Basal-Like Phenotype Carcinoma
Differential Expression of Glu Tubulin in Basal Like Phenotype Carcinoma of the Mammary Gland
... identify basal-like tumors with widely available standard pathologic tools ...a basal-like phenotype carcinoma (BPC), and tumors that were negative for all these four markers as ...
6
The expression of the ubiquitin ligase SIAH2 (seven in absentia homolog 2) is mediated through gene copy number in breast cancer and is associated with a basal like phenotype and p53 expression
... The flow of patients through the study according to the Reporting Recommendations for Tumor Marker Prog- nostic Studies (REMARK) criteria is listed in Supple- mentary Table 1 in Additional file 1 [7] The first cohort was ...
10
/ISSN:1936-2625/IJCEP0001032 Case Report Primary squamous cell carcinoma of the breast with unusual basal-HER2 phenotype
... like phenotype: “triple-negative” (ER, PR and HER2-negative) and overexpresses basal cyto- keratins, such as CK5/6, CK14 and EGFR ...also basal-like ...
7
Original Article p16 expression in basal-like breast carcinoma
... The basal- like breast carcinoma (BLBC) class is a molecu- lar subtype of breast cancer that usually shows a triple-negative phenotype [3] and constitute about 15% of invasive cancers ...of ...
8
Expression of thyroid transcription factor-1 is associated with a basal-like phenotype in breast carcinomas
... TTF-1 (clone SPT24) expression was seen in 7 of 247 cases (2,8%) in this material (Table 2). Positive staining was shown in 6 surgical specimens and in one pre- operative core needle biopsy (Figure 1). Three cases had a ...
6
Basal-like grade III invasive ductal carcinoma of the breast: patterns of metastasis and long-term survival
... showing basal marker ...myoepithelial phenotype, as defined by CK14, smooth muscle actin, or S100 protein ...these basal markers have a more aggressive clinical behaviour when compared to those with ...
12
Establishment and characterization of three stable Basal/HER2-positive breast cancer cell lines derived from Chinese breast carcinoma with identical missense mutations in the DNA-binding domain of TP53
... [31], basal (EGFR, SPARC, Vimentin, and caveolin1–2), pluripotent (CD44 [32], and Stat3α/β, OCT-4, SOX2, and Nanog [33, 34]) and prog- nosis (CD146 and VDR) markers by western ...the basal/ HER2+ ...
15
WNT5B governs the phenotype of basal-like breast cancer by activating WNT signaling
... breast carcinoma cases/patients from cBioPortal and found that Myc and CCND1 were highly amplified at the DNA level in breast ...between basal-like and luminal breast cancers, es- pecially the ...
19
Metaplastic carcinoma of the breast: an immunohistochemical study
... luminal, basal-like, normal breast- like and HER2 positive ...with basal-like immunophenotype as defined by c-DNA micro- arrays and may help in categorizing MBC under one of these ...
10
Morphological and immunophenotypic analysis of basal-like carcinoma of the breast
... between basal and luminal/ductal epithelial ...becoming basal or luminal/ductal cell types, but with some that do not become so terminally ...that basal-like tumours will display some ...
9
Comedo-DCIS is a precursor lesion for basal-like breast carcinoma: identification of a novel p63/Her2/neu expressing subgroup
... of basal carcinomas [4], however, clinical trials with EGFR tyrosine kinase inhibitors and Cetuximab have been largely disappointing ...[5]. Basal or basal-like breast carcinomas express p63, ...
11
Epidemiology of basal-like breast cancer.pdf
... Interventions to reduce the risk of basal-like breast cancer have strong prior justification. In a summary of existing data on breast cancer among younger African- American women, Bernstein et al. [43] ...
17
Expression of P 16 ink4a in basal like triple negative breast carcinoma in Sudanese women
... 18. Rakha EA, Elsheikh SE, Aleskandarany MA, Habashi HO, Green AR, Powe DG, El-Sayed ME, Benhasouna A, Brunet JS, Akslen LA, Evans AJ, Blamey R, Reis-Filho JS, Foulkes WD and Ellis IO (2009) Triple-negative breast ...
12
Morphometric characteristics of basal cell carcinoma peritumoral stroma varies among basal cell carcinoma subtypes
... As a model for the interaction between epithelial tumor cells and stroma, basal cell carcinomas (BCC) offer a number of unique opportunities to study these processes. In addition to being the most common malignant ...
7
Basal cell carcinoma-a case report and review
... A 64 years old female patient presented to our department, with an ulcerated exophytic growth on the lateral aspect of the ala of the nose on the left side of the patient’s face, measuring approximately 1x1cm in size. On ...
5
Tumor interactions with soluble factors and the nervous system
... from carcinoma to ...invasive carcinoma without distant metastasis, but mutations in 35 percent of the samples of primary invasive carcinoma with distant metastasis ...
6
Basal cell carcinoma: 10 year experience with electrochemotherapy
... As the prevalence of BCC rises with aging of the popu- lation, clinicians involved in BCC treatment face an increasing number of challenging scenarios. These are the patients with laBCC, hereditary basal cell ...
12
Incidence and outcome of cutaneous malignancies in Coimbatore Medical College Hospital, Coimbatore
... These are multiple, irregular, small scaly / warty lesions seen over the sun exposed areas due to hyperkeratosis. Clinically, they are usually dry, rough, and adherent and appear dirty brown in colour. The lesions occur ...
154
Epithelial to mesenchymal transition induces stem cell like phenotype in renal cell carcinoma cells
... A498 cells were treated with CsA (10 μM)/TGF-β (5 ng/ ml) in separate set of experiments and morphological changes were observed at 48 h. Light microscopy images showed disruption of cell to cell junctions and distinct ...
13
Keratotic and Pigmented Basal Cell Carcinoma
... BCC compromises 60% - 80% of basal cell carcinomas and is most common over the skin of the forehead. Such tumours of the face have the propensity to invade the skull, nares, orbit or temporal bone thus leading to ...
5