Anticancer Agent
EVALUATION OF CYTOTOXICITY AND APOPTOTIC POTENTIAL OF OPHIORRHIZA PECTINATA ARN – A POTENT ANTICANCER AGENT
... Rubiaceae. Ophiorrhiza L. is a notably species-rich genus consisting of 321 species, five varieties, and one subspecies [9] and found in wet tropical forests of South-East Asia, extending to Australia, New Guinea, and ...
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Molecular genetic evaluation of Cichorium endivia L. as an anticancer agent against colorectal cancer
... inflammation and hepatoprotective ctivity is mainly due to its high levels of antioxidant The aim of this study is to investigate Cichorium L. as an anticancer agent and an immune response drug (CRC). The ...
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Systemic use of tumor necrosis factor alpha as an anticancer agent
... effective anticancer agent in in vitro and in vivo preclinical ...an anticancer treatment will rely on exploring ways to reduced systemic toxicity and exploit novel mechanisms of action to deliver ...
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Nrf2 activity as a potential biomarker for the pan-epigenetic anticancer agent, RRx-001
... against anticancer drug-induced cytotoxic effects. RRx-001 is a new anticancer agent that generates reactive oxygen and nitrogen species, and leads to epigenetic alterations in cancer ...
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Production of l asparaginase as anticancer agent by alomonasalkaliantarctica isolated from marine samples
... In conclusion, the marine isolate Halomonasalk aliantarctica was identified as a promising candidate for L-asparaginase production and it showed the enzyme activity maximized in nutrition medium supplemented with 1.0% ...
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Efficient Production of Anticancer Agent Cordycepin by Repeated Batch Culture of Cordyceps militaris Mutant
... bioactive anticancer agents found in Cordyceps species (summer grass-winter ...the anticancer agent cordycepin from Cordyceps militaris in a large scale is currently an acute issue that might be ...
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<p>Pleiotropic Anticancer Properties of Scorpion Venom Peptides: <em>Rhopalurus princeps</em> Venom as an Anticancer Agent</p>
... Abstract: To date, the success of conventional chemotherapy, radiotherapy, and targeted biological therapies in cancer treatment is not satisfactory. The main reasons for such outcomes rely on low target selectivity, ...
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From METS to malaria: RRx 001, a multi faceted anticancer agent with activity in cerebral malaria
... epigenetic anticancer agent currently in Phase 2 clinical development for multiple tumour types, with activity mediated through increased nitric oxide (NO) production and PPP ...
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Properties of realgar bioleaching using an extremely acidophilic bacterium and its antitumor mechanism as an anticancer agent
... Realgar is a naturally occurring arsenic sulfide (or Xionghuang, in Chinese). It contains over 90% tetra-arsenic tetra- sulfide (As 4 S 4 ). Currently, realgar has been confirmed the antitumor activities, both in vitro ...
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Gambogic Acid as Anticancer Agent: A Review
... Researchers conducted extensive work on natural products to explore their role as an anticancer agent in last decades. Among these products, GA has attained popularity as a promising novel antitumor ...
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DELTA-TOCOTRIENOL IS THE MOST BIOACTIVE ANTICANCER AGENT AGAINST GASTRIC CANCER
... Preclinical studies have shown that, in contrast to tocopherols, tocotrienols have unique bioactive properties against cancer cells. [13,20] Furthermore our preclinical and clinical studies in pancreatic cancer showed ...
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In vitro assessment of a computer-designed potential anticancer agent in cervical cancer cells
... It is well-recognised that drug discovery and subsequent development is a timely- and expensive process. Com- puter-based technology that combines chemical- and bio- logical parameters in order to optimize drug ...
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Improved delivery of the anticancer agent citral using BSA nanoparticles and polymeric wafers
... The decrease in cell proliferation with increasing citral concentrations indicates that citral is being released from the BSA nanoparticles and entering the cells.. There was no signi[r] ...
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Diacetoxyscirpenol as a new anticancer agent to target hypoxia- inducible factor 1
... have anticancer activity in preclinical and clinical studies ...its anticancer effect, this conflicting point should be considered in developing diacetoxyscirpenol as an adjuvant cancer ...
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Synthesis and Study of Modified Polyvinyl Alcohol Containing Amino acid moieties as Anticancer Agent
... Fifteen compounds modified polyvinyl alcohol were selected for examend their anticancer activity in Bio-technology research center, Al-Nahrain University, Baghdad, Iraq. Two cell lines were used (mice intestines ...
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A novel anticancer agent SNG1153 inhibits growth of lung cancer stem/progenitor cells
... was reversed by MG132, a proteasome inhibitor (Figure 5C). RT-PCR assay confirmed that β-catenin mRNA level was unchanged in the presence of SNG1153 (Figure 5D). Further investigation by nucleocytoplasmic separation ...
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STRUCTURAL UNDERSTANDING OF CYTOTOXIN 1 OF NAJA SPUTATRIX: A POTENTIAL ANTICANCER AGENT
... Snake venom cytotoxin from different Naja species possesses significant cytotoxic activity on tumor cells. The cytoxin from snake venom can exert a plethora of biological activities including depolarization and muscular ...
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LITERATURE AND SCIENTIFICALLY CARVONE IS AN ANTICANCER AGENT
... Together all, this review suggests that CAV has anticancer activity in a number of test systems. Cytotoxic, tumor suppression, immunomodulatory, antiproliferative and inhibition of cancer cell migration, and ...
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Systemic delivery of the anticancer agent arenobufagin using polymeric nanomicelles
... (ABG-PNs) were prepared with mPEG-PLGA using the solvent-diffusion technique. Prepared micelles were charac- terized by particle size, morphology, entrapment efficiency (EE), and drug release in vitro. Cellular uptake ...
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NON-AQUEOUS PARENTERAL PREPARATION OF AN ANTICANCER AGENT – A REVIEW
... of anticancer drugs and they may be separated into four distinct types: alkylating agents, anti-tumour antibiotics, plant alkaloids and ...antimitotic agent and is used in combination with other agents for ...
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