Array CGH
Array CGH and breast cancer
... described CGH-based distinctions between sporadic and familial cases of breast ...discovery. Array-CGH technology is a fairly recent and important upgrade to the groundbreaking (conventional, ...
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Large cryptic genomic rearrangements with apparently normal karyotypes detected by array-CGH
... (MCA). Array-Comparative Genomic Hybridization (array-CGH) has increased the diagnostic yield of ...by array-CGH (at least 6, and up to 18 ...
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The use of array-CGH in a cohort of Greek children with developmental delay
... through array-CGH or Sin- gle Nucleotide Polymorphisms array (SNP-array) is rapidly becoming the first tier clinical genetic test for patients with unexplained developmental delay/intellectual ...
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Genome wide array-CGH and qPCR analysis for the identification of genome defects in Williams’ syndrome patients in Saudi Arabia
... 2x400 array-CGH technique using the Agilent ...Micro- array kit (complete coverage of known CNVs) was used according to a modified protocol of Agilent's ...the array were acquired with Agilent ...
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Multicolor banding remains an important adjunct to array CGH and conventional karyotyping
... case. Array CGH detected imbalance in an eighth case, where previously, G-banded chromosome analysis had reported a normal ...of array CGH in molecular cytogenetics we conclude that ...
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Array CGH improves detection of mutations in the GALC gene associated with Krabbe disease
... gene-targeted array comparative genomic hybridization (CGH) to analyze the GALC gene in individuals with Krabbe disease in whom sequence analysis with 30-kb deletion analysis identified only one ...of ...
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Selection of competent blastocysts for transfer by combining time-lapse monitoring and array CGH testing for patients undergoing preimplantation genetic screening: a prospective study with sibling oocytes
... Conventional CGH was then introduced to screen all 24 chromosomes of oocytes and embryos with some success ...[58-62]. Array CGH [63-71], single nucleotide polymorphism (SNP) array [72-76] and ...
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Array-CGH characterization and genotype-phenotype analysis in a patient with a ring chromosome 6
... The array-Comparative Genomic Hybridization (aCGH) study was performed using the Agilent Human Genome CGH Microarray Kit (Agilent Technologies, Santa Clara, California, USA) following the Agilent ...
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Diagnostic yield of array CGH in patients with autism spectrum disorder in Hong Kong
... of array CGH experiments has been assessed through the parameters in the quality metric ...the array. The lower the value, the better the quality of the data. The array CGH data of all ...
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The clinical application of array CGH for the detection of chromosomal defects in 20,126 unselected newborns
... Background: Array comparative genomic hybridization (CGH) is a powerful tool for detecting unbalanced chromosomal ...of array CGH in newborn screening, we examined 20,126 unselected ...with ...
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Opening the archives for state of the art tumour genetic research: sample processing for array CGH using decalcified, formalin fixed, paraffin embedded tissue derived DNA samples
... Background: Molecular genetic studies on rare tumour entities, such as bone tumours, often require the use of decalcified, formalin-fixed, paraffin-embedded tissue (dFFPE) samples. Regardless of which decalcification ...
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MLPA for confirmation of array CGH results and determination of inheritance
... recommended array CGH as a first-line test in place of traditional karyotype analysis [7]; implementation of this recommendation requires that any aCGH diagnostic service should be robust, cost-effective ...
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A model based circular binary segmentation algorithm for the analysis of array CGH data
... the array and the number of probes in the sequen- tial data under consideration, the eXtreme model pro- vides an approximation of maximal-t distribution in the form of GEV ...
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Application of Array Based Comparative Genomic Hybridization to Pediatric Neurologic Diseases
... and array techniques have been developed to increase early detection rates of microdeletion and ...investigated. Array com- parative genomic hybridization (array-CGH) has recently been used to ...
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A prenatal missed diagnosed case of submicroscopic chromosomal abnormalities by karyotyping: the clinical utility of array-based CGH in prenatal diagnostics
... pregnancy. Array-based CGH analysis was applied to the affected infant, identified a combination of 18p deletion and 7q ...future. Array-based CGH and karyotyping techniques are complemented ...
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Report of Jacobsen syndrome with a mild facial dysmorphism, severe hearing impairment and thrombocytopenia
... oligo- array (Agilent Technologies, Santa Clara, CA, USA) was used for array CGH ...analysis. Array-CGH was carried out according to the recommendations of the ...
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Distal Xq duplication and functional Xq disomy
... of array CGH, only cytogenetically visible duplications of at least 5–10 Mb in size were ...inversion. CGH array allowed detection of far more smaller duplications that may encompass only one ...
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Original Article Correlating array comparative genomic hybridization findings with histology and outcome in spitzoid melanocytic neoplasms
... and array CGH findings of 10 spiztoid melanocytic ...by array CGH. Further that array CGH can be used to help classify and predict behav- ior of spitzoid melanocytic ...
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Genomic profiling distinguishes familial multiple and sporadic multiple meningiomas
... genome array CGH analysis revealed a significant distinction between sporadic meningiomas with or with- out chromosome 22 ...the array CGH analysis points to the need to unravel potential ...
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A boy with developmental delay and mosaic supernumerary inv dup(5)(p15.33p15.1) leading to distal 5p tetrasomy – case report and review of the literature
... SNP array CGH analysis identified 71 at least partly informative SNPs in the interval of the 5p tetrasomy allowing to deduce the parental origin of the ...the array as indicated by genome-wide ...
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