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Bacterial model systems and experimental evolution

Experimental Analysis of Molecular Events During Mutational Periodic Selections in Bacterial Evolution

Experimental Analysis of Molecular Events During Mutational Periodic Selections in Bacterial Evolution

... A fundamental feature of bacterial evolution is a succession of adaptive mutational sweeps when fitter mutants take over a population. To understand the processes involved in mutational successions, ...

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Heat degradation of eukaryotic and bacterial DNA: an experimental model for paleomicrobiology

Heat degradation of eukaryotic and bacterial DNA: an experimental model for paleomicrobiology

... In this study, the murine macrophage cell line J774, alone or infected with Mycobacterium smegmatis bacteria, were killed after exposure to 90°C dry heat for intervals ranging from 1 to [r] ...

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Bacterial melanin crosses the blood–brain barrier in rat experimental model

Bacterial melanin crosses the blood–brain barrier in rat experimental model

... Arterial blood was sampled to obtain the level of I-BM at different time points after injection. After systemic perfusion with saline, animals were decapitated and brain, spinal cord, liver and kidney samples were ...

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Systems evolution: the conceptual framework and a formal model

Systems evolution: the conceptual framework and a formal model

... What is of special interest in this study is the dynamical behaviour of open systems, especially the process when an open system changes from one level of complexity to another o[r] ...

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An Experimental Study on Bacterial Concrete

An Experimental Study on Bacterial Concrete

... as Bacterial Concrete where bacteria is induced in the mortars and concrete to heal up the ...a model laboratory bacterium, which can produce calcite precipitates on suitable media supplemented with a ...

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Experimental Study on Bacterial Concrete

Experimental Study on Bacterial Concrete

... We have selected Bacillus Subtilis, since it produces Calcium Carbonate and due to ease of availability. It is also known as Hay Bacillus or Grass Bacillus, is a gram-positive, Catalane-positive bacterium, found in soil ...

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Analysis of genetic systems using experimental evolution and whole-genome sequencing

Analysis of genetic systems using experimental evolution and whole-genome sequencing

... the evolution of their populations, and they attempted to discover competing clonal lineages by sequencing the hand- ful of candidate genes suggested by their whole-genome sequencing in search of alternative ...

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Analysis of genetic systems using experimental evolution and whole genome sequencing

Analysis of genetic systems using experimental evolution and whole genome sequencing

... the evolution of their populations, and they attempted to discover competing clonal lineages by sequencing the hand- ful of candidate genes suggested by their whole-genome sequencing in search of alternative ...

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Model-based evolution of collaborative agent-based systems

Model-based evolution of collaborative agent-based systems

... these systems has emerged as a way to ensure that relevant requirements are rendered properly as the abstract models from the prob- lem domain evolve into increasingly more detailed and complete ones used to ...

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Bacterial evolution: Resistance is a numbers game

Bacterial evolution: Resistance is a numbers game

... dispensable. Experimental studies of the evolution of plasmids and bacteria are beginning to tease apart the mechanisms by which plasmids might persist through, for example, compensatory evolution or ...

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Adaptation and Specialization in the Evolution of Bacterial Metabolism

Adaptation and Specialization in the Evolution of Bacterial Metabolism

... the evolution of metabolism despite selection for rate. Introduction Systems biology is beginning to provide insight into how interactions within complex networks give rise to the holistic behavior of ...

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The evolution of domain-content in bacterial genomes

The evolution of domain-content in bacterial genomes

... null model to future work, it is clear that the basic ingredients for such a multiplicative noise process are already ...the model only constrains the rela- tive rates of domains in different functional ...

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Selection and Robustness in Bacterial Genome Evolution

Selection and Robustness in Bacterial Genome Evolution

... neutral evolution, I carried out simulations in which the number of nucleotide substitutions placed match the value of observed nucleotide differences in each multiple sequence alignment (the Obs column in Tables ...

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Drosophila Embryos as Model Systems for Monitoring Bacterial Infection in Real Time

Drosophila Embryos as Model Systems for Monitoring Bacterial Infection in Real Time

... as model systems for following bacterial infection in real ...of bacterial cells of the insect pathogen Photorhabdus leads to a rapid ‘freezing’ phenotype of the hemocytes associated with ...

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Drosophila embryos as model systems for monitoring bacterial infection in real time

Drosophila embryos as model systems for monitoring bacterial infection in real time

... as model systems for following bacterial infection in real ...of bacterial cells of the insect pathogen Photorhabdus leads to a rapid ‘freezing’ phenotype of the hemocytes associated with ...

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Data Collection to Support a Simplified Bacterial Regrowth Model for Distribution Systems

Data Collection to Support a Simplified Bacterial Regrowth Model for Distribution Systems

... The water quality parameters measured at each sampling station were disinfectant residual (free chlorine in Durham and combined chlorine in Raleigh), disinfectan demand, disinfectant de[r] ...

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Experimental Evolution with Caenorhabditis Nematodes

Experimental Evolution with Caenorhabditis Nematodes

... Evolution in variable environments The difference in trait values displayed by a single genotype across multiple environments is known as phenotypic plastic- ity, long thought to be a key element in structuring ...

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Phenotypic plasticity and experimental evolution

Phenotypic plasticity and experimental evolution

... ANCOVA model without wheel running ...the model with wheel running (–83.7). As the latter model contains one additional parameter (estimating the effect of wheel running), twice the difference in ln ...

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Cancer in Light of Experimental Evolution

Cancer in Light of Experimental Evolution

... in experimental evolution for epistasis among beneficial mutations ...in bacterial populations, in which certain mutations which compensate for the cost of antibi- otic resistance are deleterious in ...

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Evolution of Specialists in an Experimental Microcosm

Evolution of Specialists in an Experimental Microcosm

... ABSTRACT The impact of adaptation on the persistence of a balanced polymorphism was explored using the lactose operon of Escherichia coli as a model system. Competition in chemostats for two substitutable ...

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