Ancient DNA (Archaeology)
Ancient DNA and the rewriting of human history: be sparing with Occam’s razor
... in ancient DNA (aDNA) technology are now beginning to make this more direct approach possible, facilitated by new sequencing technologies that are now capable of gen- erating gigabases of data at moderate ...
8
Ancient DNA from Human and Animal
... on ancient DNA (aDNA) has the potential to enable molecular biologists and archeologists to decipher certain aspects of history by direct looking into the ...modern DNA and postmortem DNA ...
6
Unlocking the origins and biology of domestic animals using ancient DNA and paleogenomics
... analyze ancient DNA from an extinct progenitor of a domestic species, when they sequenced mtDNA from aurochs (Bos primigen- ius), wild cattle that ranged across Eurasia during the Pleistocene and early ...
20
A new model for ancient DNA decay based on paleogenomic meta analysis
... long-term DNA preservation, but we offer some caveats: fragmentation through depurination is a well-characterized process (63) and we do not propose that it is irrelevant for long-term DNA ...many ...
12
Paleogenomics: reconstruction of plant evolutionary trajectories from modern and ancient DNA
... Novel scientific insights in paleogenomics that merge synchronic and allochronic approaches The evolution of modern species can be investigated in de- tail through the analysis of ancient genomes. The indirect ...
17
Schmutzi: estimation of contamination and endogenous mitochondrial consensus calling for ancient DNA
... of ancient DNA (aDNA) have enabled the study of ancient ...endogenous DNA begins to degrade and accumulates chemical ...of ancient molecules [2]. Further, when extracting DNA ...
18
Ancient DNA in Archaeologically Charred Zea Mays L: Prospects and Limitations
... of ancient DNA analyses owing to the exponential copying of small or highly deteriorated fragments of DNA, which then allowed for the preservation, sequencing and analysis of that remnant ...quaagga ...
150
Paging through history: Parchment as a reservoir of ancient DNA for next generation sequencing
... Parchment represents an invaluable cultural reservoir. Retrieving an additional layer of information from these abundant, dated livestock-skins via the use of ancient DNA (aDNA) sequencing has been mooted ...
7
Assessing the Fidelity of Ancient DNA Sequences Amplified From Nuclear Genes
... of ancient DNA has relied almost exclusively on mitochondrial DNA (mtDNA) se- ...of ancient nuclear DNA (nuDNA) sequences, thereby allowing the characterization of genetic loci directly ...
9
Quantifying and reducing spurious alignments for the analysis of ultra-short ancient DNA sequences
... human DNA that was sheared to short frag- ments of similar size to those in ancient ...details, DNA was extracted from the blood of a healthy human donor using the Gentra Puregene Blood Kit ...of ...
11
Sometimes Hidden but Always There: Assumptions Behind Demographic Inference from Ancient DNA Data
... Similar criticism applies to tools commonly used in demographic inference using modern and ancient DNA such as STRUCTURE [24], ADMIXTURE [25], Finestructure, and Chromopainter [26]. These tools vary in ...
21
Unravelling the complexity of domestication: a case study using morphometrics and ancient DNA analyses of archaeological pigs from Romania
... while ancient DNA techniques are now commonly used to identify population shifts through time, GMM methods allow for the study of both size and shape changes over time and space, and have already ...
7
Crosslinks Rather Than Strand Breaks Determine Access to Ancient DNA Sequences From Frozen Sediments
... in DNA obtained from Siberian permafrost (permanently frozen soil) ranging from 10,000 to 400,000 years in ...sedimentary DNA to be severely modified by interstrand crosslinks; single- and double-stranded ...
5
Novel substrates as sources of ancient DNA: : prospects and hurdles
... extract DNA from lithics as early as the ...satellite DNA from a 2200 year-old stone tool from British Columbia using nested PCR, while Hardy et ...and DNA within the microcracks of stone tools, and ...
27
Paging through history : parchment as a reservoir of ancient DNA for next generation sequencing
... protected from both high temperatures and fluctuating humidity. Indeed, the number of skins is truly staggering, even if, as is likely, a high percentage of documents have been destroyed. In the UK alone, assuming the ...
25
Ancient DNA Resolves Identity and Phylogeny of New Zealand’s Extinct and Living Quail (Coturnix sp )
... Amplified DNA products were obtained using the same ...of DNA was amplified by polymerase chain reaction (PCR) in 10 ul volumes containing 50 mM Tris-Cl pH ...
8
Ancient DNA elucidates the controversy about the flightless island hens (Gallinula sp.) of Tristan da Cunha
... a NucleospinH kit (Macherey-Nagel). Subsequently these products were sequenced either in-house on a Megabace TM 1000 DNA Analysis System (Amersham), or on a 3730xl DNA analyzer (Applied Biosystems) at ...
8
Bona fide colour: DNA prediction of human eye and hair colour from ancient and contemporary skeletal remains
... Previous ancient DNA studies have suggested that Neanderthals may have had light skin and reddish hair colour due to a particular non-synonymous variation in MC1R ...different DNA variants than found ...
15
Increased mitochondrial DNA diversity in ancient Columbia River basin Chinook salmon Oncorhynchus tshawytscha
... from ancient specimens, allowing for more direct characterizations of past dynamics ...from ancient samples has con- firmed large losses in diversity for many species including musk ox (Ovibos moschatus) ...
26
Re-inventing ancient human DNA
... in ancient DNA experiments is post mortem DNA damage ...[30,31]. DNA damage can be described as a set of lesion-induced substitutions caused by cytosine deamination events, producing C to T ...
12