B cell activation
Influenza Virus-Induced Type I Interferon Leads to Polyclonal B-Cell Activation but Does Not Break Down B-Cell Tolerance
... Polyclonal B-cell activation on its own is thought to be able to induce ...with B cells presenting LCMV antigens processed in a nonspecific ...non-LCMV-specific B cells receive ...
10
Mechanisms of anti-Sm B cell activation in autoimmune Fas-deficient mice
... Apoptotic cell (AC)-pulsed BMDCs induce anti-Sm antibody secreting cell (ASC) formation in ...MZ B cells in response to AC immunization suggested that MZ B cells were activated by apoptotic ...
283
T cell–independent B cell activation induces immunosuppressive sialylated IgG antibodies
... T cell–dependent (TD) protein antigen without a proinflammatory costimulus induces not only Tregs, but also immunosuppressive sialylated ...and B cell immune responses, including the production of ...
10
Divergence of transcriptional landscape occurs early in B cell activation
... in B cell ...BCR activation data showing overexpression of Myc, low- ered H3K27me3, and decreased miR26a highlight the multi-factorial nature and cross-dependency of regulatory systems likely to ...
14
Effects of in vitro corticosteroids on B cell activation, proliferation, and differentiation
... of B cell activation, proliferation, and ...as activation and proliferation of high-dose anti-mu or Staphylococcus aureus-stimulated B cells are profoundly suppressed by the presence of ...
9
The role of the antigen signal in LPS-induced B cell activation
... of B cell activation, first proposed almost 20 years ago (Coutinho and Möller 1974, Coutinho and Möller 1975) argued against an active signalling role for surface immunoglobulin (slg) in B ...
208
Non-Antigen-Specific B-Cell Activation following Murine Gammaherpesvirus Infection Is CD4 Independent In Vitro but CD4 Dependent In Vivo
... non-antigen-specific B-cell activation occurs with both B-cell-tropic (16, 22) and non-B-cell-tropic (13, 14, 21) HV infections, it may also represent a means exploited by ...
5
CFTR regulates B cell activation and lymphoid follicle development
... on B cells is critical for antigen presenta- ...antigen, B cells in tertiary LFs could present antigen to other lympho- cytes, which may be further amplified by increased MHC class II expression ...the ...
13
Hyper IgM syndrome associated with defective CD40 mediated B cell activation
... The 17 patients suspected of having X-linked hyper IgM syndrome could be divided into two groups: cells from 13 patients failed to bind the CD40 construct CD40 ligand negative patients, [r] ...
7
B-cell repertoire dynamics after sequential hepatitis B vaccination and evidence for cross-reactive B-cell activation
... total B-cell reper- toire samples, subsampling to 75,000 sequences per sample was conducted and sequences were clustered into clonal lineages using a previously described algo- rithm ...error-corrected ...
13
B cell activation factor (BAFF) induces inflammation in the human fallopian tube leading to tubal pregnancy
... the B cells from apoptosis, or maintain the supply of oxygen and nutrients in inflammatory microenviron- ments ...to B cell provoca- tion, and raise activation of T cells or dendritic cells ...
7
The role of BCR destabilization in antigen processing
... A physical dissociation of the BCR complex was first suggested by the presence of Ig- α in lipid microdomains in the absence of μ m (Figure 2.2B). These findings contrast with a previous report claiming translocation of ...
123
Transient Immunodeficiency During Asymptomatic Epstein-Barr Virus Infection
... B-cell activation.2 This is followed by proliferation of immunoregulatory T cells necessary to contain the B-cell proliferation.35 In this study, we have confirmed the depressed in vitro[r] ...
6
Toll-like receptors in the pathogenesis of human B cell malignancies
... in B-cell activation, maturation and memory and may be involved in the pathogenesis of B-cell ...of B-cell lymphomas has gained much ...normal B cell ...
10
Interleukin-9 Is Associated with Elevated Anti-Double-Stranded DNA Antibodies in Lupus-Prone Mice
... naïve B cells were stimulated with IL-9 in vitro, IL-9 promoted B-cell proliferation and IgM and IgG produc- tion, which were enhanced by concomi- tant stimulation with ...in B cells ...
7
B Cell Infection and Activation by Rabies Virus-Based Vaccines
... that B cell infection and activation serve alongside DC stimulation to generate the prompt and potent an- tibody responses observed following immunization with live rRABV-based ...independent ...
14
The role of Rac GTPases in B cell development and activation
... The B cell developmental abnormalities noted in the Æac-deficient mice analysed required more mechanistic inquiry to uncover why deficiency in Rac2 and also Racl had profound affects on the generation ...
241
B cell receptor revision diminishes the autoreactive B cell response after antigen activation in mice
... gen-activated B cell and the GC or post-GC B cell is critical to an understanding of many autoimmune ...GC B cells or post-GC B cells. We now extend our insight into B ...
13
CVID associated TACI mutations affect autoreactive B cell selection and activation
... a B cell disorder (2). B cell receptor (BCR) and TLR7 and TLR9 responses are found altered in most CVID patients ...to B cells, such as Treg deficiency, a finding associated with ...
12
CD4 T cell activation by B cells in human Leishmania (Viannia)infection
... both activation and inhibition of APC function have been ...inhibits cell activation and antigen presentation while uninfected neighboring DCs are able to upregulate MHCII and costimulatory molecules ...
13