An Open Label Randomised Control Trial
Comparison of delayed cord clamping and umbilical cord milking in late preterm and term Infants – An Open Label Randomised Control Trial.
... AN OPEN LABEL RANDOMISED CONTROL TRIAL” was my original work in the Department of Neonatology, Madras medical college, Chennai under the guidance and supervision of ...
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Randomised Ambulatory Management of Primary Pneumothorax (RAMPP): protocol of an open-label, randomised controlled trial
... The Randomised Ambulatory Management of Primary Pneumothorax trial is a multicentre, randomised controlled trial comparing ambulatory management with standard care, specifically designed to ...
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Dexmedetomidine vs haloperidol in delirious, agitated, intubated patients: a randomised open label trial
... that control of agitation when the infusion rate is increased may take longer in comparison to ...our trial as a prelude to a larger double-blind study, in which (to preserve blinding) both study drugs ...
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Spray on skin for diabetic foot ulcers: an open label randomised controlled trial
... diabetes control, in- fection extent, antibiotic efficacy, adherence to off- loading and psychosocial issues are all factors that affect healing and may compromise the validity of testing a novel intervention to ...
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Docetaxel versus active symptom control for refractory oesophagogastric adenocarcinoma (COUGAR 02): an open label, phase 3 randomised controlled trial
... multicentre, open-label, randomised, controlled phase 3 trial was designed by the COUGAR-02 Trial Management Group under the auspices of the Upper Gastrointestinal Cancer Clinical ...
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Glibenclamide and metfoRmin versus stAndard care in gEstational diabeteS (GRACES): a feasibility open label randomised trial
... an open-label feasibility study between 1st August 2014 and 31st October 2015 in antenatal clinics at 5 NHS hospitals in Scotland, ...glycaemic control despite maximum tolerated dose of metformin, ...
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European trial of free light chain removal by extended haemodialysis in cast nephropathy (EuLITE): A randomised control trial
... EUropean trial of free LIght chain removal by exTEnded haemodialysis in cast nephropathy (EuLITE) trial is a prospective, randomised, multicentre, open label clinical trial to ...
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Clinical and cost effectiveness analysis of an open label, single centre, randomised trial of spinal cord stimulation (SCS) versus percutaneous myocardial laser revascularisation (PMR) in patients with refractory angina pectoris: The SPiRiT trial
... UK trial-based analysis concluded that the technology, with an incremental cost per quality-adjusted life year gained (QALY) over 12 months of over £200,000, was not cost-effective in comparison to optimal medical ...
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Concurrent once-daily versus twice-daily chemoradiotherapy in patients with limited-stage small-cell lung cancer (CONVERT): an open-label, phase 3, randomised, superiority trial
... Between April 7, 2008, and Nov 29, 2013, we recruited 547 patients from 73 centres in eight countries. We randomly assigned 274 patients to receive twice-daily chemoradiotherapy and 273 to receive once-daily chemo- ...
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The Leeds Evaluation of Efficacy of Detoxification Study (LEEDS) project: An open-label pragmatic randomised control trial comparing the efficacy of differing therapeutic agents for primary care detoxification from either street heroin or methadone [ISRCTN07752728]
... There is no evidence base to advise the most effective length of reducing regimen in achieving abstinence. Com- mon reducing regimens vary between 4 and 14 days. Therefore the reducing regimen of buprenorphine will be at ...
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Effects of antiplatelet therapy after stroke due to intracerebral haemorrhage (RESTART) : a randomised, open label trial
... The intervention of starting antiplatelet therapy was restricted to the use of one or more of oral aspirin, dipyridamole, or clopidogrel, begun within 24 h of randomisation with doses determined at the discretion of the ...
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Evaluating the use of fibrin glue for sealing low output enterocutaneous fistulas: study protocol for a randomized controlled trial
... control group (P = 0.0127) [13]. The unpublished data of the pilot study demonstrated that closure rates were 80 % (60/75) in the PRFG group and 50 % (35/70) in the control group during the 14-day ...
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The Norwegian tenecteplase stroke trial (NOR-TEST): randomised controlled trial of tenecteplase vs. alteplase in acute ischaemic stroke
... Intra-arterial embolectomy: Periodic safety review is performed after each 30 enrolled patients (15 per group). Based on data from the literature on the frequency of SICH in trials or clinical series of endovascular ...
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Early prolonged ambulatory cardiac monitoring in stroke (EPACS): an open-label randomised controlled trial
... patients randomised to the implantable recorder found that increased age was the only clinical feature that was independently associ- ated with increased incidence of PAF during follow-up ...
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Management of metastatic colorectal cancer patients: guidelines of the Italian Medical Oncology Association (AIOM)
... III trial of irinotecan/5-FU/leucovorin (FOLFIRI) or oxaliplatin/5-FU/ leucovorin (mFOLFOX6) with bevacizumab (BV) or cetuximab (CET) for patients (pts) with KRAS wild-type (wt) untreated metastatic adenocarcinoma ...
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FortiColos – a multicentre study using bovine colostrum as a fortifier to human milk in very preterm infants: study protocol for a randomised controlled pilot trial
... To make a preliminary test of the effects of the inter- vention with BCF, clinical and paraclinical outcomes will be compared between the two groups. The estimates will be presented as relative risk and absolute risk ...
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<p>Optimal Management of First-Line Advanced Renal Cell Carcinoma: Focus on Pembrolizumab</p>
... III trial against IFN- α , demonstrated signi fi cant improvement in median progression-free survival (PFS) (11 vs 5 months), with a hazard ratio (HR) of ...placebo-controlled trial, improved PFS in ...
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Concurrent once-daily versus twice-daily chemoradiotherapy in patients with limited-stage small-cell lung cancer (CONVERT): an open-label, phase 3, randomised, superiority trial.
... Methods The CONVERT trial was an open-label, phase 3, randomised superiority trial. We enrolled adult patients (aged ≥18 years) who had cytologically or histologically confirmed ...
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Associations between deepness of response and clinical outcomes among Japanese patients with metastatic colorectal cancer treated with second-line FOLFIRI plus cetuximab
... response was assessed by the investigator using computed tomography every 8 weeks ( ± 2 weeks) until disease pro- gression. Disease progression was defined as an increase in the sum of the longest tumor diameters by 20% ...
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Lenalidomide maintenance versus observation for patients with newly diagnosed multiple myeloma (Myeloma XI): a multicentre, open-label, randomised, phase 3 trial.
... XI trial, a separate group of patients received vorinostat plus lenalidomide in the maintenance randomisation because of a protocol amendment, and the outcomes of these patients will be reported ...
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