Apolipoprotein A-I gene
Undetectable apolipoprotein A I gene expression suggests an unusual mechanism of dietary lipid mobilisation in the intestine of Cyprinus carpio
... glycerol, 1·mmol·l –1 EDTA pH 8.0, 0.25% (w/v) Bromophenol Blue and 0.25% (w/v) Xylene Cyanol ] and separated by electrophoresis in 1% (w/v) agarose gel containing 6% (v/v) formaldehyde. Samples were run in duplicate; ...
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High density lipoprotein deficiency with xanthomas A defect in reverse cholesterol transport caused by a point mutation in the apolipoprotein A I gene
... triglycerides are normal. The genetic defect could be identified as a base insertion into the third exon of the apoA-I gene. This leads to a nonsense peptide sequence beginning at amino acid 5 of the mature ...
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Apolipoprotein A-I gene transfer exerts immunomodulatory effects and reduces vascular inflammation and fibrosis in ob/ob mice
... response. Apolipoprotein A-I (apo A-I) is the principal apolipoprotein of HDL and plasma levels of this apolipoprotein strongly correlate with HDL choles- terol ...A-I ...
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A frameshift mutation in the human apolipoprotein A I gene causes high density lipoprotein deficiency, partial lecithin: cholesterol acyltransferase deficiency, and corneal opacities
... of apolipoprotein A-I (apo A-I) and of reduced lecithin: cholesterol acyltransferase (LCAT) activity in plasma led to sequence analysis of the genes for apo A-I and LCAT in this patient and ...
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Role of thyroid hormones in apolipoprotein A I gene expression in rat liver
... A-I gene expression, we measured synthesis and abundance of cellular apo A-I mRNA and its nuclear precursors in livers of hypothyroid and hyperthyroid ...
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AMPK -1 , and lower APOB gene expression in the liver than 42-day-old broilers. Age had no effect on FAS gene expression. Our results show that the gender and age could act on the expression of genes related to
... (FAS), apolipoprotein A-I (APOA-I), apolipoprotein B (APOB), adiponectin (ADIPOQ), liver kinase B1 (LKB1), and AMP-activated protein kinase α-1 (AMPKα-1) genes was evaluated by ...greater ...
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Inhibition of HIV Replication by Apolipoprotein A I Binding Protein Targeting the Lipid Rafts
... HIV load. Viral RNA was extracted from cell-free plasma using a QIAamp viral RNA minikit (Qiagen) following the manufacturer’s instructions. HIV RNA was quantified by reverse transcriptase quantitative PCR (qRT-PCR) using ...
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Opposite regulation of human versus mouse apolipoprotein A I by fibrates in human apolipoprotein A I transgenic mice
... liver apolipoprotein (apo) A-I gene ex- pression by fibrates was studied in human apo A-I trans- genic mice containing a human genomic DNA fragment driving apo A-I expression in ...
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Apolipoprotein A-I and A-I mimetic peptides: a role in atherosclerosis
... influence gene expression in the macrophages of the lesions, including the expression of costimulatory molecules which participate in the activation of the T cell ...
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Effect of Apolipoprotein E on the Cerebral Load of Latent Herpes Simplex Virus Type 1 DNA
... housekeeping gene (item ...keeping gene from a concentration range of mouse genomic DNA (results are expressed as nanograms of host ...viral gene and the  -actin housekeeping gene by ...
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A nonsense mutation in the apolipoprotein C IIPadova gene in a patient with apolipoprotein C II deficiency
... C-II gene from a patient with apo C-II deficiency has been sequenced after amplification by the polymerase chain ...patient's gene was identified by sequence ...Rsa I restriction enzyme site not ...
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Apolipoprotein A I Q[ 2]X causing isolated apolipoprotein A I deficiency in a family with analphalipoproteinemia
... the apolipoprotein (apo) A-I gene causing ...apoA-I gene identified a nonsense mutation at codon [-2], which we designate as ...
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Interaction between adipocytes and high-density lipoprotein:new insights into the mechanism of obesity-induced dyslipidemia and atherosclerosis
... Adipose tissue is the body’s largest cholesterol pool. A particular characteristic of adipocytes is that cholesterol is found mostly in its free, non-esterified form because of lack of acyl-coenzyme A: cholesterol ...
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Apolipoprotein E gene polymorphisms and migraine
... E4 gene as compared to the APOE E3 gene ...E3 gene containing cells have lower expression of cytokines TNF-a and IL-6 as compared to cells expressing APOE E2 and APOE E4 genes ...
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ASSOCIATION OF CAROTID INTIMA-MEDIA THICKNESS WITH LEPTIN AND APOLIPOPROTEIN B/APOLIPOPROTEIN A-I RATIO REVEALS IMMINENT PREDICTORS OF SUBCLINICAL ATHEROSCLEROSIS IN PSORIASIS PATIENTS
... ± 0.09 mm and 0.656 ± 0.13 mm vs 0.482 ± 0.08 mm respec- tively). Among patients, 26 (32.5 %) reported an abnormal increase in CIMT i.e. above 0.7 mm. Data in Tab. 3 shows intra group comparison in patients of psoriasis, ...
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Apolipoprotein E mRNA expression in mononuclear cells from normolipidemic and hypercholesterolemic individuals treated with atorvastatin
... candidate gene approach reported a strong association between APOE ε 2/ ε 3/ ε 4 genotypes and LDL cholesterol statin response ...APOC1 gene and near APOE, was associated with change LDL cholesterol ...
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APOB codon 4311 polymorphism is associated with hepatitis C virus infection through altered lipid metabolism
... Based on the findings mentioned above, we can specu- late that a relationship exists between HCV infection and lipid metabolism disorders through SNPs of APOB- 100, whereby the AA genotype (minor allele homozy- gote) of ...
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Modification of the apolipoprotein B gene in HepG2 cells by gene targeting
... of apolipoprotein (apo) B. In this study, we tested whether gene-targeting techniques can be used to inactivate one of the apo B alleles in HepG2 cells by homologous recombination using a transfected ...
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Early Expression of the Apolipoprotein (a) Gene: Relationships Between Infants' and Their Parents' Serum Apolipoprotein (a) Levels
... Apo(a) levels during the first postnatal week were significantly correlated with those in each parent and with the mid-parent level (father’s value plus moth- er’s value divided by 2) as[r] ...
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Moving beyond LDL-C: incorporating lipoprotein particle numbers and geometric parameters to improve clinical outcomes
... Abbreviations: apoA-I, apolipoprotein A-I; apoB, apolipoprotein B; LDL, low- density lipoprotein; LDL-C, LDL cholesterol; LDL-P, LDL particle concentration; HDL, high-d[r] ...
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