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Anti-sense

The sense behind retroviral anti sense transcription

The sense behind retroviral anti sense transcription

... retroviral anti- sense transcription stems from studies of Human T- Lymphotropic Viruses (HTLV), particularly ...HTLV-1 sense transcription by recruiting essential transcription factors, such as ...

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Kinetics and mechanisms of steps in anti sense oligonucleotide synthesis

Kinetics and mechanisms of steps in anti sense oligonucleotide synthesis

... growth. Anti-sense oligonucleotides can activate RNase H to cleave the target mRNA strand by acting as the DNA mimic in the required RNA:DNA ...the anti-sense oligonucleotide to function by ...

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Making (anti-) sense out of huntingtin levels in Huntington disease

Making (anti-) sense out of huntingtin levels in Huntington disease

... Recently it has been suggested that in polyQ disorders bidirectional RNA transcription could play a role in the disease pathology by deregulation of the sense transcript [8,18]. It was hypothesized that a ...

11

Expression profile analysis of antisense long non-coding RNA identifies WDFY3-AS2 as a prognostic biomarker in diffuse glioma

Expression profile analysis of antisense long non-coding RNA identifies WDFY3-AS2 as a prognostic biomarker in diffuse glioma

... clinicopathological features of the selected patients are listed in Table 1. Out of the whole transcriptome mRNAs, 420 antisense lncRNAs were identified. SAM with R package “samr” was performed to detect the dif- ...

10

Localization of cystic fibrosis transmembrane conductance regulator mRNA in human fetal lung tissue by in situ hybridization

Localization of cystic fibrosis transmembrane conductance regulator mRNA in human fetal lung tissue by in situ hybridization

... The fetal pulmonary epithelium secretes fluid. Cl transport is presumed to provide the driving force for net fluid secretion, although the cellular mechanisms have not been well identified in the fetus. The cystic ...

8

Tumor suppression by small molecule inhibitors of translation initiation

Tumor suppression by small molecule inhibitors of translation initiation

... eIF4E anti-sense RNA or its activity by ectopic expression of 4E-BPs partially reverses the transformed phenotypes [9, 12, ...eIF4E anti-sense RNA or agents that induce phosphorylation of ...

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Basal transcription of human topoisomerase II : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Biochemistry at Massey University

Basal transcription of human topoisomerase II : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Biochemistry at Massey University

... Studies utilizing anti-sense RNA fragments genetic suppressor elements have shown that down-regulation of topoisomerase Ila expression can generate drug resistance to etoposide in mammal[r] ...

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Undetected antisense tRNAs in mitochondrial genomes?

Undetected antisense tRNAs in mitochondrial genomes?

... mitochondrial sense RNA maturation pro- cesses both 5 ′ and 3 ′ extremities of two antisense tRNAs (tRNA Gln and tRNA Ser UCN), and of 5 and 4 anti- sense tRNAs at their 5′ and 3′ extremities, ...

25

Theranostic cRGD-BioShuttle Constructs Containing Temozolomide- and Cy7 For NIR-Imaging and Therapy

Theranostic cRGD-BioShuttle Constructs Containing Temozolomide- and Cy7 For NIR-Imaging and Therapy

... field of diagnostics, for instance, peptides and anti- sense molecules coupled to contrast agents have been shown to be excellent tools for detecting aberrantly expressed receptors and[r] ...

14

piRNA clusters and open chromatin structure

piRNA clusters and open chromatin structure

... both sense and anti-sense piRNAs relative to the TE sequences are produced from the clus- ...[22,37,38]. Anti-sense precursor transcripts from dual-stranded piRNA clusters are processed ...

12

HSP70: a promising target for laryngeal carcinoma radiaotherapy by inhibiting cleavage and degradation of nucleolin

HSP70: a promising target for laryngeal carcinoma radiaotherapy by inhibiting cleavage and degradation of nucleolin

... Previous studies have shown that heat shock proteins (HSPs) were upregulated in various types of tumors and were associated with histological grade, recurrence and metastasis of malignant tumors. In this study, we ...

7

MicroRNA-1 Participates in Nitric Oxide-Induced Apoptotic Insults to MC3T3-E1 Cells by Targeting Heat-Shock Protein-70

MicroRNA-1 Participates in Nitric Oxide-Induced Apoptotic Insults to MC3T3-E1 Cells by Targeting Heat-Shock Protein-70

... In summary, this study showed that exposure of MC3T3-E1 cells to SNP time-dependently elevated cellular NO and ROS levels. In parallel, SNP de- creased cell survival and induced DNA fragmentation and cell apoptosis. ...

10

Neuropilin 1 mediates epicardial activation and revascularization in the regenerating zebrafish heart

Neuropilin 1 mediates epicardial activation and revascularization in the regenerating zebrafish heart

... nrp1a anti-sense riboprobe (nrp1a AS) (middle left panels) and negative control sense (nrp1a S) riboprobe (lower left panels), signal is observed as a dark blue stain within the section, black arrows ...

59

Multifunctional RNA Processing Protein SRm160 Induces Apoptosis and Regulates Eye and Genital Development in Drosophila

Multifunctional RNA Processing Protein SRm160 Induces Apoptosis and Regulates Eye and Genital Development in Drosophila

... protein. Anti-human SRm160 antibody directed against these initial 153 residues (Blencowe et ...2). Anti-human and anti- Drosophila antibodies reveal a protein of identical mobility at 150 kDa ...

20

Making sense of electrical sense in crayfish

Making sense of electrical sense in crayfish

... The five sensory modalities of humans are also found in a wide range of invertebrates. Other vertebrates have evolved additional special senses, such as the magnetic sense, which are also found in some ...

7

Making Sense of Internalized Anti Gay Prejudice from the Perspective of Men Who Have Sex with Men

Making Sense of Internalized Anti Gay Prejudice from the Perspective of Men Who Have Sex with Men

... a sense of wanting to “fit ...a sense that for some gay men who become defined by difference in a “culture of homophobia” and heterosexism, this was exacerbated and perpetuated by ...

163

A White Savior, Savagery, and Criminality in the City of "Multitudinous Opportunity" in Zootopia

A White Savior, Savagery, and Criminality in the City of "Multitudinous Opportunity" in Zootopia

... While being a film that allows its audience to think on a more human level about the so- called “post-racial” America, the film is also regressive in that it prizes a White savior for people of color. Bineham (2015) ...

16

Word Sense Induction for Novel Sense Detection

Word Sense Induction for Novel Sense Detection

... appropriate sense gran- ...each sense as a weighted list of ...of sense granularity determi- nation via non-parametric formulations, such as a Hierarchical Dirichlet Process (HDP: Teh et ...

11

RNA-protein interactions at the 3' end of the hepatitis A virus RNA.

RNA-protein interactions at the 3' end of the hepatitis A virus RNA.

... Although they were used in a higher molar ratio (the same amounts of radioactivity were used for all cross-linking/label transfer mixtures, irrespective of the RNA size), control runoff transcripts of pGEM-1 were unable ...

8

A24 1403 5 1401 Reference Apr62 pdf

A24 1403 5 1401 Reference Apr62 pdf

... BRANCH ON Unconditional Carriage Channel #9 Carriage Channel # 12 "Last Card" switch sense switch A Sense Switch B* Sense Switch C* Sense Switch D· Sense Switch E* Sense Switch F* Sense [r] ...

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