B cells
B cells in autoimmunity
... of B cell-depleting therapy in ameliorating rheumatoid inflammation and joint destruction has docu- mented a role for B cells in RA but also in other autoimmune diseases, such as idiopathic ...
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Prognostic value of B cells in cutaneous melanoma
... of B cells was associated with impaired T cell tumor in- filtration and cytotoxicity in the murine B16 melanoma model [15, ...T cells, including B cells ...infiltrating B ...
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B cells: no longer bystanders in liver fibrosis
... by cells that mediate the innate and adaptive immune responses play a critical role in regulating the synthesis of ECM components by ...Th2 cells to hepatic fibrosis has been well ...hepatic B ...
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Impact of B cells to the pathophysiology of multiple sclerosis
... that B cells usually act as a source of both pro- and anti-inflammatory cyto- kines [48, ...activated B cells are considered potent producers of protective and patho- genic ...cytokines. ...
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Targeting B cells for the treatment of rheumatoid arthritis
... mediate B cell activation is qualitatively different from that observed with CD19 and ...of B cells directly through enhancement of BCR sig- ...more cells surviving to enter the cell cycle, ...
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Activation of human B cells by phosphorothioate oligodeoxynucleotides
... blood cells including neutrophils, adherent mononuclear cells, E rosetting cells, and non-E rosetting cells ...K562 cells express five cell surface proteins, ranging in size from 20 to ...
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Differential expression of chemokine receptors on peripheral blood B cells from patients with rheumatoid arthritis and systemic lupus erythematosus
... of B cell migration, we analyzed chemokine receptor expression on peripheral blood B ...little B cell accumulation at the site of chronic inflammation ...peripheral B cells; however, ...
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GIFT4 fusokine converts leukemic B cells into immune helper cells
... T cells could have the capability to directly kill primary CLL cells, we co-cultured primary CLL cells with autologous GIFT4-CLL cell-primed T ...T cells primed by GM-CSF and IL-4 or PBS ...
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Regulatory T cells induced by B cells: a novel subpopulation of regulatory T cells
... T cells play a crucial role in the homeostasis of the immune ...T cells, several subsets of Foxp3 - regulatory T cells, such as T helper 3 (Th3) cells and type 1 regulatory T (Tr1) ...
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Regulatory B Cells Are Inversely Associated with Disease Activity in Rheumatoid Arthritis
... of B cells se- creting ...IL-10+ B cell was elevated in RA or other rheumatic dis- eases, however, the study did not investigate the association with clinical ...IL-10+ B cells was not ...
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Original Article IL-10-producing B cells involved in the pathogenesis of Coxsackie virus B3-induced acute viral myocarditis
... (IL-10)-producing B cells, a subset of regulatory B cells, play critical roles in autoimmune and infectious ...IL-10-producing B cells in acute viral myocarditis (AVMC) remains ...
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PD1hi cells associate with clusters of proliferating B-cells in marginal zone lymphoma
... enabling B-cell help [24]. We hypothesised that the PD1 hi cells might associate with proliferating lymphoma ...+ cells were pre- dominantly B-cells and formed clusters but without the ...
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Epstein-Barr virus enters B cells and epithelial cells by different routes.
... In contrast, fusion of virus labeled with AF could be measured with Raji cells and epithelial cells, but not with normal B cells unless cells were previously treated with ammonium chlori[r] ...
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Expression of CXCL12 receptors in B cells from Mexican Mestizos patients with systemic lupus erythematosus
... SLE B cells is unclear but might involve both impaired receptor synthesis and intracellular traf- ...the B-cell ...sorted B cells from ...all B-cell subsets from SLE patients ...
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Skewed CD39/CD73/adenosine pathway in B cells is associated with innate immune hyperactivation in chronic HIV-1 infection
... total B cells (and their subsets) decreased continuously in typical progressors (TPs), but were gradually recovered in complete ...+ B cells inversely correlated with HIV-1 viral load and ...
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B cells as a therapeutic target in autoimmune disease
... antigen-specific B cells is far superior to the nonspecific uptake by other professional antigen-presenting ...of B cells determines which antigen is efficiently presented, particu- larly at ...
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Functional studies on human γδ T cells and their interactions with dendritic cells and B cells
... T cells expressing the Vγ9Vδ2 TCR comprise the most abundant γδ T cell subset in human blood, where they typically account for 1-5% of T cells in healthy adults (Kabelitz and He, 2012, Vantourout and ...
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Dendritic cell regulation of B cells
... Autoimmunity is characterized by the breakdown in tolerance mechanisms that control the autoreactive lymphocytes. Systemic lupus erythematosus (SLE) is a chronic form of autoimmune disease that results from the ...
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Roles of B cells in rheumatoid arthritis
... plasma cells, the B cells in RA can play a critical role in the afferent arm of the immune response (Table ...Thus, B cells can act as highly efficient antigen-presenting cells ...
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Noncognate function of B cells in transplantation
... of B cells, can reject skin allografts as rapidly as wild-type counter parts ...Thus, B cells are necessary for development of lym- phoid organs essential for graft rejection but once those ...
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