B-cell epitope prediction
Computational Methods in Linear B cell Epitope Prediction
... scales, prediction accuracy could not be improved to a great ...linear B-cell epitopes need to be ...linear B-cell epitope ...
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B-Pred, a structure based B-cell epitopes prediction server
... a B-cell ...named B-Pred, is accessible on the Internet at ...the prediction of potential linear epitopes, as opposed to discontinuous ...linear epitope to a peptidic reagent is ...
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Immunoinformatics and epitope prediction in the age of genomic medicine
... tackle. B- cell epitope prediction is still basically an unsolved prob- ...the prediction of T-cell reactivity is currently at a point where prediction quality is not yet ...
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Analysis of antibody induction upon immunization with distinct NTS DBL1α domains of PfEMP1 from rosetting Plasmodium falciparum parasites
... that B-cell epitope prediction is inform- ative; however, there might be a tendency for skewing to- wards surface epitopes that are present in unstructured ...the cell surface and ...
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Cloning, expression and T cell epitope prediction of fbpA and fbpB genes of Mycobacterium tuberculosis clinical isolates
... the cell wall surface and needed for the survival of ...from cell walls and required for biogenesis in cord factors ...stimulate B cell and T cell ...T cell epitopes of the fbpA ...
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IN SILICO HOMOLOGY STRUCTURE, B CELL AND T CELL EPITOPES PREDICTION OF SERINE/THREONINE PROTEIN KINASE A AGAINST TUBERCULOSIS
... B-cell epitope were predicted by the online server BCPREDS Server ...and B- cell epitopes were determined by VaxiJen server under default conditions (cutoff score ...Eleven ...
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An Integrated In-Silico Approach to Develop Epitope-Based Peptide Vaccine against SARS-CoV-2
... of epitope- based vaccine designing approach. Both B-cell and T-cell epitopes are predicted using integrated computational ...for prediction of protective antigenicity of the ...T ...
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IN-SILICO T-CELL EPITOPE PREDICTION TOOL OF HEPATITIS C VIRUS (HCV)
... Hepatitis C Virus (HCV) is a ssRNA infectious microbe that affects and kills millions of people worldwide annually However, various part of the virus that can be recognized processed and dealt with by immune system, such ...
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American Journal of Medical and Biological Research
... The B and T cell epitopes prediction is done by immune epitope database ...predicted B cell epitopes by Bepipred linear epitope prediction analysis and T ...
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Specificities of Human CD4+ T Cell Responses to an Inactivated Flavivirus Vaccine and Infection: Correlation with Structure and Epitope Prediction
... T cell response to C should also be seen in the light of its potential helper function in the production of neutral- izing antibodies directed toward ...virus, B cells expressing envelope protein-specific ...
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Immunoinformatics Approach Identified Two Highly Conserved B and T Cell Epitopes, LEASKRWAF and DSPLEASKRWAFRTG, for Effective Vaccine Design against Ebola and Marburg Viruses
... Nowadays, epitope based vaccine design against lethal viruses through bioinformatics has become popular because of its short study time, increased strength to predict effective epitopes and the availability of ...
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Expression of an Antigenic Adenovirus Epitope in a Group B Coxsackievirus
... more protein synthesis be reconciled with a lower yield of infectious virus in CVB3-PL2-Ad2L1-infected cells? We pro- pose the following mechanism. The 2Apro cleaves the 1D/Ad2 polypeptide site in the chimeric virus in ...
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Inclusion of a specific T cell epitope increases the protection conferred against foot and mouth disease virus in pigs by a linear peptide containing an immunodominant B cell site
... same B- and T- cell FMDV epitopes displayed in the dendrimeric pep- ...the B peptide or with TB, a peptide in which the B-epi- tope was in tandem with the T-cell epitope (Table ...
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Advancement and applications of peptide phage display technology in biomedical science
... cell specific peptides [142–145] are used for synthesizing PDCs for cancer therapy. After more than decades of re- search, lots of PDCs have been discovered, and some have been clinically evaluated, although none ...
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Circulation autoantibody against Lamin A/C in patients with Sjögren’s syndrome
... Based on the above analysis of the experimental results and clinical information, we inferred that antibodies of a certain antigen could recognize similar epitope on another potential antigen by cross-reaction. ...
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Title: FORMULATION & EVALUATION OF TRANSDERMAL PATCH OF TOLBUTAMIDE Author: Ganju Eisha* and Ganju Kuldeep Keyword: Transdermal drug delivery, Matrix patch preparation, Membrane controlled Patch, tolbutamide, HPMC, PVP, In- vitro skin permeation studies.Page No: 01-04Abstract: The aim of the present investigation was to prepare tolbutamide transdermal patches by solvent casting technique using the HPMC and PVP polymer in different ratios. The systems were evaluated for var ious in- vitro parameters like (Thickness, Folding endurance, Moisture content, Moisture uptake, etc). In- vitro permeation studies were performed by using Franz diffusion cell. Variations in drug permeation profile were observed among various formulations. From all the formulations, formulation P4 was selected as the best formulation and formulation was stable for period of 90 days stability study. Keywords: Transdermal drug delivery, Matrix patch preparation, Membrane controlled Patch, tolbutamide, HPMC, PVP, In- vitro skin permeation studies. Download PDF
... D cell kick the bucket. Unfused B cells bite the dust as they have a short life ...theB cell- myeloma half and halves get by, since the HGPRT quality originating from the B cells is ...of ...
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Identification of a conserved linear B cell epitope in the M protein of porcine epidemic diarrhea virus
... the epitope of the M protein, a panel of 17 par- tially overlapping peptides (M1–M17) spanning the tM protein, as shown in Figure 1, were expressed succes- ...
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Identification of B Cell Epitope of Dengue Virus Type 1 and Its Application in Diagnosis of Patients
... of B-cell epitopes for DEN can provide important information for the development of a safe and effective dengue vaccine and contribute to the understanding of the pathogenesis of DEN and immunological ...
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Epitope specificity determines pathogenicity and detectability in ANCA associated vasculitis
... linear epitope on MPO (aa 447–459), an epitope masked by a CP frag- ment, which is a crucial finding concerning this group of ...this epitope, further ...
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Identification of a novel linear B cell epitope in the UL26 and UL26 5 proteins of Duck Enteritis Virus
... the epitope of DEV UL26 that was recognized by mAb 1C8, a set of GST fused proteins (Figure 2) were expressed in prokaryotes and used together to identify the epitope by both western blotting and ...the ...
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