Asymmetric stem cell division
Brain tumor specifies intermediate progenitor cell identity by attenuating β catenin/Armadillo activity
... During asymmetric stem cell division, both the daughter stem cell and the presumptive intermediate progenitor cell inherit cytoplasm from their parental stem ...
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klumpfuss distinguishes stem cells from progenitor cells during asymmetric neuroblast division
... Asymmetric stem cell division balances maintenance of the stem cell pool and generation of diverse cell types by simultaneously allowing one daughter progeny to maintain a ...
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Asymmetric cell division during T cell development controls downstream fate
... T cell development that recapitulates almost all aspects of development and lineage commitment from thymo- cytes to mature T cells particularly at the β -selection checkpoint (Schmitt and Zúñiga-Pflücker, ...
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Molecular mechanisms controlling asymmetric and symmetric self-renewal of cancer stem cells
... through asymmetric cell division is based on the assumption that CSCs and non-CSCs are epigeneti- cally stable and can thus propagate in a mutually inde- pendent ...cancer cell lines or in ...
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Asymmetric division of cyst stem cells in Drosophila testis is ensured by anaphase spindle repositioning
... in cell shape during the cell cycle, and the cellular architecture within the context of the stem cell ...the cell-cortex marker, Moesin, in only a subset of cells using heatshock ...
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Developing ovarian cancer stem cell models: laying the pipeline from discovery to clinical intervention
... single- cell asymmetric division (SR and differentiation) assays (Figure 4) are less technically challenging and can run concurrently with in vivo ...Single cell clonogenicity assays have been ...
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Asymmetric B Cell Division in the Germinal Center Reaction
... critical cell-cell ...hematopoietic stem cells and developing T cells(Awong et ...of asymmetric cell division, signals that have been described to drive PC differentiation may ...
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Notch regulates the switch from symmetric to asymmetric neural stem cell division in the Drosophila optic lobe
... Fig. 6. L’sc downregulates Notch and is sufficient to induce neuroblasts. (A,A ⬘ ) The proneural factor L’sc is transiently expressed in the most medial neuroepithelial cells (arrow) that are about to transform into ...
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The Stem Cell Division Theory of Cancer
... of cell divisions in stem cells by acting on the stem cell or on the stem cell ...hematopoietic stem cells (HSCs) ...the division of stem cells and promote ...
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Stem cell researchers find their niche
... and asymmetric cell division provides a mechanism for the crucial regulation of stem cell numbers, and Weimin Zhong (Yale University, New Haven, CT, USA) asked whether stem cells ...
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Ephrin Eph signalling drives the asymmetric division of notochord/neural precursors in Ciona embryos
... Asymmetric cell divisions are intensively studied as a mechanism used to generate cell diversity during development, and also to control the self-renewal versus differentiation choice during ...
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Dap160/intersectin binds and activates aPKC to regulate cell polarity and cell cycle progression
... Asymmetric cell division has been proposed as a mechanism for maintaining stem cell numbers while allowing the generation of differentiated cell types (Morrison and Kimble, ...
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Identifying and Characterizing Arabidopsis thaliana Stem Cell Regulators.
... cortical cell layers and derived from the cortex/endodermis initial ...different cell layers are a result of two successive asymmetric cell divisions (ACDs), the first ACD occurs anticlinal to ...
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Hermann, Andrea (2010): Analysis of asymmetric division of hematopoietic stem cells by continuous single cell observation. Dissertation, LMU München: Fakultät für Biologie
... sister cell ratio we plotted cell ratios against FOB and found that cells with the lowest FOB also had the highest ratios (Figure ...a cell, the higher the error rate coming from imprecise area ...
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Uncovering the link between malfunctions in Drosophila neuroblast asymmetric cell division and tumorigenesis
... of asymmetric cell division. The cell fate determinants of neural stem cell self-renewal and their asymmetric localization are also essential in en- suring that the ...
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Regulation of centrosome movements by Numb and the Collapsin Response Mediator Protein during Drosophila sensory progenitor asymmetric division
... that asymmetric Numb distribution leads to the anterior enrichment of an activity that limits centrosome ...during cell division, our biochemical data and genetic epistasis data suggest that CRMP is ...
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Asymmetric T Cell Division and the Self-renewal of Specific Immunity
... T cell in response to infection of a host with an invasive pathogen, the host must respond by producing at least two required and disparate cell populations - one that is responsible for controlling the ...
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Regulation of asymmetric cell division in the epidermis
... Asymmetric cell divisions (ACDs) generate cellular diver- sity during the development of multi-cellular organisms from a single-celled ...The asymmetric division of a progenitor cell ...
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Skin Stem Cell Hypotheses and Long Term Clone Survival - Explored Using Agent-based Modelling
... the asymmetric division scenario (1), all of the 38 lineages remained at the end of three ...(assuming asymmetric division), in contrast to results reported in recent genetic labelling ...
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Asymmetric parametric division rules
... Another common axiom is Symmetry, which states that claimants with equal claims should receive equal awards. Obviously, parametric rules do not generally satisfy Symmetry. We study asymmetric division rules ...
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