ATM gene
Analysis of Exon 19 and 39 of ATM Gene in Brain Tumors; Considering the P53 Accumulation
... We could detect D1853N and F858L polymorphism in four and two patients respectively. The alteration P872T was found in three patients. Interonic polymorphism, IVS 38-8 T→C, exhibited in one patient (Fig. 2) this is the ...
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Association between ATM gene polymorphisms, lung cancer susceptibility and radiation-induced pneumonitis: a meta-analysis
... that this site may be involved in the exon 61 splicing process and that it may cause inaccurate splicing [24]. The precise roles of rs664677 and rs609429 remain unclear [41]. The former loci may participate in regulating ...
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ATM ) gene rs373759, rs664143 polymorphisms and the occurrence risk of coronary artery disease (CAD). Methods:
... (ATM) gene rs373759, rs664143 polymorphisms and the occurrence risk of coronary artery disease ...of ATM were genotyped by polymerase chain reaction-restriction fragment length polymorphism ...of ...
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Case Report A homozygous nonsense mutation of ATM gene in a Chinese family with five ataxia telangiectasia children: lesson for prenatal diagnosis
... (ATM) gene that located on chromosome 11 q22-23 [3]. More than 700 ATM gene mutations have been reported in AT patients ...php? gene=ATM), most are frameshift or non- sense ...of ...
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Upregulated ATM Gene Expression and Activated DNA Crosslink-Induced Damage Response Checkpoint in Fanconi Anemia: Implications for Carcinogenesis
... downstream gene products closely linked with BRCA1 or ...of ATM (ataxia telangiectasia mutated) and p53 induced by irradiation (IR) or mitomycin C (MMC) were ...of ATM in cultured FANCA-mutant cells, ...
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Antisense inhibition of ATM gene enhances the radiosensitivity of head and neck squamous cell carcinoma in mice
... of ATM at mRNA and protein level in SCCVII ...of ATM was dramatically reduced after cells were transfected with ATM AS-ODNs compared with that Sen-ODNs and Mis-ODNs treated groups, which indi- cated ...
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Comprehensive analysis of the ATM, CHEK2 and ERBB2genes in relation to breast tumour characteristics and survival: a population based case control and follow up study
... The ATM gene covers ...CHEK2 gene spans 54.1 kb on chromo- some 22 and the ERBB2 gene covers ...the ATM, CHEK2 and ERBB2 genes and their 10 kb flanking sequences from dbSNP (build 124) ...
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Atm heterozygous deficiency enhances development of mammary carcinomas in p53heterozygous knockout mice
... heterozygous ATM mutations with early onset of breast cancer was found ...the ATM gene, rather than a protein-truncating mutation, which accounts for the majority of mutations in patients with ...
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Phenotypic consequences of somatic mutations in the ataxia- telangiectasia mutated gene in non-small cell lung cancer
... (ATM) gene are frequently found in human cancers, including non-small cell lung cancer ...of ATM function confers sensitivity to ionising radiation (IR) and topoisomerase inhibitors and may thus ...
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Impact of ATM and SLC22A1 Polymorphisms on Therapeutic Response to Metformin in Iranian Diabetic Patients
... In our study, the effect of metformin in the treatment of diabetes or improvement of relevant glycemic traits was not magnified among the carriers of the C allele at rs11212617 in the ATM gene. Our finding ...
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Original Article Hepatitis B virus X stimulates redox signaling through activation of ataxia telangiectasia mutated kinase
... of ATM in both HBX- negative and positive cells, and this increase was strongly suppressed by ...of ATM might reflect HBX-induced oxidative stress rather than DNA ...by ATM inhibitors. These lines of ...
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Atm deletion with dual recombinase technology preferentially radiosensitizes tumor endothelium
... Histological analysis. Sarcoma histology was performed on frozen tissue sections. Tumor and heart frozen specimens were embedded directly in OCT compound (Sakura Finetek) by snap freezing in a dry ice/isopentane slurry ...
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The Design and modeling of input and output modules for an ATM network switch
... LIST OF FIGURES Figure 1 The interaction between SONET and ATM in a network Figure 2 ATM cell format at UNI Figure 3 ATM cell format at 8 8 NNI Figure 4 Relationship between physical lin[r] ...
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The role of telomeres and telomerase in hematologic malignancies and hematopoietic stem cell transplantation
... telangiectasia-mutated gene; ATR: Ataxia telangiectasia and Rad3; ALT: Alternative lengthening of telomeres; ss DNA: Single-strand DNA; ds DNA: Double-strand DNA; TRF1: Telomeric repeat-binding factors 1; TRF2: ...
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Metabolic reprogramming in gastric cancer
... The role of the myofibroblast cell in gastric cancer is not very well documented; studies in scirrhous gastric cancer patients show that an increase in myofibroblast cells is correlated with a worse prognosis (Fuyuhiro ...
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Developing a Smart Approach for ATM Crime Detection and Avoidance with GSM and Voice Command
... the ATM room he enter his mystery PIN number then framework naturally creates OTP and sends to the card holder enlisted versatile number then card holder ought to enter OTP produced for further ...
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A Review Paper on Facial Recognition
... IV. In order to prevent the frauds of ATM in India, it is recommended to prepare the database of all ATM customers with the banks in India & deployment of high resol[r] ...
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Is the future of the ATM past?
... The idea of the ATM configuration being a sub-optimal solution and emerging from fortuitous circumstances or chance developments is also debatable. Cash dispensers did not materialise from the ether nor from ...
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On the ATM adaptation layer
... Our fir.,t mathematical analy.,i$ approach assumed naively a Poisson arrival process, The resuliinq closed queue- ing network uias solved approzimately and an ezpres- "ion for the en[r] ...
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The Drosophila Nbs Protein Functions in Multiple Pathways for the Maintenance of Genome Stability
... We have shown that the Drosophila Nbs protein is required for transport of Rad50 in the nucleus and for prevention of telomere fusion and chromosome break- age. In addition, our results indicate that Nbs can act ...
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