochondria (ATP ...
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